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SP100 Produits

(SP100 Nuclear Antigen (SP100))

Catégories

This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene\; one of which encodes a high-mobility group protein. [provided by RefSeq, Aug 2011].

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Catégories SP100 en vedette

SP100 Anticorps

High quality antibodies with extensive validation data.

SP100 Kits ELISA

Reliable ELISA kits for a wide range of species.

SP100 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SP100 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
N° du produit ABIN7442741
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, RNAi
Validations
  • (1)
  • (4)
N° du produit ABIN562971
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
  • (3)
N° du produit ABIN948494
Quantité 50 μg
Fiche technique Fiche technique

SP100 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN511609
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rabbit
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN775695
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Guinea Pig
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN777660
Quantité 96 tests
Fiche technique Fiche technique

SP100 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1321019
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1321021
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN2131910
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits SP100

Niu, Livingston, Li, Beran, Daffis, Ramakrishnan, Burdette, Peiser, Salas, Ramos, Yu, Cheng, Strubin, Delaney Iv, Fletcher: "The Smc5/6 Complex Restricts HBV when Localized to ND10 without Inducing an Innate Immune Response and Is Counteracted by the HBV X Protein Shortly after Infection." dans: PLoS ONE, Vol. 12, Issue 1, pp. e0169648, (2017) (PubMed).

Berard, Coombs, Severini: "Quantification of the host response proteome after herpes simplex virus type 1 infection." dans: Journal of proteome research, Vol. 14, Issue 5, pp. 2121-42, (2015) (PubMed).

Wagenknecht, Reuter, Scherer, Reichel, Müller, Stamminger: "Contribution of the Major ND10 Proteins PML, hDaxx and Sp100 to the Regulation of Human Cytomegalovirus Latency and Lytic Replication in the Monocytic Cell Line THP-1." dans: Viruses, Vol. 7, Issue 6, pp. 2884-907, (2015) (PubMed).

Full, Jungnickl, Reuter, Bogner, Brulois, Scholz, Stürzl, Myoung, Jung, Stamminger, Ensser: "Kaposi's sarcoma associated herpesvirus tegument protein ORF75 is essential for viral lytic replication and plays a critical role in the antagonization of ND10-instituted intrinsic immunity." dans: PLoS pathogens, Vol. 10, Issue 1, pp. e1003863, (2014) (PubMed).

Stepp, Meyers, McBride: "Sp100 provides intrinsic immunity against human papillomavirus infection." dans: mBio, Vol. 4, Issue 6, pp. e00845-13, (2013) (PubMed).

Adler, Tavalai, Müller, Stamminger: "Human cytomegalovirus immediate-early gene expression is restricted by the nuclear domain 10 component Sp100." dans: The Journal of general virology, Vol. 92, Issue Pt 7, pp. 1532-8, (2011) (PubMed).

Tavalai, Adler, Scherer, Riedl, Stamminger: "Evidence for a dual antiviral role of the major nuclear domain 10 component Sp100 during the immediate-early and late phases of the human cytomegalovirus replication cycle." dans: Journal of virology, Vol. 85, Issue 18, pp. 9447-58, (2011) (PubMed).

Synonymes et noms alternatifs relatifs à SP100

SP100 nuclear antigen (SP100), nuclear antigen Sp100 (Sp100), SP100 nuclear antigen (Sp100), nuclear autoantigen Sp-100 (LOC101120993), A430075G10Rik, lysp100b, SP100, SP140

Protein level used designations for SP100

  • SP100 nuclear antigen
  • nuclear autoantigen Sp-100
  • nuclear autoantigen Sp-100-like
  • nuclear dot-associated Sp100 protein
  • speckled 100 kDa
  • SP100-HMG nuclear autoantigen
  • nuclear antigen Sp100
  • Nuclear autoantigen Sp-100
  • SP140 nuclear body protein
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