SRRT Produits
(Serrate RNA Effector Molecule Homolog (SRRT))
Catégories
Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA)\; however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity. Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self-renewal. Does so by directly binding SOX2 promoter and positively regulating its transcription (By similarity).
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Catégories SRRT en vedette
SRRT Anticorps
High quality antibodies with extensive validation data.
SRRT Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
SRRT recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (4)
N° du produit
ABIN526827
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (3)
N° du produit
ABIN2613482
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
N° du produit
ABIN7169355
Quantité
100 μL
Fiche technique
Fiche technique
SRRT recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1345737
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN2714949
Quantité
20 μg
Fiche technique
Fiche technique
Reactivity
Chinese Hamster
Source
Yeast
Validations
N° du produit
ABIN1635251
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits SRRT
: "Knockdown of arsenic resistance protein 2 inhibits human glioblastoma cell proliferation through the MAPK/ERK pathway." dans: Oncology reports, Vol. 40, Issue 6, pp. 3313-3322, (2019) (PubMed).: "Mutagenesis of ARS2 Domains To Assess Possible Roles in Cell Cycle Progression and MicroRNA and Replication-Dependent Histone mRNA Biogenesis." dans: Molecular and cellular biology, Vol. 35, Issue 21, pp. 3753-67, (2015) (PubMed).
: "Ars2 promotes proper replication-dependent histone mRNA 3' end formation." dans: Molecular cell, Vol. 45, Issue 1, pp. 87-98, (2012) (PubMed).
Synonymes et noms alternatifs relatifs à SRRT
Arsenic resistance protein 2 (Ars2), serrate, RNA effector molecule S homeolog (srrt.S), serrate, RNA effector molecule (SRRT), serrate RNA effector molecule homolog (Arabidopsis) (Srrt), serrate, RNA effector molecule (Srrt), serrate RNA effector molecule homolog (Arabidopsis) (srrt), 2810019G02Rik, anon-WO0118547.166, ars2, ARS2, Ars2, ars2-A, ASR2, Asr2, ASR2A, ASR2B, ASR2C, ASR2D, CG7843, CHUNP6881, Dmel\\CG7843, MGC92060, serrate, zgc:92060Protein level used designations for SRRT
- Ars2-PA
- Ars2-PC
- Ars2-PD
- Ars2-PE
- Ars2-PF
- Ars2-PG
- CG7843-PA
- CG7843-PC
- CG7843-PD
- CG7843-PE
- CG7843-PF
- CG7843-PG
- Arsenite-resistance protein 2-A
- serrate RNA effector molecule homolog A
- arsenate resistance protein 2
- arsenate resistance protein ARS2
- arsenite resistance protein
- arsenite-resistance protein 2
- serrate RNA effector molecule homolog
- Arsenite-resistance protein 2
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