SPRY2 Produits
(Sprouty Homolog 2 (SPRY2))
Catégories
This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein. [provided by RefSeq, Jul 2008].
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Catégories SPRY2 en vedette
SPRY2 Anticorps
High quality antibodies with extensive validation data.
SPRY2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
SPRY2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (3)
- (6)
N° du produit
ABIN564439
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (3)
N° du produit
ABIN7170654
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC
Validations
- (3)
N° du produit
ABIN7270554
Quantité
100 μL
Fiche technique
Fiche technique
SPRY2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6232462
Quantité
96 tests
Fiche technique
Fiche technique
SPRY2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1321263
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7405816
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7405819
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits SPRY2
: "Induction of Resistance to BRAF Inhibitor Is Associated with the Inability of Spry2 to Inhibit BRAF-V600E Activity in BRAF Mutant Cells." dans: Biomolecules & therapeutics, Vol. 23, Issue 4, pp. 320-6, (2015) (PubMed).: "Sprouty2 suppresses the inflammatory responses in rheumatoid arthritis fibroblast-like synoviocytes through regulating the Raf/ERK and PTEN/AKT signals." dans: Molecular immunology, Vol. 67, Issue 2 Pt B, pp. 532-9, (2015) (PubMed).
: "SPROUTY2 is a ?-catenin and FOXO3a target gene indicative of poor prognosis in colon cancer." dans: Oncogene, Vol. 33, Issue 15, pp. 1975-85, (2014) (PubMed).
: "Initial report on differential expression of sprouty proteins 1 and 2 in human epithelial ovarian cancer cell lines." dans: Journal of oncology, Vol. 2012, pp. 373826, (2012) (PubMed).
: "SPROUTY-2 and E-cadherin regulate reciprocally and dictate colon cancer cell tumourigenicity." dans: Oncogene, Vol. 29, Issue 34, pp. 4800-13, (2010) (PubMed).
: "Clostridium perfringens Keratitis Leading to Blinding Panophthalmitis." dans: Cornea, Vol. 27, Issue 10, pp. 1200-3, (2008) (PubMed).
: "Regulation of vascular smooth muscle cell proliferation and migration by human sprouty 2." dans: Arteriosclerosis, thrombosis, and vascular biology, Vol. 25, Issue 3, pp. 533-8, (2005) (PubMed).
: "Cerebrovascular and carotid artery disease." dans: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, Vol. 92, Issue 3, pp. 253-6, (2001) (PubMed).
Synonymes et noms alternatifs relatifs à SPRY2
sprouty RTK signaling antagonist 2 (spry2), sprouty RTK signaling antagonist 2 (SPRY2), sprouty RTK signaling antagonist 2 S homeolog (spry2.S), sprouty homolog 2 (Drosophila) (Spry2), sprouty RTK signaling antagonist 2 (Spry2), hspry2, hSPRY2, sprouty-2, sprouty2, wu:fk66h11, wu:fk93e11, Xsprouty2, xspry2, Xtsprouty2, zgc:110440Protein level used designations for SPRY2
- protein sprouty homolog 2
- sprouty 2
- spry-2
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