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STK4 Produits

(serine/threonine Kinase 4 (STK4))
The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process. [provided by RefSeq, Jul 2008].

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Catégories STK4 en vedette

STK4 Anticorps

High quality antibodies with extensive validation data.

STK4 Kits ELISA

Reliable ELISA kits for a wide range of species.

STK4 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

STK4 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IF, PLA
Validations
  • (8)
N° du produit ABIN563051
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (5)
N° du produit ABIN563050
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IP, IF, IHC (p), ICC
Validations
  • (5)
N° du produit ABIN2856667
Quantité 100 μL
Fiche technique Fiche technique

STK4 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN1889361
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6231399
Quantité 96 tests
Fiche technique Fiche technique

STK4 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1321708
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1321706
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Baculovirus infected Insect Cells
Validations
  • (1)
N° du produit ABIN7317074
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits STK4

Zhang, Xu, Xu, Wei, Xu: "Protein kinase A inhibitor, H89, enhances survival and clonogenicity of dissociated human embryonic stem cells through Rho-associated coiled-coil containing protein kinase (ROCK) inhibition." dans: Human reproduction (Oxford, England), Vol. 31, Issue 4, pp. 832-43, (2016) (PubMed).

Babel, Barderas, Diaz-Uriarte, Moreno, Suarez, Fernandez-Aceñero, Salazar, Capellá, Casal: "Identification of MST1/STK4 and SULF1 proteins as autoantibody targets for the diagnosis of colorectal cancer by using phage microarrays." dans: Molecular & cellular proteomics : MCP, Vol. 10, Issue 3, pp. M110.001784, (2011) (PubMed).

Park, Kang, Lee, Zhang, Kim, Beers, Lim, Avruch, Kim, Lee: "Tumor suppressor ras association domain family 5 (RASSF5/NORE1) mediates death receptor ligand-induced apoptosis." dans: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 35029-38, (2010) (PubMed).

Ren, Yan, You, Sun: "Down-regulation of mammalian sterile 20-like kinase 1 by heat shock protein 70 mediates cisplatin resistance in prostate cancer cells." dans: Cancer research, Vol. 68, Issue 7, pp. 2266-74, (2008) (PubMed).

Lau, Murray, Houshmandi, Xu, Gutmann, Yu: "Merlin is a potent inhibitor of glioma growth." dans: Cancer research, Vol. 68, Issue 14, pp. 5733-42, (2008) (PubMed).

Seidel, Schagdarsurengin, Blümke, Würl, Pfeifer, Hauptmann, Taubert, Dammann: "Frequent hypermethylation of MST1 and MST2 in soft tissue sarcoma." dans: Molecular carcinogenesis, Vol. 46, Issue 10, pp. 865-71, (2007) (PubMed).

Jang, Yang, Srinivasan, Ye: "Akt phosphorylates MstI and prevents its proteolytic activation, blocking FOXO3 phosphorylation and nuclear translocation." dans: The Journal of biological chemistry, Vol. 282, Issue 42, pp. 30836-44, (2007) (PubMed).

Cinar, Fang, Lutchman, Di Vizio, Adam, Pavlova, Rubin, Yelick, Freeman: "The pro-apoptotic kinase Mst1 and its caspase cleavage products are direct inhibitors of Akt1." dans: The EMBO journal, Vol. 26, Issue 21, pp. 4523-34, (2007) (PubMed).

Synonymes et noms alternatifs relatifs à STK4

serine/threonine kinase 4 (STK4), serine/threonine kinase 4 (Stk4), serine/threonine kinase 4 S homeolog (stk4.S), AI447339, AU020804, Kas-2, KRS2, krs2, MST1, Mst1, mst1, TIIAC, YSK3, Ysk3, ysk3

Protein level used designations for STK4

  • MST-1
  • STE20-like kinase MST1
  • dJ211D12.2 (serine/threonine kinase 4 (MST1, KRS2))
  • kinase responsive to stress 2
  • mammalian STE20-like protein kinase 1
  • mammalian sterile 20-like 1
  • serine/threonine-protein kinase 4
  • serine/threonine-protein kinase Krs-2
  • Yeast Sps1/Ste20-related kinase 3
  • sterile 20-like kinase 1
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