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SIRT1 Produits

(Sirtuin 1 (SIRT1))
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined\; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008].

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Catégories SIRT1 en vedette

SIRT1 Anticorps

High quality antibodies with extensive validation data.

SIRT1 Kits ELISA

Reliable ELISA kits for a wide range of species.

SIRT1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SIRT1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (5)
  • (7)
N° du produit ABIN729853
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (3)
  • (5)
N° du produit ABIN565071
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, IF
Validations
  • (9)
N° du produit ABIN6147784
Quantité 100 μL
Fiche technique Fiche technique

SIRT1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (8)
  • (1)
N° du produit ABIN6959485
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (4)
  • (1)
N° du produit ABIN6959487
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6970229
Quantité 96 tests
Fiche technique Fiche technique

SIRT1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7125104
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1320039
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7398221
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits SIRT1

Balaha, Alamer, Eisa, Aljohani: "Shikonin Alleviates Gentamicin-Induced Renal Injury in Rats by Targeting Renal Endocytosis, SIRT1/Nrf2/HO-1, TLR-4/NF-κB/MAPK, and PI3K/Akt Cascades." dans: Antibiotics (Basel, Switzerland), Vol. 12, Issue 5, (2023) (PubMed).

Zbroch, Bazyluk, Malyszko, Koc-Zorawska, Rydzewska-Rosolowska, Kakareko, Hryszko: "The Serum Concentration of Anti-Aging Proteins, Sirtuin1 and αKlotho in Patients with End-Stage Kidney Disease on Maintenance Hemodialysis." dans: Clinical interventions in aging, Vol. 15, pp. 387-393, (2020) (PubMed).

Yang, Wang, He, Liu, Chen, Wang, Wang, Wang: "Trimetazidine Inhibits Renal Tubular Epithelial Cells to Mesenchymal Transition in Diabetic Rats via Upregulation of Sirt1." dans: Frontiers in pharmacology, Vol. 11, pp. 1136, (2020) (PubMed).

Ascenzi, Barberi, Dobrowolny, Villa Nova Bacurau, Nicoletti, Rizzuto, Rosenthal, Scicchitano, Musarò: "Effects of IGF-1 isoforms on muscle growth and sarcopenia." dans: Aging cell, Vol. 18, Issue 3, pp. e12954, (2019) (PubMed).

Takata, Sakasai-Sakai, Takino, Takeuchi: "Evidence for Toxic Advanced Glycation End-Products Generated in the Normal Rat Liver." dans: Nutrients, Vol. 11, Issue 7, (2019) (PubMed).

Yanes, Zhang, Shen, Weyand, Goronzy: "Metabolic reprogramming in memory CD4 T cell responses of old adults." dans: Clinical immunology (Orlando, Fla.), Vol. 207, pp. 58-67, (2019) (PubMed).

Zhang, Abdukerim, Abilailieti, Tang, Ling, Pan: "The protective effects of orexin a against high glucose-induced activation of NLRP3 inflammasome in human vascular endothelial cells." dans: Archives of biochemistry and biophysics, Vol. 672, pp. 108052, (2019) (PubMed).

Ar Rochmah, Harini, Septyaningtrias, Sari, Susilowati: "Centella asiatica Prevents Increase of Hippocampal Tumor Necrosis Factor-α Independently of Its Effect on Brain-Derived Neurotrophic Factor in Rat Model of Chronic Stress." dans: BioMed research international, Vol. 2019, pp. 2649281, (2019) (PubMed).

Hou, Su, Chen, Niu, Zhao, Wang, Shen: "Association of SIRT1 gene polymorphism and its expression for the risk of alcoholic fatty liver disease in the Han population." dans: Hepatology international, Vol. 12, Issue 1, pp. 56-66, (2018) (PubMed).

Piao, Zhao, Zhu, Inoue, Shibata, Lei, Hu, Yu, Yang, Wu, Xu, Okumura, Ouchi, Murohara, Kuzuya, Cheng: "Chronic Psychological Stress Accelerates Vascular Senescence and Impairs Ischemia-Induced Neovascularization: The Role of Dipeptidyl Peptidase-4/Glucagon-Like Peptide-1-Adiponectin Axis." dans: Journal of the American Heart Association, Vol. 6, Issue 10, (2018) (PubMed).

Synonymes et noms alternatifs relatifs à SIRT1

sirtuin 1 (SIRT1), sirtuin 1 (SRT1), sirtuin 1 (Sirt1), sirtuin 1 L homeolog (sirt1.L), AA673258, Sir2, SIR2, Sir2a, Sir2alpha, SIR2L1, sir2l1, sirtuin, sirtuin 1

Protein level used designations for SIRT1

  • sirtuin 1
  • NAD-dependent deacetylase sirtuin-1
  • NAD-dependent protein deacetylase sirtuin-1
  • SIR2-like protein 1
  • mSIR2a
  • regulatory protein SIR2 homolog 1
  • sir2-like 1
  • sirtuin 1 ((silent mating type information regulation 2, homolog) 1
  • SIR2alpha
  • hSIR2
  • hSIRT1
  • sirtuin type 1
  • sirtuin (silent mating type information regulation 2 homolog) 1
  • NAD-dependent deacetylase sirtuin 1
  • sirtuin1
  • Sir2alpha
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