SLC22A12 Produits
(Solute Carrier Family 22 (Organic Anion/urate Transporter), Member 12 (SLC22A12))
Catégories
The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013].
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Catégories SLC22A12 en vedette
SLC22A12 Anticorps
High quality antibodies with extensive validation data.
SLC22A12 Kits ELISA
Reliable ELISA kits for a wide range of species.
SLC22A12 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
SLC22A12 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
- (3)
N° du produit
ABIN530376
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
N° du produit
ABIN7192423
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB
Validations
- (1)
- (2)
N° du produit
ABIN1682756
Quantité
100 μg
Fiche technique
Fiche technique
SLC22A12 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6959579
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6959580
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6232809
Quantité
96 tests
Fiche technique
Fiche technique
SLC22A12 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1320195
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1320194
Quantité
25 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7406998
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits SLC22A12
: "Phloretin attenuates hyperuricemia-induced endothelial dysfunction through co-inhibiting inflammation and GLUT9-mediated uric acid uptake." dans: Journal of cellular and molecular medicine, Vol. 21, Issue 10, pp. 2553-2562, (2018) (PubMed).: "Coevolution of URAT1 and Uricase during Primate Evolution: Implications for Serum Urate Homeostasis and Gout." dans: Molecular biology and evolution, Vol. 33, Issue 9, pp. 2193-200, (2016) (PubMed).
: "OIT3 deficiency impairs uric acid reabsorption in renal tubule." dans: FEBS letters, Vol. 586, Issue 6, pp. 760-5, (2012) (PubMed).
: "Sucrose induces fatty liver and pancreatic inflammation in male breeder rats independent of excess energy intake." dans: Metabolism: clinical and experimental, Vol. 60, Issue 9, pp. 1259-70, (2011) (PubMed).
: "The SLC22 drug transporter family." dans: Pflügers Archiv : European journal of physiology, Vol. 447, Issue 5, pp. 666-76, (2004) (PubMed).
: "[Molecular biology of urate transporter]." dans: Seikagaku. The Journal of Japanese Biochemical Society, Vol. 76, Issue 2, pp. 101-10, (2004) (PubMed).
: "The multivalent PDZ domain-containing protein PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C terminus." dans: The Journal of biological chemistry, Vol. 279, Issue 44, pp. 45942-50, (2004) (PubMed).
: "Two male siblings with hereditary renal hypouricemia and exercise-induced ARF." dans: American journal of kidney diseases : the official journal of the National Kidney Foundation, Vol. 42, Issue 6, pp. 1287-92, (2003) (PubMed).
: "Clinical and molecular analysis of patients with renal hypouricemia in Japan-influence of URAT1 gene on urinary urate excretion." dans: Journal of the American Society of Nephrology : JASN, Vol. 15, Issue 1, pp. 164-73, (2003) (PubMed).
Synonymes et noms alternatifs relatifs à SLC22A12
solute carrier family 22 (organic anion/cation transporter), member 12 (Slc22a12), solute carrier family 22 member 12 (SLC22A12), solute carrier family 22 member 12 (Slc22a12), AI987855, OAT4L, Rst, RST, Slc22al2, URAT1Protein level used designations for SLC22A12
- renal-specific transporter
- solute carrier family 22 (organic cation transporter)-like 2
- solute carrier family 22 member 12
- urate anion exchanger 1
- organic anion transporter 4-like protein
- solute carrier family 22 (organic anion/cation transporter), member 12
- urate transporter 1
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