SOCS3 Produits
(Suppressor of Cytokine Signaling 3 (SOCS3))
Catégories
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. [provided by RefSeq, Jul 2008].
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Catégories SOCS3 en vedette
SOCS3 Anticorps
High quality antibodies with extensive validation data.
SOCS3 Kits ELISA
Reliable ELISA kits for a wide range of species.
SOCS3 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
SOCS3 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (1)
- (7)
N° du produit
ABIN3021100
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IF, IHC (p)
Validations
- (1)
- (3)
N° du produit
ABIN522456
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse, Rat
Application
ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (4)
- (2)
N° du produit
ABIN670416
Quantité
100 μL
Fiche technique
Fiche technique
SOCS3 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (5)
- (1)
N° du produit
ABIN6959767
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6959768
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6970484
Quantité
96 tests
Fiche technique
Fiche technique
SOCS3 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
N° du produit
ABIN1320930
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7125255
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7400231
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits SOCS3
: "Resident alveolar macrophage-derived vesicular SOCS3 dampens allergic airway inflammation." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 34, Issue 3, pp. 4718-4731, (2021) (PubMed).: "Alveolar macrophage secretion of vesicular SOCS3 represents a platform for lung cancer therapeutics." dans: JCI insight, Vol. 4, Issue 20, (2020) (PubMed).
: "Olmesartan attenuates type 2 diabetes-associated liver injury: Cross-talk of AGE/RAGE/JNK, STAT3/SCOS3 and RAS signaling pathways." dans: European journal of pharmacology, Vol. 874, pp. 173010, (2020) (PubMed).
: "SOCS3-deficient lung epithelial cells uptaking neutrophil-derived SOCS3 worsens lung influenza infection." dans: Molecular immunology, Vol. 125, pp. 51-62, (2020) (PubMed).
: "The FXR Agonist, Obeticholic Acid, Suppresses HCC Proliferation & Metastasis: Role of IL-6/STAT3 Signalling Pathway." dans: Scientific reports, Vol. 7, Issue 1, pp. 12502, (2019) (PubMed).
: "Endogenous peroxidases in sputum interfere with horse-radish peroxidase-based ELISAs." dans: Journal of immunological methods, Vol. 454, pp. 76-79, (2018) (PubMed).
: "Role of the JAK2/STAT3 signaling pathway in the pathogenesis of type 2 diabetes mellitus with macrovascular complications." dans: Oncotarget, Vol. 8, Issue 57, pp. 96958-96969, (2017) (PubMed).
: "MicroRNA-30c-5p ameliorates hypoxia-reoxygenation-induced tubular epithelial cell injury via HIF1α stabilization by targeting SOCS3." dans: Oncotarget, Vol. 8, Issue 54, pp. 92801-92814, (2017) (PubMed).
: "Alveolar Epithelial Cell-Derived Prostaglandin E2 Serves as a Request Signal for Macrophage Secretion of Suppressor of Cytokine Signaling 3 during Innate Inflammation." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 196, Issue 12, pp. 5112-20, (2016) (PubMed).
: "SOCS3 blocks HIF-1? expression to inhibit proliferation and angiogenesis of human small cell lung cancer by downregulating activation of Akt, but not STAT3." dans: Molecular medicine reports, Vol. 12, Issue 1, pp. 83-92, (2015) (PubMed).
Synonymes et noms alternatifs relatifs à SOCS3
suppressor of cytokine signaling 3a (socs3a), suppressor of cytokine signaling 3 S homeolog (socs3.S), suppressor of cytokine signaling 3 (socs3), suppressor of cytokine signaling 3 L homeolog (socs3.L), suppressor of cytokine signaling 3 (SOCS3), suppressor of cytokine signaling 3a (socs3), suppressor of cytokine signaling 3 (Socs3), atod4, ATOD4, cis3, CIS3, Cis3, cish3, Cish3, EF-10, Ef10, fj09e12, MGC64393, MGC75749, MGC81248, socs-3, SOCS-3, Socs-3, socs3, SOCS3, ssi-3, SSI-3, Ssi-3, ssi3, SSI3, Ssi3, wu:fj09e12, xsocs3, zgc:56537Protein level used designations for SOCS3
- suppressor of cytokine signaling 3
- suppressor of cytokine signaling 3a
- STAT-induced STAT inhibitor 3
- cytokine-inducible SH2 protein 3
- cytokine signaling suppressor
- SOCS-3
- CIS-3
- E2a-Pbx1 target gene in fibroblasts 10
- cytokine inducible SH2-containing protein 3
- suppressors of cytokine signaling 3
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