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SNAPIN Produits

(SNAP-Associated Protein (SNAPIN))

Catégories

The protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) complex of proteins and the BLOC-1 (biogenesis of lysosome-related organelles) complex. Biochemical studies have identified additional binding partners. As part of the SNARE complex, it is required for vesicle docking and fusion and regulates neurotransmitter release. The BLOC-1 complex is required for the biogenesis of specialized organelles such as melanosomes and platelet dense granules. Mutations in gene products that form the BLOC-1 complex have been identified in mouse strains that are models of Hermansky-Pudlak syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012].

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Catégories SNAPIN en vedette

SNAPIN Anticorps

High quality antibodies with extensive validation data.

SNAPIN Kits ELISA

Reliable ELISA kits for a wide range of species.

SNAPIN Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SNAPIN recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (3)
N° du produit ABIN525253
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC
Validations
  • (3)
N° du produit ABIN6148187
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (2)
N° du produit ABIN7441457
Quantité 100 μL
Fiche technique Fiche technique

SNAPIN recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6959541
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1158381
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method
Validations
N° du produit ABIN1158382
Quantité 96 tests
Fiche technique Fiche technique

SNAPIN recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN666875
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1320772
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1320770
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits SNAPIN

Makani, Sultana, Sie, Orjiako, Tatangelo, Dowling, Cai, Pierce, Allan Butterfield, Hill, Park: "Annexin A1 complex mediates oxytocin vesicle transport." dans: Journal of neuroendocrinology, Vol. 25, Issue 12, pp. 1241-54, (2014) (PubMed).

Yun, Park, Ho, Kim, Kim, Oh, Ga, Seo, Chang, Son, Seol: "LRRK2 phosphorylates Snapin and inhibits interaction of Snapin with SNAP-25." dans: Experimental & molecular medicine, Vol. 45, pp. e36, (2013) (PubMed).

Zhou, Cai, Xie, Sheng: "Snapin recruits dynein to BDNF-TrkB signaling endosomes for retrograde axonal transport and is essential for dendrite growth of cortical neurons." dans: Cell reports, Vol. 2, Issue 1, pp. 42-51, (2012) (PubMed).

Zhang, Wada, Yasuhara, Iseda, Eguchi, Fukui, Yang, Yamagata, Hiesberger, Igarashi, Zhang, Wang, Akagi, Kanwar, Makino: "The role for HNF-1beta-targeted collectrin in maintenance of primary cilia and cell polarity in collecting duct cells." dans: PLoS ONE, Vol. 2, Issue 5, pp. e414, (2007) (PubMed).

Takamori, Holt, Stenius, Lemke, Grønborg, Riedel, Urlaub, Schenck, Brügger, Ringler, Müller, Rammner, Gräter, Hub, De Groot, Mieskes, Moriyama, Klingauf, Grubmüller, Heuser, Wieland, Jahn: "Molecular anatomy of a trafficking organelle." dans: Cell, Vol. 127, Issue 4, pp. 831-46, (2006) (PubMed).

Vites, Rhee, Schwarz, Rosenmund, Jahn: "Reinvestigation of the role of snapin in neurotransmitter release." dans: The Journal of biological chemistry, Vol. 279, Issue 25, pp. 26251-6, (2004) (PubMed).

Synonymes et noms alternatifs relatifs à SNAPIN

SNAP associated protein (SNAPIN), SNAP-associated protein L homeolog (snapin.L), SNAP-associated protein (snapin), SNAP-associated protein (Snapin), 25kDa, AA407989, AV026596, BLOC1S7, Bloc1s7, BLOS7, si:dkey-222b8.2, Snap25bp, SNAPAP, Snapap, SNAPIN

Protein level used designations for SNAPIN

  • SNAP-associated protein
  • SNARE-associated protein Snapin
  • BLOC-1 subunit 7
  • SNAP-25-binding protein
  • SNARE associated protein snapin
  • biogenesis of lysosomal organelles complex-1, subunit 7
  • biogenesis of lysosome-related organelles complex 1 subunit 7
  • synaptosomal-associated protein 25-binding protein
  • synaptosomal-associated protein 25 binding protein
  • synaptosomal-associated protein, 25 kDa, binding protein
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