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SIRT3 Produits

(Sirtuin 3 (SIRT3))

Catégories

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined\; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq, Jul 2008].

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Catégories SIRT3 en vedette

SIRT3 Anticorps

High quality antibodies with extensive validation data.

SIRT3 Kits ELISA

Reliable ELISA kits for a wide range of species.

SIRT3 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SIRT3 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (11)
  • (5)
N° du produit ABIN390178
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP
Validations
  • (1)
  • (6)
N° du produit ABIN6147792
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (2)
  • (5)
N° du produit ABIN652184
Quantité 200 μL
Fiche technique Fiche technique

SIRT3 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6970232
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6974831
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6959491
Quantité 96 tests
Fiche technique Fiche technique

SIRT3 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
N° du produit ABIN1320045
Quantité 25 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7125107
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1320046
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits SIRT3

Nyárády, Turai, Funke, Györgyi, Makai, Prémusz, Bódis, Sulyok: "Effects of perinatal factors on sirtuin 3, 8-hydroxy-2'- deoxyguanosine, brain-derived neurotrophic factor and serotonin in cord blood and early breast milk: an observational study." dans: International breastfeeding journal, Vol. 15, Issue 1, pp. 57, (2020) (PubMed).

Rezaei, Keshtzar, Khodayar, Javadipour: "SirT3 regulates diabetogenic effects caused by arsenic: An implication for mitochondrial complex II modification." dans: Toxicology letters, Vol. 301, pp. 24-33, (2019) (PubMed).

Li, Chen, Yang, He, He, Xia, Zhang, Xiang: "Single-walled carbon nanohorn aggregates promotes mitochondrial dysfunction-induced apoptosis in hepatoblastoma cells by targeting SIRT3." dans: International journal of oncology, Vol. 53, Issue 3, pp. 1129-1137, (2018) (PubMed).

Schwab, Sison, Meade, Broniowska, Corbett, Ebert: "Decreased Sirtuin Deacetylase Activity in LRRK2 G2019S iPSC-Derived Dopaminergic Neurons." dans: Stem cell reports, Vol. 9, Issue 6, pp. 1839-1852, (2018) (PubMed).

Xu, Gao, Zhang, Wei, Chen, Dai, Zeng, Zhao: "SIRT1/3 Activation by Resveratrol Attenuates Acute Kidney Injury in a Septic Rat Model." dans: Oxidative medicine and cellular longevity, Vol. 2016, pp. 7296092, (2017) (PubMed).

Vidimar, Gius, Chakravarti, Bulun, Wei, Kim: "Dysfunctional MnSOD leads to redox dysregulation and activation of prosurvival AKT signaling in uterine leiomyomas." dans: Science advances, Vol. 2, Issue 11, pp. e1601132, (2016) (PubMed).

Chen, Liu, Li, Wang, Liu, Li, Zhang, Bu: "Mouse SIRT3 attenuates hypertrophy-related lipid accumulation in the heart through the deacetylation of LCAD." dans: PLoS ONE, Vol. 10, Issue 3, pp. e0118909, (2015) (PubMed).

Takumida, Takumida, Katagiri, Anniko: "Localization of sirtuins (SIRT1-7) in the aged mouse inner ear." dans: Acta oto-laryngologica, pp. 1-12, (2015) (PubMed).

Wei, Zhou, Qiao, Ni, Li, You, Guo, Lu: "Oroxylin A inhibits glycolysis-dependent proliferation of human breast cancer via promoting SIRT3-mediated SOD2 transcription and HIF1α destabilization." dans: Cell death & disease, Vol. 6, pp. e1714, (2015) (PubMed).

Pfleger, He, Abdellatif: "Mitochondrial complex II is a source of the reserve respiratory capacity that is regulated by metabolic sensors and promotes cell survival." dans: Cell death & disease, Vol. 6, pp. e1835, (2015) (PubMed).

Synonymes et noms alternatifs relatifs à SIRT3

sirtuin 3 (sirt3), sirtuin 3 (SIRT3), sirtuin 3 (Sirt3), 2310003L23Rik, AI848213, SIR2L3, Sir2l3, sirtuin, zgc:158774

Protein level used designations for SIRT3

  • sirtuin 3
  • sirtuin
  • NAD-dependent deacetylase sirtuin-3, mitochondrial
  • NAD-dependent protein deacetylase sirtuin-3, mitochondrial
  • SIR2-like protein 3
  • mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase
  • regulatory protein SIR2 homolog 3
  • silent mating type information regulation 2, S.cerevisiae, homolog 3
  • sir2-like 3
  • sirtuin type 3
  • SIRT3 mitochondrial
  • NAD-dependent deacetylase sirtuin-3
  • NAD-dependent protein deacetylase sirtuin-3
  • SIRT3L mitochondrial
  • mSIR2L3
  • mitochondrial protein lysine deacetylase
  • silent mating type information regulation 2, (S.cerevisiae, homolog)-like 3
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