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SMC3 Produits

(Structural Maintenance of Chromosomes 3 (SMC3))

Catégories

This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein. [provided by RefSeq, Jul 2008].

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Catégories SMC3 en vedette

SMC3 Anticorps

High quality antibodies with extensive validation data.

SMC3 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SMC3 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
N° du produit ABIN7440092
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (3)
N° du produit ABIN522580
Quantité 50 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (3)
N° du produit ABIN522583
Quantité 100 μg
Fiche technique Fiche technique

SMC3 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6211766
Quantité 96 tests
Fiche technique Fiche technique

SMC3 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1320659
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7406332
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3095549
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits SMC3

Bowman, Balukof, Ford, Smolikove: "A Novel Role for α-Importins and Akirin in Establishment of Meiotic Sister Chromatid Cohesion in Caenorhabditis elegans." dans: Genetics, Vol. 211, Issue 2, pp. 617-635, (2019) (PubMed).

Deardorff, Bando, Nakato, Watrin, Itoh, Minamino, Saitoh, Komata, Katou, Clark, Cole, De Baere, Decroos, Di Donato, Ernst, Francey, Gyftodimou, Hirashima, Hullings, Ishikawa, Jaulin, Kaur, Kiyono et al.: "HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle. ..." dans: Nature, Vol. 489, Issue 7415, pp. 313-7, (2012) (PubMed).

Shiomi, Hayashi, Ishii, Shinmyozu, Nakayama, Sugasawa, Nishitani: "Two different replication factor C proteins, Ctf18 and RFC1, separately control PCNA-CRL4Cdt2-mediated Cdt1 proteolysis during S phase and following UV irradiation." dans: Molecular and cellular biology, Vol. 32, Issue 12, pp. 2279-88, (2012) (PubMed).

Leman, Noguchi, Lee, Noguchi: "Human Timeless and Tipin stabilize replication forks and facilitate sister-chromatid cohesion." dans: Journal of cell science, Vol. 123, Issue Pt 5, pp. 660-70, (2010) (PubMed).

Adelfalk, Janschek, Revenkova, Blei, Liebe, Göb, Alsheimer, Benavente, de Boer, Novak, Höög, Scherthan, Jessberger: "Cohesin SMC1beta protects telomeres in meiocytes." dans: The Journal of cell biology, Vol. 187, Issue 2, pp. 185-99, (2009) (PubMed).

Terret, Sherwood, Rahman, Qin, Jallepalli: "Cohesin acetylation speeds the replication fork." dans: Nature, Vol. 462, Issue 7270, pp. 231-4, (2009) (PubMed).

Rankin, Ayad, Kirschner: "Sororin, a substrate of the anaphase-promoting complex, is required for sister chromatid cohesion in vertebrates." dans: Molecular cell, Vol. 18, Issue 2, pp. 185-200, (2005) (PubMed).

Revenkova, Eijpe, Heyting, Hodges, Hunt, Liebe, Scherthan, Jessberger: "Cohesin SMC1 beta is required for meiotic chromosome dynamics, sister chromatid cohesion and DNA recombination." dans: Nature cell biology, Vol. 6, Issue 6, pp. 555-62, (2004) (PubMed).

Synonymes et noms alternatifs relatifs à SMC3

structural maintenance of chromosomes 3 (smc3), structural maintenance of chromosomes 3 (SMC3), structural maintenance of chromosomes 3 (Smc3), structural maintenance of chromosomes 3 S homeolog (smc3.S), BAM, Bamacan, bamacan, BMH, CDLS3, cspg6, CSPG6, Cspg6, HCAP, im:7142991, Mmip1, SMC-3, SMC3L1, SmcD, wu:fb22e01, wu:fc30d07, xsmc3

Protein level used designations for SMC3

  • chondroitin sulfate proteoglycan 6 (bamacan)
  • SMC protein 3
  • basement membrane-associated chondroitin proteoglycan
  • chromosome-associated polypeptide
  • structural maintenance of chromosomes protein 3
  • chondroitin sulfate proteoglycan 6
  • chromosome segregation protein SmcD
  • mad member-interacting protein 1
  • structural maintenace of chromosomes 3
  • cohesin complex subunit
  • bamacan
  • basement membrane chondroitin sulfate proteoglycan
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