SLC12A6 Produits
(Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 6 (SLC12A6))
Catégories
This gene is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy. [provided by RefSeq, Jul 2008].
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Catégories SLC12A6 en vedette
SLC12A6 Anticorps
High quality antibodies with extensive validation data.
SLC12A6 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
SLC12A6 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
N° du produit
ABIN656316
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (4)
- (1)
N° du produit
ABIN564298
Quantité
50 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
N° du produit
ABIN238578
Quantité
100 μg
Fiche technique
Fiche technique
SLC12A6 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1320131
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7394462
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3118929
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits SLC12A6
: "The K-Cl cotransporter KCC3 as an independent prognostic factor in human esophageal squamous cell carcinoma." dans: BioMed research international, Vol. 2014, pp. 936401, (2014) (PubMed).: "Potassium-chloride cotransporter 3 interacts with Vav2 to synchronize the cell volume decrease response with cell protrusion dynamics." dans: PLoS ONE, Vol. 8, Issue 5, pp. e65294, (2013) (PubMed).
: "Loss of neuronal potassium/chloride cotransporter 3 (KCC3) is responsible for the degenerative phenotype in a conditional mouse model of hereditary motor and sensory neuropathy associated with ..." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 11, pp. 3865-76, (2012) (PubMed).
: "Transit defect of potassium-chloride Co-transporter 3 is a major pathogenic mechanism in hereditary motor and sensory neuropathy with agenesis of the corpus callosum." dans: The Journal of biological chemistry, Vol. 286, Issue 32, pp. 28456-65, (2011) (PubMed).
: "HMSN/ACC truncation mutations disrupt brain-type creatine kinase-dependant activation of K+/Cl- co-transporter 3." dans: Human molecular genetics, Vol. 17, Issue 17, pp. 2703-11, (2008) (PubMed).
: "Homooligomeric and heterooligomeric associations between K+-Cl- cotransporter isoforms and between K+-Cl- and Na+-K+-Cl- cotransporters." dans: The Journal of biological chemistry, Vol. 282, Issue 25, pp. 18083-93, (2007) (PubMed).
Synonymes et noms alternatifs relatifs à SLC12A6
solute carrier family 12, member 6 (Slc12a6), solute carrier family 12 member 6 (SLC12A6), 9530023I19Rik, ACCPN, gaxp, Kcc3, KCC3, KCC3A, KCC3BProtein level used designations for SLC12A6
- solute carrier family 12 member 6
- furosemide-sensitive KCl cotransporter 3
- K-Cl cotransporter 3
- electroneutral potassium-chloride cotransporter 3
- potassium chloride cotransporter 3
- potassium chloride cotransporter KCC3a-S3
- potassium-chloride transporter-3a
- potassium-chloride transporter-3b
- solute carrier family 12 (potassium/chloride transporters), member 6
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