SPHK1 Produits
(Sphingosine Kinase 1 (SPHK1))
Catégories
The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].
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Catégories SPHK1 en vedette
SPHK1 Anticorps
High quality antibodies with extensive validation data.
SPHK1 Kits ELISA
Reliable ELISA kits for a wide range of species.
SPHK1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
SPHK1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (22)
- (5)
N° du produit
ABIN391346
Quantité
200 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (11)
- (5)
N° du produit
ABIN522355
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB
Validations
- (2)
- (4)
N° du produit
ABIN391345
Quantité
400 μL
Fiche technique
Fiche technique
SPHK1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6959677
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN5510666
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN4884635
Quantité
96 tests
Fiche technique
Fiche technique
SPHK1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1321162
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1321160
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Baculovirus infected Insect Cells
Validations
- (1)
N° du produit
ABIN7317043
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits SPHK1
: "Sphingosine kinase 1 expression enhances colon tumor growth." dans: Journal of translational medicine, Vol. 15, Issue 1, pp. 120, (2018) (PubMed).: "Sphingosine kinase 2 activates autophagy and protects neurons against ischemic injury through interaction with Bcl-2 via its putative BH3 domain." dans: Cell death & disease, Vol. 8, Issue 7, pp. e2912, (2018) (PubMed).
: "Disrupted epithelial/macrophage crosstalk via Spinster homologue 2-mediated S1P signaling may drive defective macrophage phagocytic function in COPD." dans: PLoS ONE, Vol. 12, Issue 11, pp. e0179577, (2017) (PubMed).
: "Overexpression of sphingosine kinase 1 is predictive of poor prognosis in human breast cancer." dans: Oncology letters, Vol. 14, Issue 1, pp. 63-72, (2017) (PubMed).
: "Predictive Value of Sphingosine Kinase 1 Expression in Papillary Thyroid Carcinoma." dans: Anticancer research, Vol. 37, Issue 10, pp. 5399-5405, (2017) (PubMed).
: "Sphingosine kinase 1 mediates AGEs-induced fibronectin upregulation in diabetic nephropathy." dans: Oncotarget, Vol. 8, Issue 45, pp. 78660-78676, (2017) (PubMed).
: "Hair Cell Loss Induced by Sphingosine and a Sphingosine Kinase Inhibitor in the Rat Cochlea." dans: Neurotoxicity research, Vol. 29, Issue 1, pp. 35-46, (2016) (PubMed).
: "Cigarette smoke inhibits efferocytosis via deregulation of sphingosine kinase signaling: reversal with exogenous S1P and the S1P analogue FTY720." dans: Journal of leukocyte biology, Vol. 100, Issue 1, pp. 195-202, (2016) (PubMed).
: "Sphingosine-1-phosphate is involved in the occlusive arteriopathy of pulmonary arterial hypertension." dans: Pulmonary circulation, Vol. 6, Issue 3, pp. 369-80, (2016) (PubMed).
: "Immunoliposome-mediated drug delivery to Plasmodium-infected and non-infected red blood cells as a dual therapeutic/prophylactic antimalarial strategy." dans: Journal of controlled release : official journal of the Controlled Release Society, Vol. 210, pp. 217-29, (2016) (PubMed).
Synonymes et noms alternatifs relatifs à SPHK1
Sphingosine kinase 1 (Sk1), sphingosine kinase 1 (SPHK1), sphingosine kinase 1 L homeolog (sphk1.L), sphingosine kinase 1 (Sphk1), 1110006G24Rik, CG1747, Dmel\\CG1747, F18E5.160, F18E5_160, SK1, Sk1, sphingosine kinase 1, SPHK, Sphk1, SPHK1, Spk1Protein level used designations for SPHK1
- CG1747-PA
- CG1747-PB
- Sk1-PA
- Sk1-PB
- sphingosine kinase 1
- sphingosine kinase I
- SK 1
- SPK 1
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