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SYK Produits

(Spleen tyrosine Kinase (SYK))

Catégories

This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010].

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Catégories SYK en vedette

SYK Anticorps

High quality antibodies with extensive validation data.

SYK Kits ELISA

Reliable ELISA kits for a wide range of species.

SYK Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SYK recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IP, IHC (p), ICC
Validations
  • (4)
  • (6)
N° du produit ABIN94475
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IF, IP, IHC (p), ICC
Validations
  • (9)
N° du produit ABIN2854855
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Monkey, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (12)
N° du produit ABIN6256708
Quantité 100 μL
Fiche technique Fiche technique

SYK recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
  • (3)
N° du produit ABIN1981728
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6970412
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6959691
Quantité 96 tests
Fiche technique Fiche technique

SYK recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1321970
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1321972
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
N° du produit ABIN5509166
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits SYK

Hasan, Rahman, Sebo, Osicka: "Distinct Spatiotemporal Distribution of Bacterial Toxin-Produced Cellular cAMP Differentially Inhibits Opsonophagocytic Signaling." dans: Toxins, Vol. 11, Issue 6, (2020) (PubMed).

Zhang, Kang, Liu, Gu, Song, Li, Wang, Yao, Li, Li, Wang, Li, Mao: "Flavanomarein inhibits high glucose-stimulated epithelial-mesenchymal transition in HK-2 cells via targeting spleen tyrosine kinase." dans: Scientific reports, Vol. 10, Issue 1, pp. 439, (2020) (PubMed).

Schweig, Yao, Beaulieu-Abdelahad, Ait-Ghezala, Mouzon, Crawford, Mullan, Paris: "Alzheimer's disease pathological lesions activate the spleen tyrosine kinase." dans: Acta neuropathologica communications, Vol. 5, Issue 1, pp. 69, (2018) (PubMed).

Köhler, Fuhr, Dinekov: "Distribution of spleen tyrosine kinase and tau phosphorylated at tyrosine 18 in a mouse model of tauopathy and in the human hippocampus." dans: Brain research, Vol. 1677, pp. 1-13, (2018) (PubMed).

Greenblatt, Park, Oh, Kim, Shin, Lee, Lee, Singh, Lee, Hu, Xiao, Charles, Penninger, Lotinun, Baron, Ghosh, Shim: "CHMP5 controls bone turnover rates by dampening NF-?B activity in osteoclasts." dans: The Journal of experimental medicine, Vol. 212, Issue 8, pp. 1283-301, (2015) (PubMed).

Nishikawa, Takahashi, Nakamori, Hosomi, Maruyama, Miyazaki, Izumi, Matsumoto: "The identification of raft-derived tau-associated vesicles that are incorporated into immature tangles and paired helical filaments." dans: Neuropathology and applied neurobiology, (2015) (PubMed).

Le Huu, Kimura, Date, Hamaguchi, Hasegawa, Hau, Fujimoto, Takehara, Matsushita: "Blockade of Syk ameliorates the development of murine sclerodermatous chronic graft-versus-host disease." dans: Journal of dermatological science, Vol. 74, Issue 3, pp. 214-21, (2014) (PubMed).

Paris, Ait-Ghezala, Bachmeier, Laco, Beaulieu-Abdelahad, Lin, Jin, Crawford, Mullan: "The spleen tyrosine kinase (Syk) regulates Alzheimer amyloid-β production and Tau hyperphosphorylation." dans: The Journal of biological chemistry, Vol. 289, Issue 49, pp. 33927-44, (2014) (PubMed).

Satoh, Tabunoki, Ishida, Yagishita, Jinnai, Futamura, Kobayashi, Toyoshima, Yoshioka, Enomoto, Arai, Saito, Arima: "Phosphorylated Syk expression is enhanced in Nasu-Hakola disease brains." dans: Neuropathology : official journal of the Japanese Society of Neuropathology, Vol. 32, Issue 2, pp. 149-57, (2012) (PubMed).

Coopman, Mueller: "The Syk tyrosine kinase: a new negative regulator in tumor growth and progression." dans: Cancer letters, Vol. 241, Issue 2, pp. 159-73, (2006) (PubMed).

Synonymes et noms alternatifs relatifs à SYK

spleen associated tyrosine kinase (syk), spleen associated tyrosine kinase (SYK), spleen tyrosine kinase (Syk), spleen associated tyrosine kinase (Syk), p72-Syk, p72syk, Sykb

Protein level used designations for SYK

  • Tyrosine-protein kinase SYK
  • tyrosine-protein kinase SYK
  • protein-tyrosine kinase
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