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SLC7A11 Produits

(Solute Carrier Family 7, (Cationic Amino Acid Transporter, Y+ System) Member 11 (SLC7A11))

Catégories

This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011].

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Catégories SLC7A11 en vedette

SLC7A11 Anticorps

High quality antibodies with extensive validation data.

SLC7A11 Kits ELISA

Reliable ELISA kits for a wide range of species.

SLC7A11 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SLC7A11 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application ELISA, IF
Validations
  • (10)
N° du produit ABIN190899
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, ELISA, FACS, FM, IP
Validations
  • (4)
N° du produit ABIN6655336
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB
Validations
  • (4)
N° du produit ABIN7043751
Quantité 25 μL
Fiche technique Fiche technique

SLC7A11 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6970357
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6959627
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6959628
Quantité 96 tests
Fiche technique Fiche technique

SLC7A11 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7491739
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1320520
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN7092733
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits SLC7A11

Greenwood, McCormick, Gendron, Glaser, Pereira, Maddocks, Sander, Zhang, Koglin, Lythgoe, Årstad, Hochhauser, Witney: "Measurement of Tumor Antioxidant Capacity and Prediction of Chemotherapy Resistance in Preclinical Models of Ovarian Cancer by Positron Emission Tomography." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 25, Issue 8, pp. 2471-2482, (2019) (PubMed).

Isobe, Kataoka, Endo, Moriyama, Okazaki, Tsuchihashi, Katsumata, Yamamoto, Shirakawa, Yoshida, Shimoda, Chiba, Masuko, Hakamata, Kobayashi, Saya, Fukuda, Sano: "Endothelial-Mesenchymal Transition Drives Expression of CD44 Variant and xCT in Pulmonary Hypertension." dans: American journal of respiratory cell and molecular biology, (2019) (PubMed).

Ungard, Linher-Melville, Nashed, Sharma, Wen, Singh: "xCT knockdown in human breast cancer cells delays onset of cancer-induced bone pain." dans: Molecular pain, Vol. 15, pp. 1744806918822185, (2019) (PubMed).

Li, Chen, Lan, He, Chen, Wang, Liu, Li, Cheng, Liu, Sun, Wan, Chen, Peng, Li, Zhang, Jing, Huang, Wang, Wang, Jiang, Zha, Chen, Zhang: "mTOR-dependent upregulation of xCT blocks melanin synthesis and promotes tumorigenesis." dans: Cell death and differentiation, (2019) (PubMed).

Pitman, Alluri, Kristian, Aarnes, Lyng, Riss, Malinen: "Influx rate of 18F-fluoroaminosuberic acid reflects cystine/glutamate antiporter expression in tumour xenografts." dans: European journal of nuclear medicine and molecular imaging, Vol. 46, Issue 10, pp. 2190-2198, (2019) (PubMed).

Hoehne, James, Alam, Ronald, Schneider, DSouza, Witney, Andrews, Cropper, Behera, Gowrishankar, Ding, Wyss-Coray, Chin, Biswal, Gambhir: "[18F]FSPG-PET reveals increased cystine/glutamate antiporter (xc-) activity in a mouse model of multiple sclerosis." dans: Journal of neuroinflammation, Vol. 15, Issue 1, pp. 55, (2018) (PubMed).

Miladinovic, Ungard, Linher-Melville, Popovic, Singh: "Functional effects of TrkA inhibition on system xC--mediated glutamate release and cancer-induced bone pain." dans: Molecular pain, Vol. 14, pp. 1744806918776467, (2018) (PubMed).

Huang, Lin, Chang, Lei, Ho, Liu, Shyu, Hsieh: "RGS4 deficit in prefrontal cortex contributes to the behaviors related to schizophrenia via system xc--mediated glutamatergic dysfunction in mice." dans: Theranostics, Vol. 8, Issue 17, pp. 4781-4794, (2018) (PubMed).

Mi, Dixit, Warner, Kennard, Scharf, Kessler, Moore, Consoli, Bown, Eugene, Kang, Harrison: "Altered glutamate clearance in ascorbate deficient mice increases seizure susceptibility and contributes to cognitive impairment in APP/PSEN1 mice." dans: Neurobiology of aging, Vol. 71, pp. 241-254, (2018) (PubMed).

Suárez-Pozos, Martínez-Lozada, Méndez-Flores, Guillem, Hernández-Kelly, Castelán, Olivares-Bañuelos, Chi-Castañeda, Najimi, Ortega: "Characterization of the cystine/glutamate antiporter in cultured Bergmann glia cells." dans: Neurochemistry international, (2017) (PubMed).

Synonymes et noms alternatifs relatifs à SLC7A11

solute carrier family 7 member 11 (SLC7A11), solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 (SLC7A11), solute carrier family 7 member 11 (Slc7a11), solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 (Slc7a11), 9930009M05Rik, AI451155, CCBR1, DKFZp468E122, SLC7A11, sut, xCT

Protein level used designations for SLC7A11

  • solute carrier family 7, (cationic amino acid transporter, y+ system) member 11
  • cystine/glutamate transporter
  • solute carrier family 7, member 11
  • Cystine/glutamate transporter
  • cystine/glutamate transporter-like
  • solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
  • amino acid transport system xc-
  • calcium channel blocker resistance protein CCBR1
  • solute carrier family 7 member 11
  • solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
  • cysteine/glutamate transporter
  • sodium independent anionic amino acid transport system
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