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STAT1 Produits

(Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))

Catégories

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].

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Catégories STAT1 en vedette

STAT1 Anticorps

High quality antibodies with extensive validation data.

STAT1 Kits ELISA

Reliable ELISA kits for a wide range of species.

STAT1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

STAT1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC (p), IF, FACS
Validations
  • (4)
  • (6)
N° du produit ABIN1881847
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (1)
  • (8)
N° du produit ABIN6256410
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
N° du produit ABIN7443806
Quantité 100 μL
Fiche technique Fiche technique

STAT1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Semi-Quantitative Cell ELISA
Validations
  • (2)
  • (6)
N° du produit ABIN1981837
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
  • (6)
N° du produit ABIN625230
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
  • (6)
N° du produit ABIN625231
Quantité 96 tests
Fiche technique Fiche technique

STAT1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1321588
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1321590
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN667813
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits STAT1

He, Du, Chen, Liu, Zhou, Adhikari, Rubin, Pekow, Li: "Renin-angiotensin system promotes colonic inflammation by inducing TH17 activation via JAK2/STAT pathway." dans: American journal of physiology. Gastrointestinal and liver physiology, Vol. 316, Issue 6, pp. G774-G784, (2019) (PubMed).

Liu, Wu, Zhu, Li, Liu: "IRG1 increases MHC class I level in macrophages through STAT-TAP1 axis depending on NADPH oxidase mediated reactive oxygen species." dans: International immunopharmacology, Vol. 48, pp. 76-83, (2018) (PubMed).

Chen, Zhou, Liu, Huang, Liu, Kang, Chen, Guo, Zhu, Sun: "Combination of gemcitabine and erlotinib inhibits recurrent pancreatic cancer growth in mice via the JAK-STAT pathway." dans: Oncology reports, Vol. 39, Issue 3, pp. 1081-1089, (2018) (PubMed).

Liu, Li, Liang, Li, Jiang, Chu, Yang: "Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway." dans: International journal of molecular medicine, Vol. 41, Issue 4, pp. 1867-1876, (2018) (PubMed).

Huang, Wang, Li, Wang, Yan, Zhang, Wang, Huang, Jia, Lu, Liu, Chen, Li, Cai, Jiang, Jin, Bai: "Osteoblasts secrete Cxcl9 to regulate angiogenesis in bone." dans: Nature communications, Vol. 7, pp. 13885, (2018) (PubMed).

Yang, Li, Xu, Yang, Wang, Yuan: "CT‑1042, a novel anticancer agent, exhibits effects by activating p53 and inhibiting survivin." dans: Oncology reports, Vol. 39, Issue 6, pp. 2759-2768, (2018) (PubMed).

Chen, Ding, Li, Huang, Li, Yang, Zhang, Pan, Huang, Meng, Li: "Hesperetin derivative-14 alleviates inflammation by activating PPAR-γ in mice with CCl4-induced acute liver injury and LPS-treated RAW264.7 cells." dans: Toxicology letters, Vol. 274, pp. 51-63, (2017) (PubMed).

Sharma, Bashir, Ansarullah, Faraz Khan, Ahmad, Khan et al.: "Inhibition of Src homology 2 domain containing protein tyrosine phosphatase as the possible mechanism of metformin-assisted amelioration of obesity induced insulin resistance in high fat diet fed ..." dans: Biochemical and biophysical research communications, Vol. 487, Issue 1, pp. 54-61, (2017) (PubMed).

Azad, Yin Lim, DCosta, Jones, Diana, Sansom, Kruger, Liu, McKenna, Dushek, Muschel, Fokas: "PD-L1 blockade enhances response of pancreatic ductal adenocarcinoma to radiotherapy." dans: EMBO molecular medicine, Vol. 9, Issue 2, pp. 167-180, (2017) (PubMed).

Wu, Chen, Jing, Gu, Mei, Yao, Zhou, Yang, Sun, Wang, Hu, Wüthrich, Mei: "The C-terminal tail of polycystin-1 regulates complement factor B expression by signal transducer and activator of transcription 1." dans: American journal of physiology. Renal physiology, Vol. 310, Issue 11, pp. F1284-94, (2017) (PubMed).

Synonymes et noms alternatifs relatifs à STAT1

signal transducer and activator of transcription 1 (STAT1), signal transducer and activator of transcription 1 (Stat1), signal transducer and activator of transcription 1 L homeolog (stat1.L), signal transducer and activator of transcription 1, 91kDa (STAT1), signal transducer and activator of transcription 4 (stat4), signal transducer and activator of transcription 1a (stat1a), 2010005J02Rik, AA408197, CANDF7, DD6G4-4, dZ182H3.3, ISGF-3, si:by51f19.1, si:by134g18.2, si:dz73o4.2, si:dz182h3.3, si:dz199m19.1, STAT, STAT1, stat1, STAT4, STAT91, XStat1

Protein level used designations for STAT1

  • signal transducer and activator of transcription 1-alpha/beta
  • signal transducer and activator of transcription-1
  • transcription factor ISGF-3 components p91/p84
  • signal transducer and activator of transcription 1
  • signal transducer and activator of transcription 4
  • transcription factor ISGF-3
  • activator of transcription
  • signal transduction
  • LOW QUALITY PROTEIN: signal transducer and activator of transcription 1-alpha/beta
  • signal transducer and activator of transcription 1, 91kDa
  • signal transduction and activation of transcription 1
  • signal transduction and activation of transcription 1a
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