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SRF Produits

(Serum Response Factor (SRF))
This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways\; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). [provided by RefSeq, Jul 2008].

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Catégories SRF en vedette

SRF Anticorps

High quality antibodies with extensive validation data.

SRF Kits ELISA

Reliable ELISA kits for a wide range of species.

SRF Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SRF recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro)
Validations
  • (4)
N° du produit ABIN686017
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (4)
N° du produit ABIN520472
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
N° du produit ABIN6255577
Quantité 100 μL
Fiche technique Fiche technique

SRF recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6970415
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1380137
Quantité 2 x 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN5691922
Quantité 2 x 96 tests
Fiche technique Fiche technique

SRF recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1321311
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7415863
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN2731854
Quantité 20 μg
Fiche technique Fiche technique

Dernières publications sur nos produits SRF

Park, Lee, Yeom, Heo, Lim: "Neuroprotective effect of Ruminococcus albus on oxidatively stressed SH-SY5Y cells and animals." dans: Scientific reports, Vol. 7, Issue 1, pp. 14520, (2018) (PubMed).

Haikala, Marques, Turunen, Klefström: "Myc requires RhoA/SRF to reprogram glutamine metabolism." dans: Small GTPases, pp. 1-9, (2016) (PubMed).

Werfel, Jungmann, Lehmann, Ksienzyk, Bekeredjian, Kaya, Leuchs, Nordheim, Backs, Engelhardt, Katus, Müller: "Rapid and highly efficient inducible cardiac gene knockout in adult mice using AAV-mediated expression of Cre recombinase." dans: Cardiovascular research, Vol. 104, Issue 1, pp. 15-23, (2014) (PubMed).

Stern, Haverkamp, Sinske, Tedeschi, Naumann, Di Giovanni, Kochanek, Nordheim, Knöll: "The transcription factor serum response factor stimulates axon regeneration through cytoplasmic localization and cofilin interaction." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 48, pp. 18836-48, (2013) (PubMed).

Härmä, Knuuttila, Virtanen, Mirtti, Kohonen, Kovanen, Happonen, Kaewphan, Ahonen, Kallioniemi, Grafström, Lötjönen, Nees: "Lysophosphatidic acid and sphingosine-1-phosphate promote morphogenesis and block invasion of prostate cancer cells in three-dimensional organotypic models." dans: Oncogene, Vol. 31, Issue 16, pp. 2075-89, (2012) (PubMed).

Koegel, von Tobel, Schäfer, Alberti, Kremmer, Mauch, Hohl, Wang, Beer, Bloch, Nordheim, Werner: "Loss of serum response factor in keratinocytes results in hyperproliferative skin disease in mice." dans: The Journal of clinical investigation, Vol. 119, Issue 4, pp. 899-910, (2009) (PubMed).

Petit, Lindskog, Larsson, Wasteson, Athley, Breuer, Angstenberger, Hertfelder, Mattsson, Nordheim, Nelander, Lindahl: "Smooth muscle expression of lipoma preferred partner is mediated by an alternative intronic promoter that is regulated by serum response factor/myocardin." dans: Circulation research, Vol. 103, Issue 1, pp. 61-9, (2008) (PubMed).

Davis, Gupta, Pogwizd, Bacha, Jeevanandam, Gupta: "Increased expression of alternatively spliced dominant-negative isoform of SRF in human failing hearts." dans: American journal of physiology. Heart and circulatory physiology, Vol. 282, Issue 4, pp. H1521-33, (2002) (PubMed).

Synonymes et noms alternatifs relatifs à SRF

serum response factor (Srf), serum response factor (SRF), serum response factor L homeolog (srf.L), serum response factor a (srfa), AW049942, AW240594, MCM1, RGD1559787, srf, srf-A, srf1, SRFX, XSRF

Protein level used designations for SRF

  • serum response factor
  • DreSrf1
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