Sortilin 1 Produits
(Sortilin 1 (SORT1))
Catégories
This gene encodes a protein that is a multi-ligand type-1 receptor with similarity to the yeast carboxypeptidase Y sorting receptor Vps10 protein. The encoded protein, a trans-Golgi network (TGN) transmembrane protein, binds a number of unrelated ligands that participate in a wide range of cellular processes\; however, it lacks the typical features of a signalling receptor. In the TGN, furin mediates the activation of the mature binding form. The encoded protein consists of a large luminal domain, a single transmembrane segment and short C-terminal cytoplasmic tail. The luminal domain contains a cysteine-rich region similar to two corresponding segments in the yeast Vps10p\; the cytoplasmic tail is similar to the corresponding segment of the cation-independent mannose 6-phosphate receptor and the tail also interacts with the VHS domains of GGA (Golgi-associated, gamma-adaptin homologous, ARF-interacting) proteins. [provided by RefSeq, Jul 2008].
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Catégories Sortilin 1 en vedette
Sortilin 1 Anticorps
High quality antibodies with extensive validation data.
Sortilin 1 Kits ELISA
Reliable ELISA kits for a wide range of species.
Sortilin 1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Sortilin 1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
ELISA, WB
Validations
- (5)
N° du produit
ABIN562759
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB
Validations
- (3)
N° du produit
ABIN6148281
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
N° du produit
ABIN7170335
Quantité
100 μg
Fiche technique
Fiche technique
Sortilin 1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6970373
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6959642
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6975876
Quantité
96 tests
Fiche technique
Fiche technique
Sortilin 1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7125176
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7125175
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1320971
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Sortilin 1
: "proBDNF is modified by advanced glycation end products in Alzheimer's disease and causes neuronal apoptosis by inducing p75 neurotrophin receptor processing." dans: Molecular brain, Vol. 11, Issue 1, pp. 68, (2019) (PubMed).: "Circulating sortilin level as a potential biomarker for coronary atherosclerosis and diabetes mellitus." dans: Cardiovascular diabetology, Vol. 16, Issue 1, pp. 92, (2018) (PubMed).
: "Lack of human-like extracellular sortilin neuropathology in transgenic Alzheimer's disease model mice and macaques." dans: Alzheimer's research & therapy, Vol. 10, Issue 1, pp. 40, (2018) (PubMed).
: "Transcriptional control of intestinal cholesterol absorption, adipose energy expenditure and lipid handling by Sortilin." dans: Scientific reports, Vol. 8, Issue 1, pp. 9006, (2018) (PubMed).
: "Using intracellular markers to identify a novel set of surface markers for live cell purification from a heterogeneous hIPSC culture." dans: Scientific reports, Vol. 8, Issue 1, pp. 804, (2018) (PubMed).
: "Sortilin regulates sorting and secretion of Sonic hedgehog." dans: Journal of cell science, Vol. 129, Issue 20, pp. 3832-3844, (2016) (PubMed).
: "SORT1 Mutation Resulting in Sortilin Deficiency and p75(NTR) Upregulation in a Family With Essential Tremor." dans: ASN neuro, Vol. 7, Issue 4, (2015) (PubMed).
: "Production and Characterization of a Novel Monoclonal Antibody Against Human Sortilin." dans: Monoclonal antibodies in immunodiagnosis and immunotherapy, Vol. 34, Issue 6, pp. 390-5, (2015) (PubMed).
: "Amyloid Precursor-like Protein 2 and Sortilin Do Not Regulate the PCSK9 Convertase-mediated Low Density Lipoprotein Receptor Degradation but Interact with Each Other." dans: The Journal of biological chemistry, Vol. 290, Issue 30, pp. 18609-20, (2015) (PubMed).
: "Targeted manipulation of the sortilin-progranulin axis rescues progranulin haploinsufficiency." dans: Human molecular genetics, Vol. 23, Issue 6, pp. 1467-78, (2014) (PubMed).
Synonymes et noms alternatifs relatifs à Sortilin 1
sortilin 1 (SORT1), sortilin (TP01_0016), sortilin (BBOV_I002730), sortilin 1 S homeolog (sort1.S), sortilin 1 (Sort1), sortilin 1a (sort1a), 19.m02079, 2900053A11Rik, AI852375, gp95, Gp95, ldlcq6, LDLCQ6, NT3, Nt3, Ntr3, Nts3, Ntsr3, SORT1, sort1, sortilin, zgc:85953Protein level used designations for Sortilin 1
- sortilin 1
- sortilin
- sortilin-like
- 100 kDa NT receptor
- NTR3
- glycoprotein 95
- neurotensin receptor 3
- mNTR3
- glycoprotein 110
- gp110
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