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SMC1A Produits

(Structural Maintenance of Chromosomes 1A (SMC1A))

Catégories

Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1L2 or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. [provided by RefSeq, Jul 2008].

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Catégories SMC1A en vedette

SMC1A Anticorps

High quality antibodies with extensive validation data.

SMC1A Kits ELISA

Reliable ELISA kits for a wide range of species.

SMC1A Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SMC1A recommandé Anticorps

Produit

Reactivity

Application

Validations

N° du produit

Quantité

Fiche technique

anti-SMC1A anticorps (pSer957)

Reactivity Human

Application WB, IHC, IP

Validations

N° du produit ABIN3019554

Quantité 100 μL

Fiche technique Fiche technique

anti-SMC1A anticorps

Reactivity Human

Application WB, IHC, ELISA, FACS, ICC

Validations

N° du produit ABIN969406

Quantité 100 μL

Fiche technique Fiche technique

anti-SMC1A anticorps (pSer957)

Reactivity Human, Mouse, Rat

Application WB, IF

Validations

N° du produit ABIN7265084

Quantité 200 μL

Fiche technique Fiche technique

SMC1A recommandé Kits ELISA

Produit

Reactivity

Analytical Method

Validations

N° du produit

Quantité

Fiche technique

SMC1A Kit ELISA

Reactivity Human, Mouse

Analytical Method Qualitative Cell ELISA

Validations

N° du produit ABIN1380699

Quantité 2 x 96 tests

Fiche technique Fiche technique

SMC1A Kit ELISA

Reactivity Human, Mouse, Rat

Analytical Method Qualitative Cell ELISA

Validations

N° du produit ABIN1380263

Quantité 2 x 96 tests

Fiche technique Fiche technique

SMC1A recommandé Protéines

Produit

Reactivity

Source

Validations

N° du produit

Quantité

Fiche technique

SMC1A Protein (AA 366-465) (GST tag)

Reactivity Human

Source Wheat germ

Validations

N° du produit ABIN1320652

Quantité 10 μg

Fiche technique Fiche technique

SMC1A Protein (AA 1-1233) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

N° du produit ABIN3095589

Quantité 1 mg

Fiche technique Fiche technique

SMC1A Protein (AA 1-1233) (Strep Tag)

Reactivity Mouse

Source Tobacco (Nicotiana tabacum)

Validations

N° du produit ABIN3137039

Quantité 1 mg

Fiche technique Fiche technique

Dernières publications sur nos produits SMC1A

Wang, Jette, Moussienko, Bebb, Lees-Miller: "ATM-Deficient Colorectal Cancer Cells Are Sensitive to the PARP Inhibitor Olaparib." dans: Translational oncology, Vol. 10, Issue 2, pp. 190-196, (2017) (PubMed).

Batenburg, Thompson, Hendrickson, Zhu: "Cockayne syndrome group B protein regulates DNA double-strand break repair and checkpoint activation." dans: The EMBO journal, Vol. 34, Issue 10, pp. 1399-416, (2015) (PubMed).

Valdez, Li, Murray, Ji, Liu, Popat, Champlin, Andersson: "Comparison of the cytotoxicity of cladribine and clofarabine when combined with fludarabine and busulfan in AML cells: Enhancement of cytotoxicity with epigenetic modulators." dans: Experimental hematology, Vol. 43, Issue 6, pp. 448-61.e2, (2015) (PubMed).

Houlihan, Feng: "The scaffold protein Nde1 safeguards the brain genome during S phase of early neural progenitor differentiation." dans: eLife, Vol. 3, pp. e03297, (2014) (PubMed).

Cucco, Servadio, Gatti, Bianchi, Mannini, Prodosmo, De Vitis, Basso, Friuli, Laghi, Soddu, Fontanini, Musio: "Mutant cohesin drives chromosomal instability in early colorectal adenomas." dans: Human molecular genetics, Vol. 23, Issue 25, pp. 6773-8, (2014) (PubMed).

