SIRT2 Produits
(Sirtuin 2 (SIRT2))
Catégories
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined\; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene. [provided by RefSeq, Jul 2010].
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Catégories SIRT2 en vedette
SIRT2 Anticorps
High quality antibodies with extensive validation data.
SIRT2 Kits ELISA
Reliable ELISA kits for a wide range of species.
SIRT2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
SIRT2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (6)
N° du produit
ABIN3020852
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF, RNAi
Validations
- (5)
N° du produit
ABIN564966
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (6)
N° du produit
ABIN3043924
Quantité
100 μg
Fiche technique
Fiche technique
SIRT2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6959488
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6959490
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6959489
Quantité
96 tests
Fiche technique
Fiche technique
SIRT2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7125105
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1320043
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1320041
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits SIRT2
: "Identification of serum protein biomarkers for utrophin based DMD therapy." dans: Scientific reports, Vol. 7, pp. 43697, (2018) (PubMed).: "The effects of melatonin and curcumin on the expression of SIRT2, Bcl-2 and Bax in the hippocampus of adult rats." dans: Brain research bulletin, Vol. 137, pp. 306-310, (2018) (PubMed).
: "The subcellular localization and activity of cortactin is regulated by acetylation and interaction with Keap1." dans: Science signaling, Vol. 8, Issue 404, pp. ra120, (2016) (PubMed).
: "Acetylation of Beclin 1 inhibits autophagosome maturation and promotes tumour growth." dans: Nature communications, Vol. 6, pp. 7215, (2015) (PubMed).
: "A chromatin modifier genetic screen identifies SIRT2 as a modulator of response to targeted therapies through the regulation of MEK kinase activity." dans: Oncogene, Vol. 34, Issue 4, pp. 531-6, (2015) (PubMed).
: "NOTCH-induced aldehyde dehydrogenase 1A1 deacetylation promotes breast cancer stem cells." dans: The Journal of clinical investigation, (2014) (PubMed).
: "Effects of niacin restriction on sirtuin and PARP responses to photodamage in human skin." dans: PLoS ONE, Vol. 7, Issue 7, pp. e42276, (2012) (PubMed).
: "Alcohol-induced alterations in hepatic microtubule dynamics can be explained by impaired histone deacetylase 6 function." dans: Hepatology (Baltimore, Md.), Vol. 48, Issue 5, pp. 1671-9, (2008) (PubMed).
: "Osthole regulates enzyme protein expression of CYP7A1 and DGAT2 via activation of PPARalpha/gamma in fat milk-induced fatty liver rats." dans: Journal of Asian natural products research, Vol. 10, Issue 7-8, pp. 807-12, (2008) (PubMed).
: "The regulation of SIRT2 function by cyclin-dependent kinases affects cell motility." dans: The Journal of cell biology, Vol. 180, Issue 5, pp. 915-29, (2008) (PubMed).
Synonymes et noms alternatifs relatifs à SIRT2
Sirtuin 2 (Sirt2), sirtuin 2 (SIRT2), sirtuin 2 S homeolog (sirt2.S), NAD-dependent deacetylase sirtuin 2 homolog (Sirt2), sirtuin 2 (SRT2), sirtuin 2 (sirt2), sirtuin 2 (Sirt2), sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae) (sirt2), 5730427M03Rik, AtSRT2, BmSirt2, CG5085, D.mel2, Dmel\\CG5085, dSIRT2, sir2, SIR2, SIR2L, Sir2l, SIR2L2, SIRT2, Sirt2, SIRTUIN 2, sirtuin 2, T2K12.8, wu:fb57d05, zgc:55966, zgc:77003Protein level used designations for SIRT2
- CG5085-PA
- Sirt2-PA
- sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae)
- sirtuin 2
- NAD-dependent deacetylase SIRT2
- NAD-dependent deacetylase sirtuin-2
- histone NADC
- silent information regulator 2
- nicotinamide adenine dinucleotide-dependent histone deacetylase
- NAD-dependent deacetylase sirtuin 2 homolog
- NAD-dependent protein deacetylase sirtuin-2
- SIR2-like protein 2
- regulatory protein SIR2 homolog 2
- sir2-related protein type 2
- sirtuin type 2
- sirtuin-like protein 2
- mSIR2L2
- silent mating type information regulation 2, (S.cerevisiae, homolog)-like; sirtuin 2
- 5E5 antigen
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