SMARCA4 Produits
(SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4))
Catégories
The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012].
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Catégories SMARCA4 en vedette
SMARCA4 Anticorps
High quality antibodies with extensive validation data.
SMARCA4 Kits ELISA
Reliable ELISA kits for a wide range of species.
SMARCA4 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
SMARCA4 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, IHC (p), CUT&RUN
Validations
- (2)
- (1)
N° du produit
ABIN6991990
Quantité
0.1 mg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IF, IP
Validations
- (5)
N° du produit
ABIN3022959
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IF, IP
Validations
- (6)
N° du produit
ABIN2451926
Quantité
100 μg
Fiche technique
Fiche technique
SMARCA4 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6975082
Quantité
96 tests
Fiche technique
Fiche technique
SMARCA4 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1320623
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (2)
N° du produit
ABIN2669726
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN2131870
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits SMARCA4
: "Celastrol ameliorates liver metabolic damage caused by a high-fat diet through Sirt1." dans: Molecular metabolism, Vol. 6, Issue 1, pp. 138-147, (2018) (PubMed).: "Brg1 Enables Rapid Growth of the Early Embryo by Suppressing Genes That Regulate Apoptosis and Cell Growth Arrest." dans: Molecular and cellular biology, Vol. 36, Issue 15, pp. 1990-2010, (2016) (PubMed).
: "SNORD76, a box C/D snoRNA, acts as a tumor suppressor in glioblastoma." dans: Scientific reports, Vol. 5, pp. 8588, (2015) (PubMed).
: "Concomitant loss of SMARCA2 and SMARCA4 expression in small cell carcinoma of the ovary, hypercalcemic type." dans: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 29, Issue 1, pp. 60-6, (2015) (PubMed).
: "Analysis of the SWI/SNF chromatin-remodeling complex during early heart development and BAF250a repression cardiac gene transcription during P19 cell differentiation." dans: Nucleic acids research, Vol. 42, Issue 5, pp. 2958-75, (2014) (PubMed).
: "Nuclear actin polymerization is required for transcriptional reprogramming of Oct4 by oocytes." dans: Genes & development, Vol. 25, Issue 9, pp. 946-58, (2011) (PubMed).
: "Chromatin remodeling by imitation switch (ISWI) class ATP-dependent remodelers is stimulated by histone variant H2A.Z." dans: The Journal of biological chemistry, Vol. 285, Issue 7, pp. 4645-51, (2010) (PubMed).
: "Production of a rat monoclonal antibody against Brg1." dans: Hybridoma (2005), Vol. 28, Issue 6, pp. 463-6, (2009) (PubMed).
: "The microphthalmia-associated transcription factor requires SWI/SNF enzymes to activate melanocyte-specific genes." dans: The Journal of biological chemistry, Vol. 281, Issue 29, pp. 20233-41, (2006) (PubMed).
Synonymes et noms alternatifs relatifs à SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 (SMARCA4), SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 (Smarca4), b2b692Clo, BAF190, BAF190A, brg-1, BRG1, Brg1, HP1-BP72, hSNF2b, MRD16, RTPS2, SMARCA4, SNF2, SNF2beta, SNF2L4, SNF2LB, SW1/SNF, SWI2Protein level used designations for SMARCA4
- SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4
- transcription activator BRG1-like
- ATP-dependent helicase SMARCA4
- BRG1-associated factor 190A
- BRM/SWI2-related gene 1
- SNF2-beta
- SNF2-like 4
- brahma protein-like 1
- global transcription activator homologous sequence
- homeotic gene regulator
- mitotic growth and transcription activator
- nuclear protein GRB1
- protein BRG-1
- protein brahma homolog 1
- sucrose nonfermenting-like 4
- transcription activator BRG1
- BAF190A
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4
- SWI/SNF related transcriptional activator
- WI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
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