STRADB Produits
(STE20-Related Kinase Adaptor beta (STRADB))
Catégories
This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011].
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Catégories STRADB en vedette
STRADB Anticorps
High quality antibodies with extensive validation data.
STRADB Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
STRADB recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (5)
N° du produit
ABIN527535
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
N° du produit
ABIN184938
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
N° du produit
ABIN7170733
Quantité
100 μg
Fiche technique
Fiche technique
STRADB recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6212609
Quantité
96 tests
Fiche technique
Fiche technique
STRADB recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (2)
N° du produit
ABIN1321745
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1321747
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1321749
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits STRADB
: "Assembly of post-receptor signaling complexes for the tumor necrosis factor receptor superfamily." dans: Advances in protein chemistry, Vol. 68, pp. 225-79, (2004) (PubMed).: "Analogies between Drosophila and mammalian TRAF pathways." dans: Progress in molecular and subcellular biology, Vol. 34, pp. 47-72, (2004) (PubMed).
: "The Toll-IL-1 receptor adaptor family grows to five members." dans: Trends in immunology, Vol. 24, Issue 6, pp. 286-90, (2003) (PubMed).
: "TRAF6 is a critical factor for dendritic cell maturation and development." dans: Immunity, Vol. 19, Issue 3, pp. 353-63, (2003) (PubMed).
: "Identification and characterization of a novel Ste20/germinal center kinase-related kinase, polyploidy-associated protein kinase." dans: The Journal of biological chemistry, Vol. 278, Issue 15, pp. 13520-30, (2003) (PubMed).
: "ILPIP, a novel anti-apoptotic protein that enhances XIAP-mediated activation of JNK1 and protection against apoptosis." dans: The Journal of biological chemistry, Vol. 277, Issue 34, pp. 30454-62, (2002) (PubMed).
: "Cloning and characterization of three novel genes, ALS2CR1, ALS2CR2, and ALS2CR3, in the juvenile amyotrophic lateral sclerosis (ALS2) critical region at chromosome 2q33-q34: candidate genes for ALS2." dans: Genomics, Vol. 71, Issue 2, pp. 200-13, (2001) (PubMed).
Synonymes et noms alternatifs relatifs à STRADB
STE20-related kinase adaptor beta (Stradb), STE20-related kinase adaptor beta (STRADB), STE20-related kinase adaptor beta L homeolog (stradb.L), AA792893, Als2cr2, als2cr2, ALS2CR2, B830008M19, CALS-21, D1Ucla2, ILPIP, ILPIPA, MGC82468, Papk, PAPK, PRO1038, RGD1559449, STRADB, SyradbProtein level used designations for STRADB
- polyploidy associated protein kinase PAPK-A
- amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 2
- STE20-related kinase adaptor beta
- STE20-related kinase adapter protein beta
- juvenile amyotrophic lateral sclerosis 2 candidate 2
- STE20-related kinase adapter protein beta-like
- ILP-interacting protein homolog
- STRAD beta
- amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein homolog
- polyploidy associated protein kinase
- polyploidy-associated protein kinase
- pseudokinase ALS2CR2
- ILP-interacting protein ILPIPA
- amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein
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