STAT5B Produits
(Signal Transducer and Activator of Transcription 5B (STAT5B))
Catégories
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq, Jul 2008].
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Catégories STAT5B en vedette
STAT5B Anticorps
High quality antibodies with extensive validation data.
STAT5B Kits ELISA
Reliable ELISA kits for a wide range of species.
STAT5B Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
STAT5B recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (5)
N° du produit
ABIN563035
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IP
Validations
- (5)
N° du produit
ABIN520547
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (5)
N° du produit
ABIN520546
Quantité
100 μg
Fiche technique
Fiche technique
STAT5B recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6959478
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6970221
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN1117115
Quantité
96 tests
Fiche technique
Fiche technique
STAT5B recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7125095
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1321604
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1321606
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits STAT5B
: "Critical functions for STAT5 tetramers in the maturation and survival of natural killer cells." dans: Nature communications, Vol. 8, Issue 1, pp. 1320, (2018) (PubMed).: "TGF-β induces the differentiation of human CXCL13-producing CD4(+) T cells." dans: European journal of immunology, Vol. 46, Issue 2, pp. 360-71, (2016) (PubMed).
: "BCR-ABL affects STAT5A and STAT5B differentially." dans: PLoS ONE, Vol. 9, Issue 5, pp. e97243, (2015) (PubMed).
: "Quantitative Proteomics Analysis Reveals Novel Insights into Mechanisms of Action of Long Noncoding RNA Hox Transcript Antisense Intergenic RNA (HOTAIR) in HeLa Cells." dans: Molecular & cellular proteomics : MCP, Vol. 14, Issue 6, pp. 1447-63, (2015) (PubMed).
: "Granulocyte colony-stimulating factor potentiates all-trans retinoic acid-induced granulocytic differentiation in acute promyelocytic leukemia cell line HT93A." dans: Cancer cell international, Vol. 15, pp. 30, (2015) (PubMed).
: "Effects of Er-Zhi-Wan on microarchitecture and regulation of Wnt/?-catenin signaling pathway in alveolar bone of ovariectomized rats." dans: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, Vol. 34, Issue 1, pp. 114-9, (2014) (PubMed).
: "Expression of STAT5, COX-2 and PIAS3 in correlation with NSCLC histhopathological features." dans: PLoS ONE, Vol. 9, Issue 8, pp. e104265, (2014) (PubMed).
: "Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia." dans: Blood, Vol. 121, Issue 22, pp. 4541-50, (2013) (PubMed).
: "Signal transducer and activator of transcription 5b (Stat5b) serine 193 is a novel cytokine-induced phospho-regulatory site that is constitutively activated in primary hematopoietic malignancies." dans: The Journal of biological chemistry, Vol. 287, Issue 20, pp. 16596-608, (2012) (PubMed).
: "A novel mechanism for Fc{epsilon}RI-mediated signal transducer and activator of transcription 5 (Stat5) tyrosine phosphorylation and the selective influence of Stat5B over mast cell cytokine production." dans: The Journal of biological chemistry, (2011) (PubMed).
Synonymes et noms alternatifs relatifs à STAT5B
signal transducer and activator of transcription 5B (STAT5B), signal transducer and activator of transcription 5B (Stat5b), signal transducer and activator of transcription 5B S homeolog (stat5b.S), signal transducer and activator of transcription 5B (LOC490969), Signal transducer and activator of transcription 5B (sta5b), signal transducer and activator of transcription 5B (LOC100566752), signal transducer and activator of transcription 5B (LOC100052954), STAT5, stat5, STAT5A, STAT5BProtein level used designations for STAT5B
- transcription factor STAT5B
- Signal transducer and activator of transcription 5a
- mammary gland factor STAT5B
- signal transducer and activator of transcription 5A
- Signal transducer and activator of transcription 5B
- signal transducer and activator of transcription 5B
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