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SMARCA2 Produits

(SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 2 (SMARCA2))

Catégories

The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Two transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism. [provided by RefSeq, Jul 2008].

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Catégories SMARCA2 en vedette

SMARCA2 Anticorps

High quality antibodies with extensive validation data.

SMARCA2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SMARCA2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Chicken, Dog, Human, Mouse, Rat
Application WB, IHC, IP, IF
Validations
  • (3)
  • (4)
N° du produit ABIN967939
Quantité 150 μg
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC, ChIP
Validations
  • (3)
N° du produit ABIN7164521
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IF
Validations
  • (3)
N° du produit ABIN520280
Quantité 100 μg
Fiche technique Fiche technique

SMARCA2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1320621
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (2)
N° du produit ABIN2669725
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (2)
N° du produit ABIN2669697
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits SMARCA2

Jelinic, Schlappe, Conlon, Tseng, Olvera, Dao, Mueller, Hussein, Soslow, Levine: "Concomitant loss of SMARCA2 and SMARCA4 expression in small cell carcinoma of the ovary, hypercalcemic type." dans: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 29, Issue 1, pp. 60-6, (2015) (PubMed).

Van Houdt, Nowakowska, Sousa, van Schaik, Seuntjens, Avonce, Sifrim, Abdul-Rahman, van den Boogaard, Bottani, Castori, Cormier-Daire, Deardorff, Filges, Fryer, Fryns, Gana, Garavelli et al.: "Heterozygous missense mutations in SMARCA2 cause Nicolaides-Baraitser syndrome. ..." dans: Nature genetics, Vol. 44, Issue 4, pp. 445-9, S1, (2012) (PubMed).

Okada, Harada, Saiwai, Nakamura, Ohkawa: "Generation of a rat monoclonal antibody specific for Brm." dans: Hybridoma (2005), Vol. 28, Issue 6, pp. 455-8, (2009) (PubMed).

Yamamichi-Nishina, Ito, Mizutani, Yamamichi, Watanabe, Iba: "SW13 cells can transition between two distinct subtypes by switching expression of BRG1 and Brm genes at the post-transcriptional level." dans: The Journal of biological chemistry, Vol. 278, Issue 9, pp. 7422-30, (2003) (PubMed).

Iba, Mizutani, Ito: "SWI/SNF chromatin remodelling complex and retroviral gene silencing." dans: Reviews in medical virology, Vol. 13, Issue 2, pp. 99-110, (2003) (PubMed).

Klochendler-Yeivin, Muchardt, Yaniv: "SWI/SNF chromatin remodeling and cancer." dans: Current opinion in genetics & development, Vol. 12, Issue 1, pp. 73-9, (2002) (PubMed).

Mizutani, Ito, Nishina, Yamamichi, Watanabe, Iba: "Maintenance of integrated proviral gene expression requires Brm, a catalytic subunit of SWI/SNF complex." dans: The Journal of biological chemistry, Vol. 277, Issue 18, pp. 15859-64, (2002) (PubMed).

Wong, Shanahan, Chen, Lian, Ha, Hendricks, Ghaffari, Iliev, Penn, Woodland, Smith, Salada, Carillo, Laity, Gupte, Swedlund, Tavtigian, Teng, Lees: "BRG1, a component of the SWI-SNF complex, is mutated in multiple human tumor cell lines." dans: Cancer research, Vol. 60, Issue 21, pp. 6171-7, (2000) (PubMed).

Sudarsanam, Winston: "The Swi/Snf family nucleosome-remodeling complexes and transcriptional control." dans: Trends in genetics : TIG, Vol. 16, Issue 8, pp. 345-51, (2000) (PubMed).

Singh, Coe, Hong: "A role for retinoblastoma protein in potentiating transcriptional activation by the glucocorticoid receptor." dans: Nature, Vol. 374, Issue 6522, pp. 562-5, (1995) (PubMed).

Synonymes et noms alternatifs relatifs à SMARCA2

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (SMARCA2), SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 L homeolog (smarca2.L), SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (Smarca2), SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (smarca2), 2610209L14Rik, BAF190, brahma, Brahma, BRM, brm, hBRM, hSNF2a, NCBRS, psa-4, SNF2, SNF2alpha, SNF2L2, Snf2l2, SNF2LA, Sth1p, SWI2, wu:fa56c07, wu:fi27f11, zgc:66238

Protein level used designations for SMARCA2

  • ATP-dependent helicase SMARCA2
  • BAF190B
  • BRG1-associated factor 190B
  • SNF2-alpha
  • SNF2/SWI2-like protein 2
  • SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2
  • global transcription activator homologous sequence
  • probable global transcription activator SNF2L2
  • protein brahma homolog
  • sucrose nonfermenting 2-like protein 2
  • SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2
  • subunit of the SWI/SNF chromatin remodeling complex
  • phasmid Socket Absent PSA-4
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