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SYN2 Produits

(Synapsin II (SYN2))
This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family encodes a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal. The TIMP4 gene is located within an intron of this gene and is transcribed in the opposite direction. Mutations in this gene may be associated with abnormal presynaptic function and schizophrenia. Alternative splicing of this gene results in two transcripts. [provided by RefSeq, Jul 2008].

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Catégories SYN2 en vedette

SYN2 Anticorps

High quality antibodies with extensive validation data.

SYN2 Kits ELISA

Reliable ELISA kits for a wide range of species.

SYN2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SYN2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA
Validations
  • (3)
N° du produit ABIN7239083
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Mouse
Application WB, IHC, ICC
Validations
  • (3)
N° du produit ABIN5014371
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Pig, Rat
Application WB, IHC, IP, ICC
Validations
  • (2)
  • (2)
N° du produit ABIN1742208
Quantité 50 μg
Fiche technique Fiche technique

SYN2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6959792
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6959793
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6209133
Quantité 96 tests
Fiche technique Fiche technique

SYN2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1321978
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7419376
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3073642
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits SYN2

Raphael, Webb, Gomez-Rivera, Chase Huizar, Gupta, Arulanandam, Wang, Haskins, Forsthuber: "Serum Neuroinflammatory Disease-Induced Central Nervous System Proteins Predict Clinical Onset of Experimental Autoimmune Encephalomyelitis." dans: Frontiers in immunology, Vol. 8, pp. 812, (2017) (PubMed).

Acuna, Liu, Südhof: "How to Make an Active Zone: Unexpected Universal Functional Redundancy between RIMs and RIM-BPs." dans: Neuron, Vol. 91, Issue 4, pp. 792-807, (2016) (PubMed).

Jovasevic, Corcoran, Leaderbrand, Yamawaki, Guedea, Chen, Shepherd, Radulovic: "GABAergic mechanisms regulated by miR-33 encode state-dependent fear." dans: Nature neuroscience, Vol. 18, Issue 9, pp. 1265-71, (2015) (PubMed).

Shulman, Stavsky, Fedorova, Mikulincer, Atias, Radinsky, Kahn, Slutsky, Gitler: "ATP binding to synaspsin IIa regulates usage and clustering of vesicles in terminals of hippocampal neurons." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 3, pp. 985-98, (2015) (PubMed).

Chen, Yu, Huang, Yu, Zhu, Lam, Lam, Zhou: "Prenatal transfer of polybrominated diphenyl ethers (PBDEs) results in developmental neurotoxicity in zebrafish larvae." dans: Environmental science & technology, Vol. 46, Issue 17, pp. 9727-34, (2012) (PubMed).

Petersohn, Schoch, Brinkmann, Thiel: "The human synapsin II gene promoter. Possible role for the transcription factor zif268/egr-1, polyoma enhancer activator 3, and AP2." dans: The Journal of biological chemistry, Vol. 270, Issue 41, pp. 24361-9, (1995) (PubMed).

Ferreira, Kosik, Greengard, Han: "Aberrant neurites and synaptic vesicle protein deficiency in synapsin II-depleted neurons." dans: Science (New York, N.Y.), Vol. 264, Issue 5161, pp. 977-9, (1994) (PubMed).

Thiel, Südhof, Greengard: "Synapsin II. Mapping of a domain in the NH2-terminal region which binds to small synaptic vesicles." dans: The Journal of biological chemistry, Vol. 265, Issue 27, pp. 16527-33, (1990) (PubMed).

Südhof, Czernik, Kao, Takei, Johnston, Horiuchi, Kanazir, Wagner, Perin, De Camilli: "Synapsins: mosaics of shared and individual domains in a family of synaptic vesicle phosphoproteins." dans: Science (New York, N.Y.), Vol. 245, Issue 4925, pp. 1474-80, (1989) (PubMed).

Synonymes et noms alternatifs relatifs à SYN2

synapsin II L homeolog (syn2.L), synapsin II (SYN2), synapsin IIa (syn2a), synapsin II S homeolog (syn2.S), synapsin-2 (EDI_190690), synapsin II (Syn2), 2900074L19Rik, AI836018, AI841723, MGC115109, syn1, syn2, SYN2, synII, SYNII, synIIa, SYNIIa, synIIb, SYNIIb, zgc:92311

Protein level used designations for SYN2

  • synapsin II
  • synapsin IIa
  • synapsin-2
  • synapsin2
  • synapsin-2-like
  • synapsin 2
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