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SLC11A2 Produits

(Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 2 (SLC11A2))
This gene encodes a member of the solute carrier family 11 protein family. The product of this gene transports divalent metals and is involved in iron absorption. Mutations in this gene are associated with hypochromic microcytic anemia with iron overload. A related solute carrier family 11 protein gene is located on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2010].

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Catégories SLC11A2 en vedette

SLC11A2 Anticorps

High quality antibodies with extensive validation data.

SLC11A2 Kits ELISA

Reliable ELISA kits for a wide range of species.

SLC11A2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SLC11A2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Chicken, Human, Mouse, Rat
Application ELISA, WB, IF (cc), IF (p), IHC (p), FACS, IHC (fro)
Validations
  • (2)
  • (3)
N° du produit ABIN701065
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Mouse, Rat
Application WB, IF
Validations
  • (2)
  • (3)
N° du produit ABIN657723
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, WB, IHC (p)
Validations
  • (4)
  • (3)
N° du produit ABIN562043
Quantité 100 μg
Fiche technique Fiche technique

SLC11A2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6959559
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6970292
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6970293
Quantité 96 tests
Fiche technique Fiche technique

SLC11A2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1320123
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7406986
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7406983
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits SLC11A2

Pandur, Varga, Tamási, Pap, Nagy, Sipos: "Effect of Inflammatory Mediators Lipopolysaccharide and Lipoteichoic Acid on Iron Metabolism of Differentiated SH-SY5Y Cells Alters in the Presence of BV-2 Microglia." dans: International journal of molecular sciences, Vol. 20, Issue 1, (2019) (PubMed).

Zhang, Li, Zhang, Ge, Han, Sun, Ding, Lu, Hu: "Deletion of Kir6.2/SUR1 potassium channels rescues diminishing of DA neurons via decreasing iron accumulation in PD." dans: Molecular and cellular neurosciences, Vol. 92, pp. 164-176, (2019) (PubMed).

Zhang, Li, Liao, Zhang, Lu, Luo: "Effect of iron source on iron absorption and gene expression of iron transporters in the ligated duodenal loops of broilers." dans: Journal of animal science, Vol. 95, Issue 4, pp. 1587-1597, (2017) (PubMed).

Zhang, Zhao, Chang, Zhang, Chu, Zhang, Liu, Guo, Wang, Gao, Zhang, Chu: "Calcium channel blockers ameliorate iron overload-associated hepatic fibrosis by altering iron transport and stellate cell apoptosis." dans: Toxicology and applied pharmacology, Vol. 301, pp. 50-60, (2016) (PubMed).

Montalbetti, Simonin, Simonin, Awale, Reymond, Hediger: "Discovery and characterization of a novel non-competitive inhibitor of the divalent metal transporter DMT1/SLC11A2." dans: Biochemical pharmacology, Vol. 96, Issue 3, pp. 216-24, (2015) (PubMed).

Montalbetti, Simonin, Dalghi, Kovacs, Hediger: "Development and Validation of a Fast and Homogeneous Cell-Based Fluorescence Screening Assay for Divalent Metal Transporter 1 (DMT1/SLC11A2) Using the FLIPR Tetra." dans: Journal of biomolecular screening, Vol. 19, Issue 6, pp. 900-908, (2014) (PubMed).

Scheers, Almgren, Sandberg: "Proposing a Caco-2/HepG2 cell model for in vitro iron absorption studies." dans: The Journal of nutritional biochemistry, Vol. 25, Issue 7, pp. 710-5, (2014) (PubMed).

Scibior, Adamczyk, Gołębiowska, Niedźwiecka, Fornal et al.: "The influence of combined magnesium and vanadate administration on the level of some elements in selected rat organs: V-Mg interactions and the role of iron-essential protein (DMT-1) in the mechanism ..." dans: Metallomics : integrated biometal science, Vol. 6, Issue 4, pp. 907-20, (2014) (PubMed).

Mondal, Schilling, Folger, Steibel, Buchnick, Zalman, Ireland, Meidan, Smith: "Deciphering the luteal transcriptome: potential mechanisms mediating stage-specific luteolytic response of the corpus luteum to prostaglandin F??." dans: Physiological genomics, Vol. 43, Issue 8, pp. 447-56, (2011) (PubMed).

Ramachandran, Tran, Klebba-Faerber, Kardinal, Whetton, Tamura: "An ataxia-telangiectasia-mutated (ATM) kinase mediated response to DNA damage down-regulates the mRNA-binding potential of THOC5." dans: RNA (New York, N.Y.), Vol. 17, Issue 11, pp. 1957-66, (2011) (PubMed).

Synonymes et noms alternatifs relatifs à SLC11A2

solute carrier family 11 member 2 (SLC11A2), solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 (Slc11a2), solute carrier family 11 member 2 (Slc11a2), NRAMP metal ion transporter 2 (NRAMP2), manganese transport protein (NRAMP2), metal transporter Nramp2 (LOC9327403), solute carrier family 11 member 2 (slc11a2), solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 (slc11a2), ATNRAMP2, cb426, DCT1, dct1, DMT1, Dmt1, dmt1, F8G22.4, F8G22_4, fa07b10, mk, NRAMP2, Nramp2, nramp2, NRAMP metal ion transporter 2, SLC11A2, van, wu:fa07b10, zgc:136699

Protein level used designations for SLC11A2

  • DMT-1
  • NRAMP 2
  • divalent cation transporter 1
  • natural resistance-associated macrophage protein 2
  • solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
  • divalent metal transporter 1
  • microcytic anemia, viable anaemia
  • Solute carrier family 11 member 2 (natural resistance-associated macrophage protein 2)
  • manganese transport protein
  • NRAMP2
  • cdy
  • chardonnay
  • nramp
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