SLC22A1 Produits
(Solute Carrier Family 22 (Organic Cation Transporter), Member 1 (SLC22A1))
Catégories
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter. [provided by RefSeq, Jul 2008].
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Catégories SLC22A1 en vedette
SLC22A1 Anticorps
High quality antibodies with extensive validation data.
SLC22A1 Kits ELISA
Reliable ELISA kits for a wide range of species.
SLC22A1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
SLC22A1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF
Validations
- (3)
N° du produit
ABIN7075663
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, FACS
Validations
- (3)
- (2)
N° du produit
ABIN969400
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
N° du produit
ABIN7170131
Quantité
100 μg
Fiche technique
Fiche technique
SLC22A1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Analytical Method
Qualitative DNA-Binding ELISA
Validations
N° du produit
ABIN5648541
Quantité
96 tests
Fiche technique
Fiche technique
SLC22A1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7423393
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3109816
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3131351
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits SLC22A1
: "Organic cation transporter 1 (OCT1) is involved in pentamidine transport at the human and mouse blood-brain barrier (BBB)." dans: PLoS ONE, Vol. 12, Issue 3, pp. e0173474, (2017) (PubMed).: "Organic anion transporting polypeptide 1B3 can form homo- and hetero-oligomers." dans: PLoS ONE, Vol. 12, Issue 6, pp. e0180257, (2017) (PubMed).
: "Fine Mapping and Functional Analysis Reveal a Role of SLC22A1 in Acylcarnitine Transport." dans: American journal of human genetics, Vol. 101, Issue 4, pp. 489-502, (2017) (PubMed).
: "The human organic cation transporter OCT1 mediates high affinity uptake of the anticancer drug daunorubicin." dans: Scientific reports, Vol. 6, pp. 20508, (2016) (PubMed).
: "Global genetic analyses reveal strong inter-ethnic variability in the loss of activity of the organic cation transporter OCT1." dans: Genome medicine, Vol. 7, Issue 1, pp. 56, (2015) (PubMed).
: "The cell line NCl-H441 is a useful in vitro model for transport studies of human distal lung epithelial barrier." dans: Molecular pharmaceutics, Vol. 11, Issue 3, pp. 995-1006, (2014) (PubMed).
: "Common drugs inhibit human organic cation transporter 1 (OCT1)-mediated neurotransmitter uptake." dans: Drug metabolism and disposition: the biological fate of chemicals, Vol. 42, Issue 6, pp. 990-5, (2014) (PubMed).
: "OCT1 (SLC22A1) R61C polymorphism and response to imatinib treatment in chronic myeloid leukemia patients." dans: Leukemia & lymphoma, Vol. 49, Issue 11, pp. 2222-3, (2008) (PubMed).
: "Constitutive overexpression of P-glycoprotein, rather than breast cancer resistance protein or organic cation transporter 1, contributes to acquisition of imatinib-resistance in K562 cells." dans: Pharmaceutical research, Vol. 25, Issue 4, pp. 827-35, (2008) (PubMed).
: "Effective dasatinib uptake may occur without human organic cation transporter 1 (hOCT1): implications for the treatment of imatinib-resistant chronic myeloid leukemia." dans: Blood, Vol. 112, Issue 8, pp. 3348-54, (2008) (PubMed).
Synonymes et noms alternatifs relatifs à SLC22A1
solute carrier family 22 member 1 (SLC22A1), solute carrier family 22 (organic cation transporter), member 1 (Slc22a1), solute carrier family 22 member 1 (Slc22a1), solute carrier family 22 member 2-like (LOC421584), HOCT1, Lx1, OCT1, Oct1, oct1_cds, Orct, Orct1, Roct1, SLC22A1, SLC22A2Protein level used designations for SLC22A1
- solute carrier family 22 member 1
- solute carrier family 22 (organic cation transporter), member 1
- solute carrier family 22 member 1-like
- pOCT1
- organic cation transporter 1
- mOCT1
- solute carrier family 22, member 1
- solute carrier family 22 (organic cation transporter), member 2
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