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SRSF2 Produits

(serine/arginine-Rich Splicing Factor 2 (SRSF2))

Catégories

The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein and one non-coding transcript variant have been found for this gene. In addition, a pseudogene of this gene has been found on chromosome 11. [provided by RefSeq, Sep 2010].

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Catégories SRSF2 en vedette

SRSF2 Anticorps

High quality antibodies with extensive validation data.

SRSF2 Kits ELISA

Reliable ELISA kits for a wide range of species.

SRSF2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SRSF2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC
Validations
  • (4)
N° du produit ABIN1682677
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
N° du produit ABIN389301
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Chicken, Cow, Dog, Guinea Pig, Human, Monkey, Mouse, Pig, Rat, Xenopus laevis
Application WB, IHC, IHC (p)
Validations
  • (2)
N° du produit ABIN6753005
Quantité 100 μL
Fiche technique Fiche technique

SRSF2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6970115
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6959386
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Cow
Analytical Method
Validations
N° du produit ABIN1157103
Quantité 96 tests
Fiche technique Fiche technique

SRSF2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1319752
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7398260
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Rat
Source Yeast
Validations
N° du produit ABIN1675788
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits SRSF2

Wu, Nguyen, Wang, Appourchaux, Zhang, Panthu, Gruffat, Journo, Alais, Qin, Zhang, Tartour, Catez, Mahieux, Ohlmann, Liu, Du, Cimarelli: "The interferon stimulated gene 20 protein (ISG20) is an innate defense antiviral factor that discriminates self versus non-self translation." dans: PLoS pathogens, Vol. 15, Issue 10, pp. e1008093, (2019) (PubMed).

Malik, Miguez, Li, Ho, Feldman, Barmada: "Matrin 3-dependent neurotoxicity is modified by nucleic acid binding and nucleocytoplasmic localization." dans: eLife, Vol. 7, (2019) (PubMed).

Grindheim, Hollås, Raddum, Saraste, Vedeler: "Reactive oxygen species exert opposite effects on Tyr23 phosphorylation of the nuclear and cortical pools of annexin A2." dans: Journal of cell science, Vol. 129, Issue 2, pp. 314-28, (2016) (PubMed).

Guantes, Rastrojo, Neves, Lima, Aguado, Iborra: "Global variability in gene expression and alternative splicing is modulated by mitochondrial content." dans: Genome research, Vol. 25, Issue 5, pp. 633-44, (2015) (PubMed).

Zhao, Yang, Sun, Shi, Yang, Xiao, Hao, Ping, Chen, Wang, Jin, Wang, Huang, Fu, Ge, Song, Jeong, Yanagisawa, Niu, Jia, Wu, Tong, Okamoto, He, Rendtlew Danielsen, Wang, Yang: "FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis." dans: Cell research, Vol. 24, Issue 12, pp. 1403-19, (2014) (PubMed).

Sytnikova, Kubarenko, Schäfer, Weber, Niehrs: "Gadd45a is an RNA binding protein and is localized in nuclear speckles." dans: PLoS ONE, Vol. 6, Issue 1, pp. e14500, (2011) (PubMed).

Apostolatos, Apostolatos, Vickers, Watson, Song, Vale, Cooper, Sanchez-Ramos, Patel: "Vitamin A metabolite, all-trans-retinoic acid, mediates alternative splicing of protein kinase C deltaVIII (PKCdeltaVIII) isoform via splicing factor SC35." dans: The Journal of biological chemistry, Vol. 285, Issue 34, pp. 25987-95, (2010) (PubMed).

Petri, Grimmler, Over, Fischer, Gruss: "Dephosphorylation of survival motor neurons (SMN) by PPM1G/PP2Cgamma governs Cajal body localization and stability of the SMN complex." dans: The Journal of cell biology, Vol. 179, Issue 3, pp. 451-65, (2007) (PubMed).

Nie, Hampton, Fu, Liu, Findlay, Salamonsen: "A potential molecular mechanism for regulating pre-mRNA splicing of implantation-related genes through unique uterine expression of splicing factor SC35 in women and rhesus monkeys." dans: Reproduction (Cambridge, England), Vol. 124, Issue 2, pp. 209-17, (2002) (PubMed).

Sukegawa, Blobel: "A putative mammalian RNA helicase with an arginine-serine-rich domain colocalizes with a splicing factor." dans: The Journal of biological chemistry, Vol. 270, Issue 26, pp. 15702-6, (1995) (PubMed).

Synonymes et noms alternatifs relatifs à SRSF2

serine and arginine rich splicing factor 2 (SRSF2), serine/arginine-rich splicing factor 2 (Srsf2), serine and arginine rich splicing factor 2 (Srsf2), serine/arginine-rich splicing factor 2 L homeolog (srsf2.L), D11Wsu175e, MRF-1, PR264, Pr264, pr264, SC-35, sc-35, SC35, sc35, SFRS2, Sfrs2, sfrs2, SFRS2A, sfrs2a, Sfrs10, SRp30b, srp30b

Protein level used designations for SRSF2

  • SR splicing factor 2
  • splicing component, 35 kDa
  • splicing factor SC35
  • splicing factor, arginine/serine-rich 2
  • myelin regulatory factor 1
  • putative myelin regulatory factor 1
  • splicing factor Sc35
  • splicing factor, arginine/serine-rich 2 (SC-35)
  • SC-35
  • PR 264 protein
  • arginine/serine-rich2 splicing factor
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