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SOX4 Produits

(SRY (Sex Determining Region Y)-Box 4 (SOX4))

Catégories

This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. [provided by RefSeq, Jul 2008].

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Catégories SOX4 en vedette

SOX4 Anticorps

High quality antibodies with extensive validation data.

SOX4 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SOX4 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro)
Validations
  • (5)
N° du produit ABIN1387237
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p), IF, FACS
Validations
  • (1)
  • (4)
N° du produit ABIN388786
Quantité 400 μL
Fiche technique Fiche technique

Application WB, IHC
Validations
  • (13)
N° du produit ABIN2780469
Quantité 100 μL
Fiche technique Fiche technique

SOX4 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1321002
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (1)
N° du produit ABIN2732454
Quantité 20 μg
Fiche technique Fiche technique

Dernières publications sur nos produits SOX4

Liu, Wu, Zhou, Cai, Li, Hu, Gao, Feng, Wang, Peng, Qi, Liu, Han: "The SOX4/miR-17-92/RB1 Axis Promotes Prostate Cancer Progression." dans: Neoplasia (New York, N.Y.), Vol. 21, Issue 8, pp. 765-776, (2019) (PubMed).

Zhou, Wang, Huang, Chen, Zhao, Yao, Jin, Huang, Liu, Li: "Down-regulated SOX4 expression suppresses cell proliferation, metastasis and induces apoptosis in Xuanwei female lung cancer patients." dans: Journal of cellular biochemistry, Vol. 116, Issue 6, pp. 1007-18, (2015) (PubMed).

Koumangoye, Andl, Taubenslag, Zilberman, Taylor, Loomans, Andl: "SOX4 interacts with EZH2 and HDAC3 to suppress microRNA-31 in invasive esophageal cancer cells." dans: Molecular cancer, Vol. 14, pp. 24, (2015) (PubMed).

Kato, Bhattaram, Penzo-Méndez, Gadi, Lefebvre: "SOXC Transcription Factors Induce Cartilage Growth Plate Formation in Mouse Embryos by Promoting Noncanonical WNT Signaling." dans: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 30, Issue 9, pp. 1560-71, (2015) (PubMed).

Chen, Ruan, Wang, Han, Wang, Lou, Ruan, Qiu, Yang, Zhang: "miR-129-3p, as a diagnostic and prognostic biomarker for renal cell carcinoma, attenuates cell migration and invasion via downregulating multiple metastasis-related genes." dans: Journal of cancer research and clinical oncology, Vol. 140, Issue 8, pp. 1295-304, (2014) (PubMed).

Grau, Luque-Garcia, González-Peramato, Theodorescu, Palou, Fernandez-Gomez, Sánchez-Carbayo: "A quantitative proteomic analysis uncovers the relevance of CUL3 in bladder cancer aggressiveness." dans: PLoS ONE, Vol. 8, Issue 1, pp. e53328, (2013) (PubMed).

Usui, Mochizuki, Iida, Miyauchi, Satoh, Sock, Nakauchi, Aburatani, Murakami, Wegner, Watanabe: "The early retinal progenitor-expressed gene Sox11 regulates the timing of the differentiation of retinal cells." dans: Development (Cambridge, England), Vol. 140, Issue 4, pp. 740-50, (2013) (PubMed).

Medina, Castillo, Blanco, Sanz-Garcia, Largo, Alvarez, Yokota, Gonzalez-Neira, Benitez, Clevers, Cigudosa, Lazo, Sanchez-Cespedes: "The SRY-HMG box gene, SOX4, is a target of gene amplification at chromosome 6p in lung cancer." dans: Human molecular genetics, Vol. 18, Issue 7, pp. 1343-52, (2009) (PubMed).

Ruebel, Leontovich, Tanizaki, Jin, Stilling, Zhang, Coonse, Scheithauer, Lombardero, Kovacs, Lloyd: "Effects of TGFbeta1 on gene expression in the HP75 human pituitary tumor cell line identified by gene expression profiling." dans: Endocrine, Vol. 33, Issue 1, pp. 62-76, (2008) (PubMed).

Synonymes et noms alternatifs relatifs à SOX4

SRY-box 4 (SOX4), SRY box 4 (Sox4), SRY (sex determining region Y)-box 4 (Sox4), SRY (sex determining region Y)-box 4a (sox4a), AA682046, EVI16, Sox-4, sox4, wu:fb82f08, wu:fq41g10, zgc:65850, zgc:77392

Protein level used designations for SOX4

  • SRY-box containing protein 4
  • transcription factor SOX-4
  • SRY-related HMG-box gene 4
  • ecotropic viral integration site 16
  • SRY-box containing gene 4
  • SRY (sex determining region Y)-box 4
  • SRY (sex determining region Y)-box 4a
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