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SRGN Produits

(serglycin (SRGN))
This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Two transcript variants, only one of them protein-coding, have been found for this gene. [provided by RefSeq, Jul 2010].

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Catégories SRGN en vedette

SRGN Anticorps

High quality antibodies with extensive validation data.

SRGN Kits ELISA

Reliable ELISA kits for a wide range of species.

SRGN Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SRGN recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (3)
  • (2)
N° du produit ABIN519156
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (2)
N° du produit ABIN7435199
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (2)
N° du produit ABIN7436939
Quantité 100 μL
Fiche technique Fiche technique

SRGN recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6959372
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6959373
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6730770
Quantité 96 tests
Fiche technique Fiche technique

SRGN recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1321323
Quantité 2 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1321324
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7396862
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits SRGN

Ma, Gu, Li, Zhang, Cui, Qu, Wang, Humphry, Durkan, Qiu, Wang: "SRGN, a new identified shear-stress-responsive gene in endothelial cells." dans: Molecular and cellular biochemistry, Vol. 474, Issue 1-2, pp. 15-26, (2020) (PubMed).

Zhang, Deng, Zheng, Jia, Xiong, Luo, Qiu, Qiu, Yin, Lu, Liu, Gu, He: "SRGN-TGFβ2 regulatory loop confers invasion and metastasis in triple-negative breast cancer." dans: Oncogenesis, Vol. 6, Issue 7, pp. e360, (2017) (PubMed).

Reine, Vuong, Rutkovskiy, Meen, Vaage, Jenssen, Kolset: "Serglycin in Quiescent and Proliferating Primary Endothelial Cells." dans: PLoS ONE, Vol. 10, Issue 12, pp. e0145584, (2015) (PubMed).

Gasimli, Hickey, Yang, Li, dela Rosa, Nairn, Kulik, Dordick, Moremen, Dalton, Linhardt: "Changes in glycosaminoglycan structure on differentiation of human embryonic stem cells towards mesoderm and endoderm lineages." dans: Biochimica et biophysica acta, Vol. 1840, Issue 6, pp. 1993-2003, (2014) (PubMed).

Reine, Vuong, Jenssen, Kolset: "Serglycin secretion is part of the inflammatory response in activated primary human endothelial cells in vitro." dans: Biochimica et biophysica acta, Vol. 1840, Issue 8, pp. 2498-505, (2014) (PubMed).

Purushothaman, Toole: "Serglycin proteoglycan is required for multiple myeloma cell adhesion, in vivo growth, and vascularization." dans: The Journal of biological chemistry, Vol. 289, Issue 9, pp. 5499-509, (2014) (PubMed).

Chang, Chan, Braun, Green, OBrien, Chait, Day, Wight: "Monocyte-to-macrophage differentiation: synthesis and secretion of a complex extracellular matrix." dans: The Journal of biological chemistry, Vol. 287, Issue 17, pp. 14122-35, (2012) (PubMed).

Li, Ong, Cao, Xiang, Shao, Ooi, Peng, Lu, Zhang, Petillo, Qin, Bao, Zheng, Chia, Iyer, Kang, Zeng, Soo, Trent, Teh, Qian: "Serglycin is a theranostic target in nasopharyngeal carcinoma that promotes metastasis." dans: Cancer research, Vol. 71, Issue 8, pp. 3162-72, (2011) (PubMed).

Ek, Andréasson, Hober, Kampf, Pontén, Uhlén, Merz, Borrebaeck: "From gene expression analysis to tissue microarrays: a rational approach to identify therapeutic and diagnostic targets in lymphoid malignancies." dans: Molecular & cellular proteomics : MCP, Vol. 5, Issue 6, pp. 1072-81, (2006) (PubMed).

Synonymes et noms alternatifs relatifs à SRGN

serglycin (SRGN), serglycin (Srgn), Pgsg, PPG, PRG, Prg, PRG1, Prg1, Sgc

Protein level used designations for SRGN

  • hematopoetic proteoglycan core peptide
  • hematopoetic proteoglycan core protein
  • hematopoietic proteoglycan core protein
  • p.PG
  • platelet proteoglycan core protein
  • proteoglycan 1, secretory granule
  • proteoglycan protein core for mast cell secretory granule
  • secretory granule proteoglycan core peptide
  • secretory granule proteoglycan core protein
  • serglycin proteoglycan
  • gp600
  • mastocytoma proteoglycan core protein
  • proteoglycan, secretory granule
  • PG19 core protein
  • chondroitin sulfate proteoglycan core protein
  • cytolytic granule proteoglycan core protein
  • proteoglycan 10K core protein
  • proteoglycan peptide core protein
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