SLC46A1 Produits
(Solute Carrier Family 46 (Folate Transporter), Member 1 (SLC46A1))
Catégories
This gene encodes a transmembrane proton-coupled folate transporter protein that facilitates the movement of folate and antifolate substrates across cell membranes, optimally in acidic pH environments. This protein is also expressed in the brain and choroid plexus where it transports folates into the central nervous system. This protein further functions as a heme transporter in duodenal enterocytes, and potentially in other tissues like liver and kidney. Its localization to the apical membrane or cytoplasm of intestinal cells is modulated by dietary iron levels. Mutations in this gene are associated with autosomal recessive hereditary folate malabsorption (HFM) disease. HFM is characterized by folate deficiency due to reduced intestinal folate absorption and subsequent anemia, hypoimmunoglobulinemia, and recurrent infections. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2011].
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Catégories SLC46A1 en vedette
SLC46A1 Anticorps
High quality antibodies with extensive validation data.
SLC46A1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
SLC46A1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
ELISA, IHC
Validations
- (1)
N° du produit
ABIN7166588
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
N° du produit
ABIN768542
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Dog, Guinea Pig, Hamster, Horse, Human, Monkey, Mouse, Rat
Application
WB
Validations
- (1)
N° du produit
ABIN6741754
Quantité
100 μL
Fiche technique
Fiche technique
SLC46A1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
N° du produit
ABIN1330511
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3117461
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3123723
Quantité
1 mg
Fiche technique
Fiche technique
Synonymes et noms alternatifs relatifs à SLC46A1
solute carrier family 46 member 1 (SLC46A1), solute carrier family 46 (folate transporter), member 1 (slc46a1), solute carrier family 46 member 1 (Slc46a1), solute carrier family 46, member 1 (Slc46a1), 1110002C08Rik, D11Ertd18e, G21, HCP1, PCFT, Pcft, RGD1309472, TRPEProtein level used designations for SLC46A1
- solute carrier family 46, member 1
- solute carrier family 46 (folate transporter), member 1
- proton-coupled folate transporter-like
- heme carrier protein 1
- proton-coupled folate transporter
- PCFT/HCP1
- retinal pigment epithelilum transporter
- retinal pigment epithelium transporter
- solute carrier family 46 member 1
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