Lee, Martin, Nakamura, Azghadi, Amiri, Ben-David, Perlman, Gatti, Hu, Lowry: "SMRT compounds abrogate cellular phenotypes of ataxia telangiectasia in neural derivatives of patient-specific hiPSCs." dans: Nature communications, Vol. 4, pp. 1824, (2013) (PubMed).

Puccini, Shalini, Voss, Gatei, Wilson, Hiwase, Lavin, Dorstyn, Kumar: "Loss of caspase-2 augments lymphomagenesis and enhances genomic instability in Atm-deficient mice." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 49, pp. 19920-5, (2013) (PubMed).

Williamson, Kubota, Hamill, Klimowicz, Ye, Muzik, Dean, Tu, Gilley, Magliocco, McKay, Bebb, Lees-Miller: "Enhanced cytotoxicity of PARP inhibition in mantle cell lymphoma harbouring mutations in both ATM and p53." dans: EMBO molecular medicine, Vol. 4, Issue 6, pp. 515-27, (2012) (PubMed).

Valdez, Nieto, Murray, Li, Wang, Champlin, Andersson: "Epigenetic modifiers enhance the synergistic cytotoxicity of combined nucleoside analog-DNA alkylating agents in lymphoma cell lines." dans: Experimental hematology, Vol. 40, Issue 10, pp. 800-10, (2012) (PubMed).

Daniel, Pellegrini, Lee, Guo, Filsuf, Belkina, You, Paull, Sleckman, Feigenbaum, Nussenzweig: "Loss of ATM kinase activity leads to embryonic lethality in mice." dans: The Journal of cell biology, Vol. 198, Issue 3, pp. 295-304, (2012) (PubMed).

Synonymes et noms alternatifs relatifs à SMC1A

structural maintenance of chromosomes 1A (SMC1A), structural maintenance of chromosomes 1A (smc1a), structural maintenance of chromosomes 1A (Smc1a), structural maintenance of chromosomes 1A b (smc1ab), structural maintenance of chromosomes 1A L homeolog (smc1a.L), 5830426I24Rik, CDLS2, DXS423E, mKIAA0178, NV15570, SB1.8, Sb1.8, SMC-1A, SMC1, Smc1, smc1, smc1a, smc1aa, SMC1alpha, Smc1alpha, SMC1L1, Smc1l1, smc1l1, SMCB, Smcb, xSMC1

Protein level used designations for SMC1A

SMC protein 1A
SMC-1-alpha
SMC1 (structural maintenance of chromosomes 1, yeast)-like 1
segregation of mitotic chromosomes 1
structural maintenance of chromosomes protein 1A
SMC-protein
SMC1 structural maintenance of chromosomes 1-like 1
structural maintenance of chromosomes 1A
structural maintenance of chromosomes protein 1A-like
SMC (segregation of mitotic chromosomes 1)-like 1
chromosome segregation protein SmcB
segregation of mitotic chromosomes b
SMC1 protein cohesin subunit
structural maintenance of chromosomes 1
DXhXs423e
SMC-like 1
segregation of mitotic chromosomes-like 1
structural maintenance of chromosomes 1 like 1
14S cohesin SMC1 subunit
structural maintenance of chromosomes 1A a
LOW QUALITY PROTEIN: structural maintenance of chromosomes protein 1A

Avez-vous cherché autre chose?

SMC1B
SMC2
SMC3
SMC4
SMC5
SMC6
SMCHD1
SMCO1
SMCO2
SMCO4
SMCP
SMCR5
SMCR7
SMCR7L
SMCR8
SMDA
SMEK Homolog 2, Suppressor of Mek1 (Dictyostelium)
SMEK1
SMG1
SMG1P5

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SMC1A Produits

(Structural Maintenance of Chromosomes 1A (SMC1A))

Catégories SMC1A en vedette

SMC1A Anticorps

SMC1A Kits ELISA

SMC1A Protéines

SMC1A recommandé Anticorps

SMC1A recommandé Kits ELISA

SMC1A recommandé Protéines

Dernières publications sur nos produits SMC1A

Synonymes et noms alternatifs relatifs à SMC1A

Protein level used designations for SMC1A

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