SPANXC Produits
(SPANX Family, Member C (SPANXC))
Catégories
Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family, which is located in a gene cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a protein that localizes to the nucleus and is expressed in highly metastatic cell lines, making the protein a potential diagnostic and prognostic marker. The protein belongs to a family of cancer/testis antigens and represents a potential target for cancer immunotherapy. [provided by RefSeq, Jul 2008].
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Catégories SPANXC en vedette
SPANXC Anticorps
High quality antibodies with extensive validation data.
SPANXC recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
ELISA, WB, IHC (p), IF (p), IF (cc), IHC (fro)
Validations
- (2)
N° du produit
ABIN721675
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IHC
Validations
- (1)
N° du produit
ABIN7170464
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, WB
Validations
- (1)
N° du produit
ABIN129672
Quantité
100 μg
Fiche technique
Fiche technique
SPANXC recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6207624
Quantité
96 tests
Fiche technique
Fiche technique
Dernières publications sur nos produits SPANXC
: "Dynamic structure of the SPANX gene cluster mapped to the prostate cancer susceptibility locus HPCX at Xq27." dans: Genome research, Vol. 15, Issue 11, pp. 1477-86, (2005) (PubMed).: "Genomic organization, incidence, and localization of the SPAN-x family of cancer-testis antigens in melanoma tumors and cell lines." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 10, Issue 1 Pt 1, pp. 101-12, (2004) (PubMed).
: "The SPANX gene family of cancer/testis-specific antigens: rapid evolution and amplification in African great apes and hominids." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 9, pp. 3077-82, (2004) (PubMed).
: "The human SPANX multigene family: genomic organization, alignment and expression in male germ cells and tumor cell lines." dans: Gene, Vol. 309, Issue 2, pp. 125-33, (2003) (PubMed).
Synonymes et noms alternatifs relatifs à SPANXC
SPANX family member C (SPANXC), C, CT11.3, CTp11, SPANX-CProtein level used designations for SPANXC
- SPAN-Xc protein
- cancer-testis-associated protein CTp11
- cancer/testis antigen 11.3
- cancer/testis antigen family 11, member 3
- cancer/testis-associated protein CTp11
- cancer/testis-associated protein of 11 kD
- nuclear-associated protein SPAN-Xc
- sperm protein associated with the nucleus on the X chromosome C
- sperm protein associated with the nucleus, X chromosome, family member C
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