STAT4 Produits
(Signal Transducer and Activator of Transcription 4 (STAT4))
Catégories
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011].
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Catégories STAT4 en vedette
STAT4 Anticorps
High quality antibodies with extensive validation data.
STAT4 Kits ELISA
Reliable ELISA kits for a wide range of species.
STAT4 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
STAT4 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (6)
N° du produit
ABIN7443809
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF
Validations
- (7)
N° du produit
ABIN7262925
Quantité
200 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IP, IF, IHC (p)
Validations
- (9)
N° du produit
ABIN563030
Quantité
100 μg
Fiche technique
Fiche technique
STAT4 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Semi-Quantitative Cell ELISA
Validations
- (3)
- (5)
N° du produit
ABIN1981841
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6970219
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6970218
Quantité
96 tests
Fiche technique
Fiche technique
STAT4 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1321598
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7417414
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3077563
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits STAT4
: "The effect of the TLR9 ligand CpG-oligodeoxynucleotide on the protective immune response to radiation-induced lung fibrosis in mice." dans: Molecular immunology, Vol. 80, pp. 33-40, (2017) (PubMed).: "Radiation-induced lung fibrosis in a tumor-bearing mouse model is associated with enhanced Type-2 immunity." dans: Journal of radiation research, Vol. 57, Issue 2, pp. 133-41, (2017) (PubMed).
: "A guanidine-rich regulatory oligodeoxynucleotide improves type-2 diabetes in obese mice by blocking T-cell differentiation." dans: EMBO molecular medicine, Vol. 4, Issue 10, pp. 1112-25, (2012) (PubMed).
: "Temporal induction pattern of STAT4 target genes defines potential for Th1 lineage-specific programming." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 6, pp. 3839-47, (2009) (PubMed).
: "High basal STAT4 balanced by STAT1 induction to control type 1 interferon effects in natural killer cells." dans: The Journal of experimental medicine, Vol. 204, Issue 10, pp. 2383-96, (2007) (PubMed).
: "Interferon alpha but not interleukin 12 activates STAT4 signaling in human vascular endothelial cells." dans: The Journal of biological chemistry, Vol. 279, Issue 25, pp. 26789-96, (2004) (PubMed).
: "PIASx is a transcriptional co-repressor of signal transducer and activator of transcription 4." dans: The Journal of biological chemistry, Vol. 278, Issue 24, pp. 21327-30, (2003) (PubMed).
: "Signaling through the JAK/STAT pathway, recent advances and future challenges." dans: Gene, Vol. 285, Issue 1-2, pp. 1-24, (2002) (PubMed).
: "Activated STAT4 and a functional role for IL-12 in human Peyer's patches." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 1, pp. 300-7, (2002) (PubMed).
: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).
Synonymes et noms alternatifs relatifs à STAT4
signal transducer and activator of transcription 4 (STAT4), signal transducer and activator of transcription 4 (stat4), signal transducer and activator of transcription 4 (Stat4), SLEB11Protein level used designations for STAT4
- signal transducer and activator of transcription 4
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