SPHK2 Produits
(Sphingosine Kinase 2 (SPHK2))
Catégories
This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011].
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Catégories SPHK2 en vedette
SPHK2 Anticorps
High quality antibodies with extensive validation data.
SPHK2 Kits ELISA
Reliable ELISA kits for a wide range of species.
SPHK2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
SPHK2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
- (4)
N° du produit
ABIN391349
Quantité
200 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC (p)
Validations
- (8)
- (2)
N° du produit
ABIN391348
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IP
Validations
- (3)
N° du produit
ABIN949506
Quantité
100 μL
Fiche technique
Fiche technique
SPHK2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1381512
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN5592624
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN456114
Quantité
96 tests
Fiche technique
Fiche technique
SPHK2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1321164
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1321166
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
N° du produit
ABIN5509153
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits SPHK2
: "Sphingosine kinase 2 activates autophagy and protects neurons against ischemic injury through interaction with Bcl-2 via its putative BH3 domain." dans: Cell death & disease, Vol. 8, Issue 7, pp. e2912, (2018) (PubMed).: "Disrupted epithelial/macrophage crosstalk via Spinster homologue 2-mediated S1P signaling may drive defective macrophage phagocytic function in COPD." dans: PLoS ONE, Vol. 12, Issue 11, pp. e0179577, (2017) (PubMed).
: "Hypoxic preconditioning protects cardiomyocytes against hypoxia/reoxygenation-induced cell apoptosis via sphingosine kinase 2 and FAK/AKT pathway." dans: Experimental and molecular pathology, Vol. 100, Issue 1, pp. 51-8, (2016) (PubMed).
: "Hair Cell Loss Induced by Sphingosine and a Sphingosine Kinase Inhibitor in the Rat Cochlea." dans: Neurotoxicity research, Vol. 29, Issue 1, pp. 35-46, (2016) (PubMed).
: "Cigarette smoke inhibits efferocytosis via deregulation of sphingosine kinase signaling: reversal with exogenous S1P and the S1P analogue FTY720." dans: Journal of leukocyte biology, Vol. 100, Issue 1, pp. 195-202, (2016) (PubMed).
: "Sphingosine-1-phosphate is involved in the occlusive arteriopathy of pulmonary arterial hypertension." dans: Pulmonary circulation, Vol. 6, Issue 3, pp. 369-80, (2016) (PubMed).
: "Down-regulation of Sphk2 suppresses bladder cancer progression." dans: Tumour biology, (2015) (PubMed).
: "Intracellular sphingosine kinase 2-derived sphingosine-1-phosphate mediates epidermal growth factor-induced ezrin-radixin-moesin phosphorylation and cancer cell invasion." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 29, Issue 11, pp. 4654-69, (2015) (PubMed).
: "Preconditioning stimuli induce autophagy via sphingosine kinase 2 in mouse cortical neurons." dans: The Journal of biological chemistry, Vol. 289, Issue 30, pp. 20845-57, (2014) (PubMed).
: "Inducible IL-33 expression by mast cells is regulated by a calcium-dependent pathway." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 189, Issue 7, pp. 3421-9, (2012) (PubMed).
Synonymes et noms alternatifs relatifs à SPHK2
Sphingosine kinase (sphK2), sphk2 (sphK2), Sphingosine kinase 2 (Sk2), sphingosine kinase 2 (SPHK2), sphingosine kinase 2 (Sphk2), C76851, CG2159, CG32484, DKFZp469F224, Dmel\\CG32484, SK-2, SK2, sk2, SK 2, Sphk2, SPK-2, SPK 2Protein level used designations for SPHK2
- Sphingosine kinase
- sphk2
- sphingosine kinase 2
- CG32484-PA
- Sk2-PA
- sphingosine kinase
- sphingosine kinase II
- sphingosine kinase 2-like
- sphingosine kinase type 2
- SK 2
- SPK 2
- Spk2, Sk2
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