SPTLC1 Produits
(serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))
Catégories
Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. The product of this gene is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
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Catégories SPTLC1 en vedette
SPTLC1 Anticorps
High quality antibodies with extensive validation data.
SPTLC1 Kits ELISA
Reliable ELISA kits for a wide range of species.
SPTLC1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
SPTLC1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p)
Validations
- (6)
N° du produit
ABIN3187765
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (4)
N° du produit
ABIN7436414
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
N° du produit
ABIN7168895
Quantité
100 μL
Fiche technique
Fiche technique
SPTLC1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6970110
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6959376
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN5658719
Quantité
96 tests
Fiche technique
Fiche technique
SPTLC1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1321282
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7399220
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3131665
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits SPTLC1
: "Transcriptional Differences in Lipid-Metabolizing Enzymes in Murine Sebocytes Derived from Sebaceous Glands of the Skin and Preputial Glands." dans: International journal of molecular sciences, Vol. 22, Issue 21, (2021) (PubMed).: "Expression of the ORMDLS, modulators of serine palmitoyltransferase, is regulated by sphingolipids in mammalian cells." dans: The Journal of biological chemistry, Vol. 290, Issue 1, pp. 90-8, (2015) (PubMed).
: "Serine palmitoyltransferase subunit 1 is present in the endoplasmic reticulum, nucleus and focal adhesions, and functions in cell morphology." dans: Biochimica et biophysica acta, Vol. 1791, Issue 8, pp. 746-56, (2009) (PubMed).
: "Apoptotic sphingolipid signaling by ceramides in lung endothelial cells." dans: American journal of respiratory cell and molecular biology, Vol. 38, Issue 6, pp. 639-46, (2008) (PubMed).
: "Permeability barrier disruption increases the level of serine palmitoyltransferase in human epidermis." dans: The Journal of investigative dermatology, Vol. 119, Issue 5, pp. 1048-52, (2002) (PubMed).
: "Mutations in SPTLC1, encoding serine palmitoyltransferase, long chain base subunit-1, cause hereditary sensory neuropathy type I." dans: Nature genetics, Vol. 27, Issue 3, pp. 309-12, (2001) (PubMed).
: "Minocycline inhibits microglial activation and protects nigral cells after 6-hydroxydopamine injection into mouse striatum." dans: Brain research, Vol. 909, Issue 1-2, pp. 187-93, (2001) (PubMed).
: "A mammalian homolog of the yeast LCB1 encodes a component of serine palmitoyltransferase, the enzyme catalyzing the first step in sphingolipid synthesis." dans: The Journal of biological chemistry, Vol. 272, Issue 51, pp. 32108-14, (1998) (PubMed).
: "Human and murine serine-palmitoyl-CoA transferase--cloning, expression and characterization of the key enzyme in sphingolipid synthesis." dans: European journal of biochemistry / FEBS, Vol. 249, Issue 1, pp. 239-47, (1997) (PubMed).
Synonymes et noms alternatifs relatifs à SPTLC1
serine palmitoyltransferase 1 (SPT1), serine palmitoyltransferase 1 (AFUA_6G00300), Serine palmitoyltransferase 1 (PAS_FragB_0040), serine palmitoyltransferase long chain base subunit 1 (SPTLC1), serine palmitoyltransferase, long chain base subunit 1 (sptlc1), serine palmitoyltransferase, long chain base subunit 1 L homeolog (sptlc1.L), serine palmitoyltransferase, long chain base subunit 1 (Sptlc1), serine palmitoyltransferase long chain base subunit 1 (Sptlc1), Afu6g00300, ATSPT1, AW552086, C77762, E030036H05, HSAN1, HSN1, LBC1, LCB1, Lcb1, RGD1306617, SERINE PALMITOYLTRANSFERASE 1, serine palmitoyltransferase 1, SPT1, Spt1, SPTI, wu:fc75h04, wu:fp41c08, zgc:112247Protein level used designations for SPTLC1
- Serine palmitoyltransferase 1
- LCB 1
- SPT 1
- long chain base biosynthesis protein 1
- serine C-palmitoyltransferase
- serine palmitoyltransferase 1
- serine-palmitoyl-CoA transferase 1
- fc75h04
- fp41c08
- SPT1
- serine palmitoyltransferase subunit 1
- Long chain base biosynthesis protein 1
- Serine-palmitoyl-CoA transferase 1
- serine palmitoyltransferase LCB1 subunit
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