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SNAP23 Produits

(Synaptosomal-Associated Protein, 23kDa (SNAP23))

Catégories

Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008].

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Catégories SNAP23 en vedette

SNAP23 Anticorps

High quality antibodies with extensive validation data.

SNAP23 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SNAP23 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
N° du produit ABIN7444214
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (7)
N° du produit ABIN7444226
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IP, IHC (p)
Validations
  • (5)
N° du produit ABIN563782
Quantité 100 μg
Fiche technique Fiche technique

SNAP23 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6221616
Quantité 96 tests
Fiche technique Fiche technique

SNAP23 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1320745
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN934997
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7505232
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits SNAP23

Tadokoro, Shibata, Inoh, Amano, Nakanishi, Hirashima, Utsunomiya-Tate: "Phosphorylation of syntaxin-3 at Thr 14 negatively regulates exocytosis in RBL-2H3 mast cells." dans: Cell biology international, Vol. 40, Issue 5, pp. 589-96, (2016) (PubMed).

Martineau, Shi, Puyal, Knolhoff, Dulong, Gasnier, Klingauf, Sweedler, Jahn, Mothet: "Storage and uptake of D-serine into astrocytic synaptic-like vesicles specify gliotransmission." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 8, pp. 3413-23, (2013) (PubMed).

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." dans: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Stadler, Hjelmare, Neumann, Jonasson, Pepperkok, Uhlén, Lundberg: "Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy." dans: Journal of proteomics, Vol. 75, Issue 7, pp. 2236-51, (2012) (PubMed).

Boström, Andersson, Vind, Håversen, Rutberg, Wickström, Larsson, Jansson, Svensson, Brånemark, Ling, Beck-Nielsen, Borén, Højlund, Olofsson: "The SNARE protein SNAP23 and the SNARE-interacting protein Munc18c in human skeletal muscle are implicated in insulin resistance/type 2 diabetes." dans: Diabetes, Vol. 59, Issue 8, pp. 1870-8, (2010) (PubMed).

Gratacòs, Costas, de Cid, Bayés, González, Baca-García, de Diego, Fernández-Aranda, Fernández-Piqueras, Guitart, Martín-Santos, Martorell, Menchón, Roca, Sáiz-Ruiz, Sanjuán, Torrens, Urretavizcaya et al.: "Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and ..." dans: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 150B, Issue 6, pp. 808-16, (2009) (PubMed).

Synonymes et noms alternatifs relatifs à SNAP23

synaptosome associated protein 23 (SNAP23), synaptosome associated protein 23kDa (snap23), synaptosomal-associated protein 23 (Snap23), synaptosome associated protein 23 (Snap23), synaptosome associated protein 23kDa L homeolog (snap23.L), 23kDa, AA408749, HsT17016, SNAP-23, snap23-A, SNAP23A, SNAP23B, Sndt, Syndet, XOSNAP-23

Protein level used designations for SNAP23

  • synaptosomal-associated protein 23
  • synaptosomal-associated protein 23 isoform SNAP23A
  • synaptosomal-associated protein, 23kDa
  • synaptosomal-associated protein, 23kD
  • vesicle-membrane fusion protein SNAP-23
  • SNAP-23
  • synaptosomal-associated protein 23 kD
  • synaptosomal-associated protein, 23 kD
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