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SIRT2 Produits

(Sirtuin 2 (SIRT2))

Catégories

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined\; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene. [provided by RefSeq, Jul 2010].

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Catégories SIRT2 en vedette

SIRT2 Anticorps

High quality antibodies with extensive validation data.

SIRT2 Kits ELISA

Reliable ELISA kits for a wide range of species.

SIRT2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SIRT2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (6)
N° du produit ABIN3020852
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IF, RNAi
Validations
  • (5)
N° du produit ABIN564966
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (6)
N° du produit ABIN3043924
Quantité 100 μg
Fiche technique Fiche technique

SIRT2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6959488
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6959490
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6959489
Quantité 96 tests
Fiche technique Fiche technique

SIRT2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7125105
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1320043
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1320041
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits SIRT2

Guiraud, Edwards, Squire, Babbs, Shah, Berg, Chen, Davies: "Identification of serum protein biomarkers for utrophin based DMD therapy." dans: Scientific reports, Vol. 7, pp. 43697, (2018) (PubMed).

Keskin-Aktan, Akbulut, Yazici-Mutlu, Sonugur, Ocal, Akbulut: "The effects of melatonin and curcumin on the expression of SIRT2, Bcl-2 and Bax in the hippocampus of adult rats." dans: Brain research bulletin, Vol. 137, pp. 306-310, (2018) (PubMed).

Ito, Shimazu, Maeda, Shah, Tsunoda, Iemura, Natsume, Suzuki, Motohashi, Yamamoto, Yoshida: "The subcellular localization and activity of cortactin is regulated by acetylation and interaction with Keap1." dans: Science signaling, Vol. 8, Issue 404, pp. ra120, (2016) (PubMed).

Sun, Li, Zhang, Chen, Zhang, Li, Deng, Qian, Jiao, Ji, Li, Wu, Yu, Feng, Zhu: "Acetylation of Beclin 1 inhibits autophagosome maturation and promotes tumour growth." dans: Nature communications, Vol. 6, pp. 7215, (2015) (PubMed).

Bajpe, Prahallad, Horlings, Nagtegaal, Beijersbergen, Bernards: "A chromatin modifier genetic screen identifies SIRT2 as a modulator of response to targeted therapies through the regulation of MEK kinase activity." dans: Oncogene, Vol. 34, Issue 4, pp. 531-6, (2015) (PubMed).

Zhao, Mo, Li, Zou, Cheng, Sun, Xiong, Guan, Lei: "NOTCH-induced aldehyde dehydrogenase 1A1 deacetylation promotes breast cancer stem cells." dans: The Journal of clinical investigation, (2014) (PubMed).

Benavente, Schnell, Jacobson: "Effects of niacin restriction on sirtuin and PARP responses to photodamage in human skin." dans: PLoS ONE, Vol. 7, Issue 7, pp. e42276, (2012) (PubMed).

Shepard, Joseph, Kannarkat, Rutledge, Tuma, Tuma: "Alcohol-induced alterations in hepatic microtubule dynamics can be explained by impaired histone deacetylase 6 function." dans: Hepatology (Baltimore, Md.), Vol. 48, Issue 5, pp. 1671-9, (2008) (PubMed).

Zhang, Xie, Xue, Gu: "Osthole regulates enzyme protein expression of CYP7A1 and DGAT2 via activation of PPARalpha/gamma in fat milk-induced fatty liver rats." dans: Journal of Asian natural products research, Vol. 10, Issue 7-8, pp. 807-12, (2008) (PubMed).

Pandithage, Lilischkis, Harting, Wolf, Jedamzik, Lüscher-Firzlaff, Vervoorts, Lasonder, Kremmer, Knöll, Lüscher: "The regulation of SIRT2 function by cyclin-dependent kinases affects cell motility." dans: The Journal of cell biology, Vol. 180, Issue 5, pp. 915-29, (2008) (PubMed).

Synonymes et noms alternatifs relatifs à SIRT2

Sirtuin 2 (Sirt2), sirtuin 2 (SIRT2), sirtuin 2 S homeolog (sirt2.S), NAD-dependent deacetylase sirtuin 2 homolog (Sirt2), sirtuin 2 (SRT2), sirtuin 2 (sirt2), sirtuin 2 (Sirt2), sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae) (sirt2), 5730427M03Rik, AtSRT2, BmSirt2, CG5085, D.mel2, Dmel\\CG5085, dSIRT2, sir2, SIR2, SIR2L, Sir2l, SIR2L2, SIRT2, Sirt2, SIRTUIN 2, sirtuin 2, T2K12.8, wu:fb57d05, zgc:55966, zgc:77003

Protein level used designations for SIRT2

  • CG5085-PA
  • Sirt2-PA
  • sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae)
  • sirtuin 2
  • NAD-dependent deacetylase SIRT2
  • NAD-dependent deacetylase sirtuin-2
  • histone NADC
  • silent information regulator 2
  • nicotinamide adenine dinucleotide-dependent histone deacetylase
  • NAD-dependent deacetylase sirtuin 2 homolog
  • NAD-dependent protein deacetylase sirtuin-2
  • SIR2-like protein 2
  • regulatory protein SIR2 homolog 2
  • sir2-related protein type 2
  • sirtuin type 2
  • sirtuin-like protein 2
  • mSIR2L2
  • silent mating type information regulation 2, (S.cerevisiae, homolog)-like; sirtuin 2
  • 5E5 antigen
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