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SP1 Produits

(Sp1 Transcription Factor (SP1))
The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].

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Catégories SP1 en vedette

SP1 Anticorps

High quality antibodies with extensive validation data.

SP1 Kits ELISA

Reliable ELISA kits for a wide range of species.

SP1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SP1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IF, IHC (p), FACS
Validations
  • (1)
  • (5)
N° du produit ABIN655398
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (7)
N° du produit ABIN520394
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (6)
N° du produit ABIN520396
Quantité 100 μg
Fiche technique Fiche technique

SP1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6970380
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6970379
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6959647
Quantité 96 tests
Fiche technique Fiche technique

SP1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7125180
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1321017
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7386242
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits SP1

Zhang, Liu, Su, Bai, Zhao, Zhao: "Resistin impairs activation of protein C by suppressing EPCR and increasing SP1 expression." dans: Biomedicine & pharmacotherapy, Vol. 109, pp. 930-937, (2019) (PubMed).

Yang, Li, Wang, Hou, Qiu, Wang, Wu: "Long-term persistent infection of HPV 16 E6 up-regulate SP1 and hTERT by inhibiting LKB1 in lung cancer cells." dans: PLoS ONE, Vol. 12, Issue 8, pp. e0182775, (2017) (PubMed).

Zhang, Liu, Liu, Zhou, Song, Cao, An: "miR-182 aids in receptive endometrium development in dairy goats by down-regulating PTN expression." dans: PLoS ONE, Vol. 12, Issue 7, pp. e0179783, (2017) (PubMed).

Yang, Cui, Xue, Overstreet, Zhan, Shan, Li, Li, Wang, Zhang, Yu, Xu: "Resveratrol Represses Pokemon Expression in Human Glioma Cells." dans: Molecular neurobiology, Vol. 53, Issue 2, pp. 1266-78, (2016) (PubMed).

Lee, Park, Byun, Kim, Ryu, Lee, Kim: "Silencing of voltage-gated potassium channel KV9.3 inhibits proliferation in human colon and lung carcinoma cells." dans: Oncotarget, Vol. 6, Issue 10, pp. 8132-43, (2015) (PubMed).

Chen, Tang, Wu, Zheng, Yang, Hann: "Inactivation of PI3-K/Akt and reduction of SP1 and p65 expression increase the effect of solamargine on suppressing EP4 expression in human lung cancer cells." dans: Journal of experimental & clinical cancer research : CR, Vol. 34, pp. 154, (2015) (PubMed).

Sakamoto, Akiyama, Shimada, Zhu, Yuasa, Tanaka: "DNA Methylation in the Exon 1 Region and Complex Regulation of Twist1 Expression in Gastric Cancer Cells." dans: PLoS ONE, Vol. 10, Issue 12, pp. e0145630, (2015) (PubMed).

Lee, Ryu, Lee: "Serum starvation-induced voltage-gated potassium channel Kv7.5 expression and its regulation by Sp1 in canine osteosarcoma cells." dans: International journal of molecular sciences, Vol. 15, Issue 1, pp. 977-93, (2014) (PubMed).

Qi, Zhang, Li, Frank, Dai, Liu, Chen: "MicroRNA-29b regulates ethanol-induced neuronal apoptosis in the developing cerebellum through SP1/RAX/PKR cascade." dans: The Journal of biological chemistry, Vol. 289, Issue 14, pp. 10201-10, (2014) (PubMed).

Zhang, Wang, Qin, Liu, Sun, Liu, Kuang, Jiang, Zhang: "cis-Acting elements and trans-acting factors in the transcriptional regulation of raf kinase inhibitory protein expression." dans: PLoS ONE, Vol. 8, Issue 12, pp. e83097, (2014) (PubMed).

Synonymes et noms alternatifs relatifs à SP1

sp1 transcription factor (sp1), Sp1 transcription factor (sp1), Sp1 transcription factor (SP1), Sp1 transcription factor (Sp1), Sp1 transcription factor L homeolog (sp1.L), trans-acting transcription factor 1 (Sp1), 1110003E12Rik, AA450830, AI845540, fc18h09, SP1, Sp1-1, wu:fc18h09, zgc:85950

Protein level used designations for SP1

  • Sp1-like protein
  • transcription factor Sp1
  • transcription factor
  • Sp1 transcription factor
  • transcription factor Sp1-like
  • specificity protein 1
  • specific protein-1
  • trans-acting transcription factor 1
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