STIM1 Produits
(Stromal Interaction Molecule 1 (STIM1))
Catégories
This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6 kb from the 5' end of the RRM1 gene.[provided by RefSeq, Jan 2009].
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Catégories STIM1 en vedette
STIM1 Anticorps
High quality antibodies with extensive validation data.
STIM1 Kits ELISA
Reliable ELISA kits for a wide range of species.
STIM1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
STIM1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC (p), IF
Validations
- (20)
- (5)
N° du produit
ABIN563045
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
N° du produit
ABIN7444409
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IP, IHC (p), ICC
Validations
- (2)
- (3)
N° du produit
ABIN192394
Quantité
0.1 mg
Fiche technique
Fiche technique
STIM1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6730286
Quantité
96 tests
Fiche technique
Fiche technique
STIM1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
N° du produit
ABIN1321631
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN666653
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7418308
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits STIM1
: "Suppression of STIM1 inhibits the migration and invasion of human prostate cancer cells and is associated with PI3K/Akt signaling inactivation." dans: Oncology reports, Vol. 38, Issue 5, pp. 2629-2636, (2018) (PubMed).: "A Novel Strategy for TNF-Alpha Production by 2-APB Induced Downregulated SOCE and Upregulated HSP70 in O. tsutsugamushi-Infected Human Macrophages." dans: PLoS ONE, Vol. 11, Issue 7, pp. e0159299, (2017) (PubMed).
: "Endoplasmic Reticulum Stress and Store-Operated Calcium Entry Contribute to Usnic Acid-Induced Toxicity in Hepatic Cells." dans: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 146, Issue 1, pp. 116-26, (2015) (PubMed).
: "IL-9 induces IL-8 production via STIM1 activation and ERK phosphorylation in epidermal keratinocytes: A plausible mechanism of IL-9R in atopic dermatitis." dans: Journal of dermatological science, Vol. 78, Issue 3, pp. 206-14, (2015) (PubMed).
: "STIM1 and SLC24A4 Are Critical for Enamel Maturation." dans: Journal of dental research, Vol. 93, Issue 7 Suppl, pp. 94S-100S, (2015) (PubMed).
: "STIM1 and STIM2 proteins differently regulate endogenous store-operated channels in HEK293 cells." dans: The Journal of biological chemistry, Vol. 290, Issue 8, pp. 4717-27, (2015) (PubMed).
: "Cooperative and alternate functions for STIM1 and STIM2 in macrophage activation and in the context of inflammation." dans: Immunity, inflammation and disease, Vol. 3, Issue 3, pp. 154-70, (2015) (PubMed).
: "Conformational Changes in the Orai1 C-Terminus Evoked by STIM1 Binding." dans: PLoS ONE, Vol. 10, Issue 6, pp. e0128622, (2015) (PubMed).
: "Inside-out Ca(2+) signalling prompted by STIM1 conformational switch." dans: Nature communications, Vol. 6, pp. 7826, (2015) (PubMed).
: "Ca(2+) Channel Re-localization to Plasma-Membrane Microdomains Strengthens Activation of Ca(2+)-Dependent Nuclear Gene Expression." dans: Cell reports, Vol. 12, Issue 2, pp. 203-16, (2015) (PubMed).
Synonymes et noms alternatifs relatifs à STIM1
stromal interaction molecule 1 (STIM1), stromal interaction molecule 1 (stim1), stromal interaction molecule 1a (stim1a), stromal interaction molecule 1 L homeolog (stim1.L), stromal interaction molecule 1b (stim1b), stromal interaction molecule 1 (Stim1), D11S4896E, GOK, MGC76045, MGC154748, si:ch211-112l17.2, si:dkey-24p1.5, SIM, stim1, STIM1, Stim1, TAMProtein level used designations for STIM1
- stromal interaction molecule 1
- stromal interaction molecule 1b
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- STEAP4
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