STAT5A Produits
(Signal Transducer and Activator of Transcription 5A (STAT5A))
Catégories
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. [provided by RefSeq, Jul 2008].
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Catégories STAT5A en vedette
STAT5A Anticorps
High quality antibodies with extensive validation data.
STAT5A Kits ELISA
Reliable ELISA kits for a wide range of species.
STAT5A Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
STAT5A recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p), IF (cc)
Validations
- (3)
- (1)
N° du produit
ABIN5557532
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, ELISA, FACS, ICC
Validations
- (2)
- (7)
N° du produit
ABIN1098129
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (6)
N° du produit
ABIN950127
Quantité
50 μg
Fiche technique
Fiche technique
STAT5A recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Semi-Quantitative Cell ELISA
Validations
- (1)
- (6)
N° du produit
ABIN1981843
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
- (1)
- (3)
N° du produit
ABIN1981730
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6959477
Quantité
96 tests
Fiche technique
Fiche technique
STAT5A recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1321600
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1321602
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7417432
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits STAT5A
: "Integrated Proteomic and Transcriptomic Analysis Reveals Long Noncoding RNA HOX Transcript Antisense Intergenic RNA (HOTAIR) Promotes Hepatocellular Carcinoma Cell Proliferation by Regulating Opioid ..." dans: Molecular & cellular proteomics : MCP, Vol. 17, Issue 1, pp. 146-159, (2019) (PubMed).: "STAT3, STAT5A, STAT5B and STAT6 proteins are overexpressed in human basal cell carcinoma." dans: Clinical and experimental dermatology, (2019) (PubMed).
: "Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway." dans: International journal of molecular medicine, Vol. 41, Issue 4, pp. 1867-1876, (2018) (PubMed).
: "Oral exposure to diisodecyl phthalate aggravates allergic dermatitis by oxidative stress and enhancement of thymic stromal lymphopoietin." dans: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 99, pp. 60-69, (2017) (PubMed).
: "TGF-β induces the differentiation of human CXCL13-producing CD4(+) T cells." dans: European journal of immunology, Vol. 46, Issue 2, pp. 360-71, (2016) (PubMed).
: "Expression of STAT5, COX-2 and PIAS3 in correlation with NSCLC histhopathological features." dans: PLoS ONE, Vol. 9, Issue 8, pp. e104265, (2014) (PubMed).
: "Variant G6PD levels promote tumor cell proliferation or apoptosis via the STAT3/5 pathway in the human melanoma xenograft mouse model." dans: BMC cancer, Vol. 13, Issue 1, pp. 251, (2014) (PubMed).
: "Role of prolactin in B cell regulation in multiple sclerosis." dans: Journal of neuroimmunology, Vol. 269, Issue 1-2, pp. 76-86, (2014) (PubMed).
: "Effect of suppressor of cytokine signaling 2 (SOCS2) on fat metabolism induced by growth hormone (GH) in porcine primary adipocyte." dans: Molecular biology reports, Vol. 39, Issue 9, pp. 9113-22, (2012) (PubMed).
: "Characterization of the rat oncostatin M receptor complex which resembles the human, but differs from the murine cytokine receptor." dans: PLoS ONE, Vol. 7, Issue 8, pp. e43155, (2012) (PubMed).
Synonymes et noms alternatifs relatifs à STAT5A
signal transducer and activator of transcription 5A (STAT5A), signal transducer and activator of transcription 5A (Stat5a), signal transducer and activator of transcription 5a (stat5a), signal transducer and activator of transcription 5A (LOC100348518), signal transducer and activator of transcription 5A (LOC100716811), AA959963, MGF, STAT5, Stat5, stat5, STAT5A, STAT5A/MGF, stat5b, STATA5Protein level used designations for STAT5A
- mammary gland factor STAT5A
- mammary gland factor
- signal transducer and activator of transcription 5
- STAT5A, Mammary Gland Factor
- signal transducer and activator of transcription 5A
- signal transducer and activator of transcription 5A-like
- signal transducer and activator of transcription 5B
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