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SOX2 Produits

(SRY (Sex Determining Region Y)-Box 2 (SOX2))
This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq, Jul 2008].

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Catégories SOX2 en vedette

SOX2 Anticorps

High quality antibodies with extensive validation data.

SOX2 Kits ELISA

Reliable ELISA kits for a wide range of species.

SOX2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SOX2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IF, FACS, ICC, IHC (p), IP, IHC (fro), CUT&RUN
Validations
  • (11)
  • (15)
  • (1)
N° du produit ABIN2855074
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Goat, Human, Mouse, Rat
Application WB, ELISA, FACS, ICC, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (8)
  • (6)
N° du produit ABIN669621
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IF, IP
Validations
  • (2)
  • (8)
N° du produit ABIN3021003
Quantité 100 μL
Fiche technique Fiche technique

SOX2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6970417
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6959701
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Semi-Quantitative DNA-Binding ELISA
Validations
  • (2)
N° du produit ABIN5526732
Quantité 96 tests
Fiche technique Fiche technique

SOX2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7125201
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7125200
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN666968
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits SOX2

Lenz, Konecna, Tichy, Machacova, Fiala, Hurnik, Kyllar: "Unique expression patterns of the embryonal stem cell marker SOX2 and hormone receptors suggest the existence of a subpopulation of epithelial stem/progenitor cells in porcine and bovine endometrium." dans: Veterinary medicine and science, (2022) (PubMed).

Pagin, Pernebrink, Giubbolini, Barone, Sambruni, Zhu, Chiara, Ottolenghi, Pavesi, Wei, Cantù, Nicolis: "Sox2 controls neural stem cell self-renewal through a Fos-centered gene regulatory network." dans: Stem cells (Dayton, Ohio), (2021) (PubMed).

Pagin, Pernebrink, Pitasi, Malighetti, Ngan, Ottolenghi, Pavesi, Cantù, Nicolis: "FOS Rescues Neuronal Differentiation of Sox2-Deleted Neural Stem Cells by Genome-Wide Regulation of Common SOX2 and AP1(FOS-JUN) Target Genes." dans: Cells, Vol. 10, Issue 7, (2021) (PubMed).

Chiu, Wu, Kuo, Miao, Zheng, Chen, Lin, Chang, Wang, Chou: "Critical role of SOX2-IGF2 signaling in aggressiveness of bladder cancer." dans: Scientific reports, Vol. 10, Issue 1, pp. 8261, (2020) (PubMed).

Li, Sun, Zhao, An, Zhang, Gu, Zhao, Wang, Liu: "Function of BMP4 in the Formation of Vasculogenic Mimicry in Hepatocellular Carcinoma." dans: Journal of Cancer, Vol. 11, Issue 9, pp. 2560-2571, (2020) (PubMed).

Zhao, Cai, Liu, Su, An, Moon, Lyu, Si, Chen, Lu: "lncRNA 5430416N02Rik Promotes the Proliferation of Mouse Embryonic Stem Cells by Activating Mid1 Expression through 3D Chromatin Architecture." dans: Stem cell reports, Vol. 14, Issue 3, pp. 493-505, (2020) (PubMed).

Hsu, Liu, Lin, Hsu, Hsu, Li, Hung: "Involvement of collagen XVII in pluripotency gene expression and metabolic reprogramming of lung cancer stem cells." dans: Journal of biomedical science, Vol. 27, Issue 1, pp. 5, (2020) (PubMed).

Klein, Günther, Kwok, Edenhofer, Üçeyler et al.: "Generation of the human induced pluripotent stem cell line (UKWNLi001-A) from skin fibroblasts of a woman with Fabry disease carrying the X-chromosomal heterozygous c.708 G > C (W236C) missense ..." dans: Stem cell research, Vol. 31, pp. 222-226, (2019) (PubMed).

Li, Baskfield, Lin, Beers, Zou, Liu, Jaffré, Roberts, Ottinger, Kontaridis, Zheng: "Generation of an induced pluripotent stem cell line (TRNDi003-A) from a Noonan syndrome with multiple lentigines (NSML) patient carrying a p.Q510P mutation in the PTPN11 gene." dans: Stem cell research, Vol. 34, pp. 101374, (2019) (PubMed).

Li, Pradhan, Xu, Baskfield, Farkhondeh, Cheng, Beers, Zou, Liu, Might, Rodems, Zheng: "Generation of an induced pluripotent stem cell line (TRNDi002-B) from a patient carrying compound heterozygous p.Q208X and p.G310G mutations in the NGLY1 gene." dans: Stem cell research, Vol. 34, pp. 101362, (2019) (PubMed).

Synonymes et noms alternatifs relatifs à SOX2

SRY-box 2 (SOX2), SRY box 2 (Sox2), SRY (sex determining region Y)-box 2 (Sox2), SRY (sex determining region Y)-box 2 (sox2), SRY-box 2 S homeolog (sox2.S), SRY-box 2 (Sox2), ANOP3, anop3, cb236, lcc, MCOPS3, mcops3, RGD1565646, Sox-2, sox-2, SRY-box2, wu:fb83g04, wu:fc14d07, Xsox-2, ysb, zgc:65860, zgc:77389

Protein level used designations for SOX2

  • SRY-related HMG-box gene 2
  • transcription factor SOX-2
  • transcription factor SOX2
  • SRY-box containing gene 2
  • SRY-box 2
  • SRY-related HMG-box 2
  • sex determining region Y-box 2
  • SRY (sex determining region Y)-box 2
  • soxp
  • transcription factor Sox-2
  • XSox2
  • XlSOX-2
  • sex-determining region Y-box 2
  • Sox2 transcription factor
  • cSox2
  • delta EF2a
  • LOW QUALITY PROTEIN: transcription factor SOX-2
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