STAT3 Produits
(Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3))
Catégories
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].
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Catégories STAT3 en vedette
STAT3 Anticorps
High quality antibodies with extensive validation data.
STAT3 Kits ELISA
Reliable ELISA kits for a wide range of species.
STAT3 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
STAT3 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (1)
- (8)
- (1)
N° du produit
ABIN2855865
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (3)
- (7)
N° du produit
ABIN6265317
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IP, IF, ICC
Validations
- (3)
- (9)
N° du produit
ABIN6256411
Quantité
100 μL
Fiche technique
Fiche technique
STAT3 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Semi-Quantitative Cell ELISA
Validations
- (3)
- (6)
N° du produit
ABIN1981839
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
- (2)
- (6)
N° du produit
ABIN625245
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
- (1)
- (3)
N° du produit
ABIN1981729
Quantité
96 tests
Fiche technique
Fiche technique
STAT3 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (2)
- (1)
N° du produit
ABIN1321594
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7125094
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1321596
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits STAT3
: "Tibetan medicine Ershiwuwei Lvxue Pill attenuates collagen-induced arthritis via inhibition of JAK2/STAT3 signaling pathway." dans: Journal of ethnopharmacology, Vol. 270, pp. 113820, (2021) (PubMed).: "Conjugation with nanodiamonds via hydrazone bond fundamentally alters intracellular distribution and activity of doxorubicin." dans: International journal of pharmaceutics, Vol. 606, pp. 120872, (2021) (PubMed).
: "Bazedoxifene Plays a Protective Role against Inflammatory Injury of Endothelial Cells by Targeting CD40." dans: Cardiovascular therapeutics, Vol. 2020, pp. 1795853, (2021) (PubMed).
: "Oleacein and Foam Cell Formation in Human Monocyte-Derived Macrophages: A Potential Strategy Against Early and Advanced Atherosclerotic Lesions." dans: Pharmaceuticals (Basel, Switzerland), Vol. 13, Issue 4, (2020) (PubMed).
: "Serum ERK1/2 proteins fluctuating with HBV infection report frequency of viral-specific CD8+ T cells and predict IFNα therapeutic effect in chronic hepatitis B patients." dans: Clinical immunology (Orlando, Fla.), Vol. 219, pp. 108570, (2020) (PubMed).
: "CCL5 derived from tumor-associated macrophages promotes prostate cancer stem cells and metastasis via activating β-catenin/STAT3 signaling." dans: Cell death & disease, Vol. 11, Issue 4, pp. 234, (2020) (PubMed).
: "Bazedoxifene inhibits PDGF-BB induced VSMC phenotypic switch via regulating the autophagy level." dans: Life sciences, Vol. 259, pp. 118397, (2020) (PubMed).
: "Extracellular vesicles secreted by hypoxia pre-challenged mesenchymal stem cells promote non-small cell lung cancer cell growth and mobility as well as macrophage M2 polarization via miR-21-5p ..." dans: Journal of experimental & clinical cancer research : CR, Vol. 38, Issue 1, pp. 62, (2019) (PubMed).
: "Opa interacting protein 5 promotes metastasis of nasopharyngeal carcinoma cells by promoting EMT via modulation of JAK2/STAT3 signal." dans: European review for medical and pharmacological sciences, Vol. 23, Issue 2, pp. 613-621, (2019) (PubMed).
: "STAT3, STAT5A, STAT5B and STAT6 proteins are overexpressed in human basal cell carcinoma." dans: Clinical and experimental dermatology, (2019) (PubMed).
Synonymes et noms alternatifs relatifs à STAT3
signal transducer and activator of transcription 3 (STAT3), signal transduction and activation of transcription 3 (stat3), signal transducer and activator of transcription 3 (stat3), signal transducer and activator of transcription 3 (Stat3), signal transducer and activator of transcription 3, gene 1 L homeolog (stat3.1.L), signal transducer and activator of transcription 3 (acute-phase response factor) (stat3), 1110034C02Rik, Aprf, APRF, aprf, AW109958, HIES, hies, stat3, wu:fc15d02, wu:fl59g06, Xstat3, z-Stat3Protein level used designations for STAT3
- signal transducer and activator of transcription 3 (acute-phase response factor)
- signal transducer and activator of transcription 3
- signal transduction and activation of transcription 3
- Signal transducer and activator of transcription 3
- signal transducer and activator of transcription 3-like
- acute phase response factor
- acute-phase response factor
- DNA-binding protein APRF
- Protein Stat3
- signal transducer and activator of transcription 3.1
- stat 3
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