SPANXB1 Produits
(SPANX Family, Member B1 (SPANXB1))
Catégories
Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene maps to chromosome X in a head-to-tail orientation with SPANX family member B2, which appears to be a duplication of the B1 locus. The SPANXB genes are unique members of this gene family, since they contain an additional 18 nt in their coding region compared to the majority of family members. Although the protein encoded by this gene contains consensus nuclear localization signals, the major site for subcellular localization of expressed protein is in the cytoplasmic droplets of ejaculated spermatozoa. This protein provides a biochemical marker for studying the unique structures in spermatazoa, while attempting to further define its role in spermatogenesis. [provided by RefSeq, Jul 2008].
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Catégories SPANXB1 en vedette
SPANXB1 Anticorps
High quality antibodies with extensive validation data.
SPANXB1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB
Validations
- (4)
- (1)
N° du produit
ABIN1881824
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (2)
N° du produit
ABIN531836
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
N° du produit
ABIN531837
Quantité
200 μL
Fiche technique
Fiche technique
SPANXB1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6234137
Quantité
96 tests
Fiche technique
Fiche technique
SPANXB1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1321076
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits SPANXB1
: "SPANX gene variation in fertile and infertile males." dans: Systems biology in reproductive medicine, Vol. 55, pp. 18-26, (2010) (PubMed).: "A shared promoter region suggests a common ancestor for the human VCX/Y, SPANX, and CSAG gene families and the murine CYPT family." dans: Molecular reproduction and development, Vol. 75, Issue 2, pp. 219-29, (2007) (PubMed).
: "Dynamic structure of the SPANX gene cluster mapped to the prostate cancer susceptibility locus HPCX at Xq27." dans: Genome research, Vol. 15, Issue 11, pp. 1477-86, (2005) (PubMed).
: "The human SPANX multigene family: genomic organization, alignment and expression in male germ cells and tumor cell lines." dans: Gene, Vol. 309, Issue 2, pp. 125-33, (2003) (PubMed).
Synonymes et noms alternatifs relatifs à SPANXB1
SPANX family member B1 (SPANXB1), B1, CT11.2, SPANX-B, SPANXBProtein level used designations for SPANXB1
- SPANX family member B/F
- cancer/testis antigen 11.2
- cancer/testis antigen family 11, member 2
- nuclear-associated protein SPAN-Xb
- nuclear-associated protein SPAN-Xf
- sperm protein associated with the nucleus on the X chromosome B/F
- sperm protein associated with the nucleus, X chromosome, family member B1
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