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SPRY2 Produits

(Sprouty Homolog 2 (SPRY2))

Catégories

This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein. [provided by RefSeq, Jul 2008].

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Catégories SPRY2 en vedette

SPRY2 Anticorps

High quality antibodies with extensive validation data.

SPRY2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SPRY2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (3)
  • (6)
N° du produit ABIN564439
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
N° du produit ABIN7170654
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC
Validations
  • (3)
N° du produit ABIN7270554
Quantité 100 μL
Fiche technique Fiche technique

SPRY2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6232462
Quantité 96 tests
Fiche technique Fiche technique

SPRY2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1321263
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7405816
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7405819
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits SPRY2

Ahn, Han, Lee: "Induction of Resistance to BRAF Inhibitor Is Associated with the Inability of Spry2 to Inhibit BRAF-V600E Activity in BRAF Mutant Cells." dans: Biomolecules & therapeutics, Vol. 23, Issue 4, pp. 320-6, (2015) (PubMed).

Zhang, Du, Zhu, Yu, Xu: "Sprouty2 suppresses the inflammatory responses in rheumatoid arthritis fibroblast-like synoviocytes through regulating the Raf/ERK and PTEN/AKT signals." dans: Molecular immunology, Vol. 67, Issue 2 Pt B, pp. 532-9, (2015) (PubMed).

Ordóñez-Morán, Irmisch, Barbáchano, Chicote, Tenbaum, Landolfi, Tabernero, Huelsken, Muñoz, Pálmer: "SPROUTY2 is a ?-catenin and FOXO3a target gene indicative of poor prognosis in colon cancer." dans: Oncogene, Vol. 33, Issue 15, pp. 1975-85, (2014) (PubMed).

Moghaddam, Amini, Wei, Pourgholami, Morris: "Initial report on differential expression of sprouty proteins 1 and 2 in human epithelial ovarian cancer cell lines." dans: Journal of oncology, Vol. 2012, pp. 373826, (2012) (PubMed).

Barbáchano, Ordóñez-Morán, García, Sánchez, Pereira, Larriba, Martínez, Hernández, Landolfi, Bonilla, Pálmer, Rojas, Muñoz: "SPROUTY-2 and E-cadherin regulate reciprocally and dictate colon cancer cell tumourigenicity." dans: Oncogene, Vol. 29, Issue 34, pp. 4800-13, (2010) (PubMed).

Hsu, Lee, Hartstein, Harocopos: "Clostridium perfringens Keratitis Leading to Blinding Panophthalmitis." dans: Cornea, Vol. 27, Issue 10, pp. 1200-3, (2008) (PubMed).

Zhang, Chaturvedi, Jaggar, Magnuson, Lee, Patel: "Regulation of vascular smooth muscle cell proliferation and migration by human sprouty 2." dans: Arteriosclerosis, thrombosis, and vascular biology, Vol. 25, Issue 3, pp. 533-8, (2005) (PubMed).

August: "Cerebrovascular and carotid artery disease." dans: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, Vol. 92, Issue 3, pp. 253-6, (2001) (PubMed).

Synonymes et noms alternatifs relatifs à SPRY2

sprouty RTK signaling antagonist 2 (spry2), sprouty RTK signaling antagonist 2 (SPRY2), sprouty RTK signaling antagonist 2 S homeolog (spry2.S), sprouty homolog 2 (Drosophila) (Spry2), sprouty RTK signaling antagonist 2 (Spry2), hspry2, hSPRY2, sprouty-2, sprouty2, wu:fk66h11, wu:fk93e11, Xsprouty2, xspry2, Xtsprouty2, zgc:110440

Protein level used designations for SPRY2

  • protein sprouty homolog 2
  • sprouty 2
  • spry-2
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