SMC1A Produits
(Structural Maintenance of Chromosomes 1A (SMC1A))
Catégories
Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1L2 or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. [provided by RefSeq, Jul 2008].
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Catégories SMC1A en vedette
SMC1A Anticorps
High quality antibodies with extensive validation data.
SMC1A Kits ELISA
Reliable ELISA kits for a wide range of species.
SMC1A Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
SMC1A recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP
Validations
- (7)
N° du produit
ABIN3019554
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, ELISA, FACS, ICC
Validations
- (1)
- (4)
N° du produit
ABIN969406
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IF
Validations
- (4)
N° du produit
ABIN7265084
Quantité
200 μL
Fiche technique
Fiche technique
SMC1A recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1380699
Quantité
2 x 96 tests
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1380263
Quantité
2 x 96 tests
Fiche technique
Fiche technique
SMC1A recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1320652
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3095589
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3137039
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits SMC1A
: "ATM-Deficient Colorectal Cancer Cells Are Sensitive to the PARP Inhibitor Olaparib." dans: Translational oncology, Vol. 10, Issue 2, pp. 190-196, (2017) (PubMed).: "Cockayne syndrome group B protein regulates DNA double-strand break repair and checkpoint activation." dans: The EMBO journal, Vol. 34, Issue 10, pp. 1399-416, (2015) (PubMed).
: "Comparison of the cytotoxicity of cladribine and clofarabine when combined with fludarabine and busulfan in AML cells: Enhancement of cytotoxicity with epigenetic modulators." dans: Experimental hematology, Vol. 43, Issue 6, pp. 448-61.e2, (2015) (PubMed).
: "The scaffold protein Nde1 safeguards the brain genome during S phase of early neural progenitor differentiation." dans: eLife, Vol. 3, pp. e03297, (2014) (PubMed).
: "Mutant cohesin drives chromosomal instability in early colorectal adenomas." dans: Human molecular genetics, Vol. 23, Issue 25, pp. 6773-8, (2014) (PubMed).
: "SMRT compounds abrogate cellular phenotypes of ataxia telangiectasia in neural derivatives of patient-specific hiPSCs." dans: Nature communications, Vol. 4, pp. 1824, (2013) (PubMed).
: "Loss of caspase-2 augments lymphomagenesis and enhances genomic instability in Atm-deficient mice." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 49, pp. 19920-5, (2013) (PubMed).
: "Enhanced cytotoxicity of PARP inhibition in mantle cell lymphoma harbouring mutations in both ATM and p53." dans: EMBO molecular medicine, Vol. 4, Issue 6, pp. 515-27, (2012) (PubMed).
: "Epigenetic modifiers enhance the synergistic cytotoxicity of combined nucleoside analog-DNA alkylating agents in lymphoma cell lines." dans: Experimental hematology, Vol. 40, Issue 10, pp. 800-10, (2012) (PubMed).
: "Loss of ATM kinase activity leads to embryonic lethality in mice." dans: The Journal of cell biology, Vol. 198, Issue 3, pp. 295-304, (2012) (PubMed).
Synonymes et noms alternatifs relatifs à SMC1A
structural maintenance of chromosomes 1A (SMC1A), structural maintenance of chromosomes 1A (smc1a), structural maintenance of chromosomes 1A (Smc1a), structural maintenance of chromosomes 1A b (smc1ab), structural maintenance of chromosomes 1A L homeolog (smc1a.L), 5830426I24Rik, CDLS2, DXS423E, mKIAA0178, NV15570, SB1.8, Sb1.8, SMC-1A, SMC1, Smc1, smc1, smc1a, smc1aa, SMC1alpha, Smc1alpha, SMC1L1, Smc1l1, smc1l1, SMCB, Smcb, xSMC1Protein level used designations for SMC1A
- SMC protein 1A
- SMC-1-alpha
- SMC1 (structural maintenance of chromosomes 1, yeast)-like 1
- segregation of mitotic chromosomes 1
- structural maintenance of chromosomes protein 1A
- SMC-protein
- SMC1 structural maintenance of chromosomes 1-like 1
- structural maintenance of chromosomes 1A
- structural maintenance of chromosomes protein 1A-like
- SMC (segregation of mitotic chromosomes 1)-like 1
- chromosome segregation protein SmcB
- segregation of mitotic chromosomes b
- SMC1 protein cohesin subunit
- structural maintenance of chromosomes 1
- DXhXs423e
- SMC-like 1
- segregation of mitotic chromosomes-like 1
- structural maintenance of chromosomes 1 like 1
- 14S cohesin SMC1 subunit
- structural maintenance of chromosomes 1A a
- LOW QUALITY PROTEIN: structural maintenance of chromosomes protein 1A
Avez-vous cherché autre chose?
- SMARCE1
- SMARCD3
- SMARCD2
- SMARCD1
- SMARCC2
- SMARCC1
- SMARCB1
- SMARCAL1
- SMARCAD1
- SMARCA5
- SMARCA4
- SMARCA2
- SMARCA1
- SMAP2
- SMAP1
- Small Ubiquitin Related Modifier Protein 1
- Small Ubiquitin Related Modifier 3
- Small Proline-Rich Protein 2B
- Small Nuclear RNA Activating Complex, Polypeptide 1, 43kDa
- Small Nuclear Ribonucleoprotein Polypeptide A
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