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SLPI Produits

(Secretory Leukocyte Peptidase Inhibitor (SLPI))
This gene encodes a secreted inhibitor which protects epithelial tissues from serine proteases. It is found in various secretions including seminal plasma, cervical mucus, and bronchial secretions, and has affinity for trypsin, leukocyte elastase, and cathepsin G. Its inhibitory effect contributes to the immune response by protecting epithelial surfaces from attack by endogenous proteolytic enzymes\; the protein is also thought to have broad-spectrum anti-biotic activity. [provided by RefSeq, Jul 2008].

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Catégories SLPI en vedette

SLPI Anticorps

High quality antibodies with extensive validation data.

SLPI Kits ELISA

Reliable ELISA kits for a wide range of species.

SLPI Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SLPI recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (5)
N° du produit ABIN7433429
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
N° du produit ABIN7144333
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (3)
N° du produit ABIN520270
Quantité 100 μg
Fiche technique Fiche technique

SLPI recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6959320
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6959321
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6970066
Quantité 96 tests
Fiche technique Fiche technique

SLPI recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7275627
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7275628
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
N° du produit ABIN1320577
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits SLPI

Mosedale, Kim, Brock, Roth, Wiltshire, Eaddy, Keele, Corty, Xie, Valdar, Watkins: "Editor's Highlight: Candidate Risk Factors and Mechanisms for Tolvaptan-Induced Liver Injury Are Identified Using a Collaborative Cross Approach." dans: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 156, Issue 2, pp. 438-454, (2018) (PubMed).

Olewicz-Gawlik, Trzybulska, Graniczna, Kuznar-Kaminska, Katulska, Batura-Gabryel, Frydrychowicz, Danczak-Pazdrowska, Mozer-Lisewska: "Serum alarm antiproteases in systemic sclerosis patients." dans: Human immunology, Vol. 78, Issue 9, pp. 559-564, (2018) (PubMed).

Svensson, Aidoukovitch, Anders, Jönsson, Nebel, Nilsson: "Secretory leukocyte protease inhibitor regulates human periodontal ligament cell production of pro-inflammatory cytokines." dans: Inflammation research : official journal of the European Histamine Research Society ... [et al.], Vol. 66, Issue 9, pp. 823-831, (2018) (PubMed).

Sayers, Brooks, Sayers, Chertov: "Increased secretory leukocyte protease inhibitor (SLPI) production by highly metastatic mouse breast cancer cells." dans: PLoS ONE, Vol. 9, Issue 8, pp. e104223, (2015) (PubMed).

Nikolakopoulou, Dutta, Chen, Miller, Trapp: "Activated microglia enhance neurogenesis via trypsinogen secretion." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 21, pp. 8714-9, (2013) (PubMed).

Subramaniyam, Hollander, Westin, Erjefält, Stevens, Janciauskiene: "Secretory leukocyte protease inhibitor inhibits neutrophil apoptosis." dans: Respirology (Carlton, Vic.), Vol. 16, Issue 2, pp. 300-7, (2011) (PubMed).

Cheng, Wang, Huang, Liang, Lin, Hsueh, Wu, Chen, Yu, Lin, Lin: "Overexpression of a secretory leukocyte protease inhibitor in human gastric cancer." dans: International journal of cancer. Journal international du cancer, Vol. 123, Issue 8, pp. 1787-96, (2008) (PubMed).

Bingle, Cross, High, Wallace, Rassl, Yuan, Hellstrom, Campos, Bingle: "WFDC2 (HE4): a potential role in the innate immunity of the oral cavity and respiratory tract and the development of adenocarcinomas of the lung." dans: Respiratory research, Vol. 7, pp. 61, (2006) (PubMed).

Jana, Gray, Shugars: "Human immunodeficiency virus type 1 stimulates the expression and production of secretory leukocyte protease inhibitor (SLPI) in oral epithelial cells: a role for SLPI in innate mucosal immunity." dans: Journal of virology, Vol. 79, Issue 10, pp. 6432-40, (2005) (PubMed).

Taggart, Cryan, Weldon, Gibbons, Greene, Kelly, Low, Oneill, McElvaney: "Secretory leucoprotease inhibitor binds to NF-kappaB binding sites in monocytes and inhibits p65 binding." dans: The Journal of experimental medicine, Vol. 202, Issue 12, pp. 1659-68, (2005) (PubMed).

Synonymes et noms alternatifs relatifs à SLPI

secretory leukocyte peptidase inhibitor (SLPI), secretory leukocyte peptidase inhibitor (Slpi), antileukoproteinase (LOC102174044), ALK1, ALP, BLPI, ckpi, HUSI, HUSI-I, MATN4, MPI, SLPI, WAP4, WFDC4

Protein level used designations for SLPI

  • HUSI-1
  • WAP four-disulfide core domain protein 4
  • antileukoproteinase
  • mucus proteinase inhibitor
  • protease inhibitor WAP4
  • secretory leukocyte protease inhibitor (antileukoproteinase)
  • seminal proteinase inhibitor
  • ALP
  • secretory leukocyte protease inhibitor
  • matrilin 4
  • secretory leukocyte peptidase inhibitor
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