Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

SPEN Produits

(Spen Homolog, Transcriptional Regulator (SPEN))

Catégories

This gene encodes a hormone inducible transcriptional repressor. Repression of transcription by this gene product can occur through interactions with other repressors, by the recruitment of proteins involved in histone deacetylation, or through sequestration of transcriptional activators. The product of this gene contains a carboxy-terminal domain that permits binding to other corepressor proteins. This domain also permits interaction with members of the NuRD complex, a nucleosome remodeling protein complex that contains deacetylase activity. In addition, this repressor contains several RNA recognition motifs that confer binding to a steroid receptor RNA coactivator\; this binding can modulate the activity of both liganded and nonliganded steroid receptors. [provided by RefSeq, Jul 2008].

antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.

Catégories SPEN en vedette

SPEN Anticorps

High quality antibodies with extensive validation data.

SPEN recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Application ELISA
Validations
N° du produit ABIN7096817
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application IP
Validations
N° du produit ABIN7451040
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application ELISA
Validations
N° du produit ABIN185595
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits SPEN

Korfanty, Stokowy, Chadalski, Toma-Jonik, Vydra, Widłak, Wojtaś, Gielniewski, Widlak: "SPEN protein expression and interactions with chromatin in mouse testicular cells." dans: Reproduction (Cambridge, England), Vol. 156, Issue 3, pp. 195-206, (2018) (PubMed).

McHugh, Chen, Chow, Surka, Tran, McDonel, Pandya-Jones, Blanco, Burghard, Moradian, Sweredoski, Shishkin, Su, Lander, Hess, Plath, Guttman: "The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3." dans: Nature, Vol. 521, Issue 7551, pp. 232-6, (2015) (PubMed).

Hiriart, Gruffat, Buisson, Mikaelian, Keppler, Meresse, Mercher, Bernard, Sergeant, Manet: "Interaction of the Epstein-Barr virus mRNA export factor EB2 with human Spen proteins SHARP, OTT1, and a novel member of the family, OTT3, links Spen proteins with splicing regulation and mRNA export." dans: The Journal of biological chemistry, Vol. 280, Issue 44, pp. 36935-45, (2005) (PubMed).

Synonymes et noms alternatifs relatifs à SPEN

spen family transcriptional repressor (SPEN), SPEN homolog, transcriptional regulator (Drosophila) (Spen), HIAA0929, MINT, Mint, mKIAA0929, RBM15C, SHARP

Protein level used designations for SPEN

  • Msx2 interacting nuclear target (MINT) homolog
  • SMART/HDAC1 associated repressor protein
  • SMART/HDAC1-associated repressor protein
  • msx2-interacting protein
  • nuclear receptor transcription cofactor
  • spen homolog, transcriptional regulator (Drosophila)
  • Msx2 interacting nuclear target protein
Vous êtes ici:
Support technique