SMAD2 Produits
(SMAD, Mothers Against DPP Homolog 2 (SMAD2))
Catégories
The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors. This protein can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012].
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Catégories SMAD2 en vedette
SMAD2 Anticorps
High quality antibodies with extensive validation data.
SMAD2 Kits ELISA
Reliable ELISA kits for a wide range of species.
SMAD2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
SMAD2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (1)
- (6)
N° du produit
ABIN517619
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (6)
N° du produit
ABIN7160228
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF
Validations
- (7)
N° du produit
ABIN7265256
Quantité
200 μL
Fiche technique
Fiche technique
SMAD2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6959520
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6959523
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6970250
Quantité
96 tests
Fiche technique
Fiche technique
SMAD2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1320595
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7125122
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN667736
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits SMAD2
: "The TGF-β1 pathway is early involved in neurogenic bladder fibrosis of juvenile rats." dans: Pediatric research, Vol. 90, Issue 4, pp. 759-767, (2022) (PubMed).: "Disruption of the mouse Bmal1 locus promotes heterotopic ossification with aging via TGF-beta/BMP signaling." dans: Journal of bone and mineral metabolism, Vol. 40, Issue 1, pp. 40-55, (2022) (PubMed).
: "Extracellular vesicles derived from mesenchymal stem cells prevent skin fibrosis in the cGVHD mouse model by suppressing the activation of macrophages and B cells immune response." dans: International immunopharmacology, Vol. 84, pp. 106541, (2021) (PubMed).
: "Use of a PTFE Micro-Bioreactor to Promote 3D Cell Rearrangement and Maintain High Plasticity in Epigenetically Erased Fibroblasts." dans: Stem cell reviews, Vol. 15, Issue 1, pp. 82-92, (2019) (PubMed).
: "Snail regulates BMP and TGFβ pathways to control the differentiation status of glioma-initiating cells." dans: Oncogene, Vol. 37, Issue 19, pp. 2515-2531, (2019) (PubMed).
: "Gamma synuclein is a novel Twist1 target that promotes TGF-β-induced cancer cell migration and invasion." dans: Cell death & disease, Vol. 9, Issue 6, pp. 625, (2018) (PubMed).
: "Isoviolanthin Extracted from Dendrobium officinale Reverses TGF-β1-Mediated Epithelial⁻Mesenchymal Transition in Hepatocellular Carcinoma Cells via Deactivating the TGF-β/Smad and PI3K/Akt/mTOR ..." dans: International journal of molecular sciences, Vol. 19, Issue 6, (2018) (PubMed).
: "Effects of cholecalciferol cholesterol emulsion on renal fibrosis and aquaporin 2 and 4 in mice with unilateral ureteral obstruction." dans: Biomedicine & pharmacotherapy, Vol. 102, pp. 633-638, (2018) (PubMed).
: "Baicalin inhibits pressure overload-induced cardiac fibrosis through regulating AMPK/TGF-β/Smads signaling pathway." dans: Archives of biochemistry and biophysics, Vol. 640, pp. 37-46, (2018) (PubMed).
: "IFI16 is involved in HBV-associated acute-on-chronic liver failure inflammation." dans: BMC gastroenterology, Vol. 18, Issue 1, pp. 61, (2018) (PubMed).
Synonymes et noms alternatifs relatifs à SMAD2
SMAD family member 2 (SMAD2), SMAD family member 2-Z (SMAD2Z), SMAD family member 2 (smad2), SMAD family member 2 S homeolog (smad2.S), SMAD family member 2 (Smad2), 7120426M23Rik, fj43c06, hMAD-2, hmad-2, hSMAD2, hsmad2, JV18, jv18, JV18-1, jv18-1, MADH2, madh2, Madh2, MAD homolog 2, MADR2, madr2, Madr2, mMad2, Mothers against DPP homolog 2, smad-2, Smad-2, SMAD 2, Smad2, wu:fj43c06, Xmad2, XSmad2Protein level used designations for SMAD2
- MAD homolog 2
- SMAD, mothers against DPP homolog 2
- Sma- and Mad-related protein 2
- mother against DPP homolog 2
- mothers against decapentaplegic homolog 2
- SMAD 2
- mothers against DPP homolog 2
- mothers against decapentaplegic-like 2
- MAD (mothers against decapentaplegic, Drosophila) homolog 2
- SMA- and MAD-related protein 2
- SMAD family member 2
- Smad 2
- mad-related protein 2
- LOW QUALITY PROTEIN: mothers against decapentaplegic homolog 2
Avez-vous cherché autre chose?
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- SMAGP
- Small Cajal Body-Specific RNA 22
- Small Nuclear Ribonucleoprotein Polypeptide A
- Small Nuclear RNA Activating Complex, Polypeptide 1, 43kDa
- Small Proline-Rich Protein 2B
- Small Ubiquitin Related Modifier 3
- Small Ubiquitin Related Modifier Protein 1
- SMAP1
- SMAP2
- SMARCA1
- SMARCA2
- SMARCA4
- SMARCA5
- SMARCAD1
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