ST14 Produits
(Suppression of Tumorigenicity 14 (Colon Carcinoma) (ST14))
Catégories
The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis. [provided by RefSeq, Jul 2008].
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Catégories ST14 en vedette
ST14 Anticorps
High quality antibodies with extensive validation data.
ST14 Kits ELISA
Reliable ELISA kits for a wide range of species.
ST14 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
ST14 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (4)
N° du produit
ABIN669726
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (3)
N° du produit
ABIN652185
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, IF, ICC
Validations
- (3)
N° du produit
ABIN6263143
Quantité
100 μL
Fiche technique
Fiche technique
ST14 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6959763
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN4883709
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6386252
Quantité
96 tests
Fiche technique
Fiche technique
ST14 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1321472
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1321474
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7505189
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits ST14
: "Developmental mechanisms driving complex tooth shape in reptiles." dans: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 249, Issue 4, pp. 441-464, (2020) (PubMed).: "Conserved function of the matriptase-prostasin proteolytic cascade during epithelial morphogenesis." dans: PLoS genetics, Vol. 15, Issue 1, pp. e1007882, (2019) (PubMed).
: "Inflammatory cytokines down-regulate the barrier-protective prostasin-matriptase proteolytic cascade early in experimental colitis." dans: The Journal of biological chemistry, Vol. 292, Issue 26, pp. 10801-10812, (2017) (PubMed).
: "Matriptase zymogen supports epithelial development, homeostasis and regeneration." dans: BMC biology, Vol. 15, Issue 1, pp. 46, (2017) (PubMed).
: "Distinct Developmental Functions of Prostasin (CAP1/PRSS8) Zymogen and Activated Prostasin." dans: The Journal of biological chemistry, Vol. 291, Issue 6, pp. 2577-82, (2016) (PubMed).
: "Targeting matriptase in breast cancer abrogates tumour progression via impairment of stromal-epithelial growth factor signalling." dans: Nature communications, Vol. 6, pp. 6776, (2015) (PubMed).
: "Matriptase promotes inflammatory cell accumulation and progression of established epidermal tumors." dans: Oncogene, Vol. 34, Issue 35, pp. 4664-72, (2015) (PubMed).
: "Epigenetic Silencing of SPINT2 Promotes Cancer Cell Motility via HGF-MET Pathway Activation in Melanoma." dans: The Journal of investigative dermatology, Vol. 135, Issue 9, pp. 2283-91, (2015) (PubMed).
: "Regulation of feto-maternal barrier by matriptase- and PAR-2-mediated signaling is required for placental morphogenesis and mouse embryonic survival." dans: PLoS genetics, Vol. 10, Issue 7, pp. e1004470, (2015) (PubMed).
: "Matriptase proteolytically activates influenza virus and promotes multicycle replication in the human airway epithelium." dans: Journal of virology, Vol. 87, Issue 8, pp. 4237-51, (2013) (PubMed).
Synonymes et noms alternatifs relatifs à ST14
suppression of tumorigenicity 14 (ST14), suppression of tumorigenicity 14 L homeolog (st14.L), suppression of tumorigenicity 14 (colon carcinoma) (St14), suppression of tumorigenicity 14 (St14), Epithin, HAI, hai, matriptase, mCAP3, MT-SP1, mt-sp1, MTSP1, mtsp1, PRSS14, prss14, Prss14, SNC19, snc19, st14, st14a, TADG15, tadg15, tmprss1, TMPRSS14, Tmprss14, XMT-SP1Protein level used designations for ST14
- membrane-type serine protease 1
- prostamin
- serine protease 14
- serine protease TADG-15
- suppression of tumorigenicity 14 (colon carcinoma, matriptase, epithin)
- suppressor of tumorigenicity 14 protein
- tumor associated differentially expressed gene 15 protein
- tumor-associated differentially-expressed gene 15 protein
- matriptase a
- suppression of tumorigenicity 14 (colon carcinoma) a
- suppressor of tumorigenicity 14 protein homolog
- suppressor of tumorigenicity protein 14
- matriptase/MT-SP1
- protease, serine, 14 (epithin)
- matriptase
- membrane-type serine protease
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