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SLC7A8 Produits

(Solute Carrier Family 7 (Amino Acid Transporter, L-Type), Member 8 (SLC7A8))

Catégories

Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Plays an essential role in the reabsorption of neutral amino acids from the epithelial cells to the bloodstream in the kidney (By similarity).

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Catégories SLC7A8 en vedette

SLC7A8 Anticorps

High quality antibodies with extensive validation data.

SLC7A8 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SLC7A8 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, FACS, IHC, IHC (p), IF, IP
Validations
  • (5)
N° du produit ABIN1500960
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, FACS
Validations
  • (2)
N° du produit ABIN6243302
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (2)
N° du produit ABIN525163
Quantité 100 μg
Fiche technique Fiche technique

SLC7A8 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1320534
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1320533
Quantité 25 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3118920
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits SLC7A8

Romanet, Aschenbach, Pieper, Zentek, Htoo, Whelan, Mastrototaro: "Expression of proposed methionine transporters along the gastrointestinal tract of pigs and their regulation by dietary methionine sources." dans: Genes & nutrition, Vol. 16, Issue 1, pp. 14, (2021) (PubMed).

Cicone, Minniti, Oliva, Carideo, Prior, Scopinaro, Giangaspero, Arcella: "Expression of large neutral amino acid transporters LAT1 and LAT2 in medulloblastoma." dans: Brain tumor pathology, Vol. 34, Issue 4, pp. 179-181, (2018) (PubMed).

Balthasar, Stangl, Widhalm, Granitzer, Hengstschläger, Gundacker: "Methylmercury Uptake into BeWo Cells Depends on LAT2-4F2hc, a System L Amino Acid Transporter." dans: International journal of molecular sciences, Vol. 18, Issue 8, (2018) (PubMed).

Hutterer, Ebner, Riemenschneider, Willuweit, McCoy, Egger, Schröder, Wendl, Hellwig, Grosse, Menhart, Proescholdt, Fritsch, Urbach, Stockhammer, Roelcke, Galldiks, Meyer, Langen, Hau, Trinka: "Epileptic Activity Increases Cerebral Amino Acid Transport Assessed by 18F-Fluoroethyl-l-Tyrosine Amino Acid PET: A Potential Brain Tumor Mimic." dans: Journal of nuclear medicine : official publication, Society of Nuclear Medicine, Vol. 58, Issue 1, pp. 129-137, (2016) (PubMed).

Synonymes et noms alternatifs relatifs à SLC7A8

solute carrier family 7 member 8 (SLC7A8), solute carrier family 7 member 8 (Slc7a8), solute carrier family 7 member 8 L homeolog (slc7a8.L), solute carrier family 7 member 8 (slc7a8), solute carrier family 7 (amino acid transporter, L-type), member 8 (SLC7A8), solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 (Slc7a8), solute carrier family 7 (amino acid transporter light chain, L system), member 8b (slc7a8b), 4F2LC-5, AA408822, LAT2, Lat2, lat2, Lat4, LPI-PC1, lpi-pc1, si:ch211-14a17.3, si:zc14a17.3, slc7a8, XAA2

Protein level used designations for SLC7A8

  • L-type amino acid transporter 2
  • integral membrane protein E16H
  • large neutral amino acids transporter small subunit 2
  • solute carrier family 7 (amino acid transporter, L-type), member 8
  • solute carrier family 7 (cationic amino acid transporter, y+ system), member 8
  • cationic amino acid transporter y+ system
  • solute carrier family 7 member 8
  • glycoprotein-associated amino acid transporter LAT2
  • 4F2-LC5
  • mLAT2
  • solute carrier family 8 (cationic amino acid transporter, y+ system), member 7
  • solute carrier family 7 (amino acid transporter light chain, L system), member 8
  • zmp:0000000645
  • zmp:0000000781
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