SIRT6 Produits
(Sirtuin 6 (SIRT6))
Catégories
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined\; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jul 2010].
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Catégories SIRT6 en vedette
SIRT6 Anticorps
High quality antibodies with extensive validation data.
SIRT6 Kits ELISA
Reliable ELISA kits for a wide range of species.
SIRT6 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
SIRT6 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (5)
N° du produit
ABIN7437191
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, ICC, FACS
Validations
- (5)
N° du produit
ABIN5542442
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Monkey, Mouse, Rat
Application
WB, IP, IF
Validations
- (3)
N° du produit
ABIN6241508
Quantité
100 μL
Fiche technique
Fiche technique
SIRT6 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6959496
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6959497
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
N° du produit
ABIN5593053
Quantité
96 tests
Fiche technique
Fiche technique
SIRT6 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
N° du produit
ABIN1320053
Quantité
25 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7125110
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1320054
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits SIRT6
: "Protective effects of SIRT6 against lipopolysaccharide (LPS) are mediated by deacetylation of Ku70." dans: Molecular immunology, Vol. 101, pp. 312-318, (2019) (PubMed).: "SIRT6 Depletion Sensitizes Human Hepatoma Cells to Chemotherapeutics by Downregulating MDR1 Expression." dans: Frontiers in pharmacology, Vol. 9, pp. 194, (2018) (PubMed).
: "SIRT7 is a histone desuccinylase that functionally links to chromatin compaction and genome stability." dans: Nature communications, Vol. 7, pp. 12235, (2018) (PubMed).
: "Downregulation of SIRT6 is associated with poor prognosis in patients with non-small cell lung cancer." dans: The Journal of international medical research, Vol. 46, Issue 4, pp. 1517-1527, (2018) (PubMed).
: "Deacetylation of Ku70 by SIRT6 attenuates Bax-mediated apoptosis in hepatocellular carcinoma." dans: Biochemical and biophysical research communications, Vol. 485, Issue 4, pp. 713-719, (2017) (PubMed).
: "SIRT6 Overexpression Potentiates Apoptosis Evasion in Hepatocellular Carcinoma via BCL2-Associated X Protein-Dependent Apoptotic Pathway." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 22, Issue 13, pp. 3372-82, (2016) (PubMed).
: "Cyclic AMP Mimics the Anti-ageing Effects of Calorie Restriction by Up-Regulating Sirtuin." dans: Scientific reports, Vol. 5, pp. 12012, (2015) (PubMed).
: "SIRT6 expression is associated with poor prognosis and chemosensitivity in patients with non-small cell lung cancer." dans: Journal of surgical oncology, Vol. 112, Issue 2, pp. 231-7, (2015) (PubMed).
: "Epigenetic modulation of chronic anxiety and pain by histone deacetylation." dans: Molecular psychiatry, Vol. 20, Issue 10, pp. 1219-31, (2015) (PubMed).
: "Biochemical characterization of sirtuin 6 in the brain and its involvement in oxidative stress response." dans: Neurochemical research, Vol. 40, Issue 1, pp. 59-69, (2015) (PubMed).
Synonymes et noms alternatifs relatifs à SIRT6
sirtuin 6 (Sirt6), sirtuin 6 (SIRT6), sirtuin 6 S homeolog (sirt6.S), sirtuin 6 (sirt6), 2810449N18Rik, AI043036, Sir2l6, SIR2L6, zgc:86729Protein level used designations for SIRT6
- NAD-dependent deacetylase sirtuin-6
- NAD-dependent protein deacetylase sirtuin-6
- SIR2-like protein 6
- regulatory protein SIR2 homolog 6
- sir2-related protein type 6
- sirtuin type 6
- sirtuin (silent mating type information regulation 2 homolog) 6
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