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SYVN1 Produits

(Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1))

Catégories

This gene encodes a protein involved in endoplasmic reticulum (ER)-associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins. Sequence analysis identified two transcript variants that encode different isoforms. [provided by RefSeq, May 2011].

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Catégories SYVN1 en vedette

SYVN1 Anticorps

High quality antibodies with extensive validation data.

SYVN1 Kits ELISA

Reliable ELISA kits for a wide range of species.

SYVN1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SYVN1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Application WB, IHC (p), IF
Validations
  • (12)
  • (6)
N° du produit ABIN388980
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF
Validations
  • (10)
N° du produit ABIN3029082
Quantité 0.4 mL
Fiche technique Fiche technique
Reactivity Human, Rat
Application WB, ELISA, FACS, IF
Validations
  • (4)
N° du produit ABIN1590085
Quantité 100 μg
Fiche technique Fiche technique

SYVN1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1131330
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method
Validations
N° du produit ABIN1131329
Quantité 96 tests
Fiche technique Fiche technique

SYVN1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1322028
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1322026
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN2733142
Quantité 20 μg
Fiche technique Fiche technique

Dernières publications sur nos produits SYVN1

Jiang, Zhu, Zhao, Li, Liu, Pina-Crespo, Zhou, Xu, Rodriguez, Yu, Cleveland, Ravits, Da Cruz, Long, Zhang, Huang, Xu: "Membralin deficiency dysregulates astrocytic glutamate homeostasis leading to ALS-like impairment." dans: The Journal of clinical investigation, Vol. 129, Issue 8, pp. 3103-3120, (2019) (PubMed).

Xie, Tang, Song, Mancuso, Del Valle, Cao, Xiang, Dang, Lan, Sanchez, Keith, Hu, Simon: "IRE1α RNase-dependent lipid homeostasis promotes survival in Myc-transformed cancers." dans: The Journal of clinical investigation, Vol. 128, Issue 4, pp. 1300-1316, (2018) (PubMed).

Hwang, Walczak, Shaler, Olzmann, Zhang, Elias, Kopito: "Characterization of protein complexes of the endoplasmic reticulum-associated degradation E3 ubiquitin ligase Hrd1." dans: The Journal of biological chemistry, Vol. 292, Issue 22, pp. 9104-9116, (2017) (PubMed).

Peters, Déry, LeBlanc: "Familial prion protein mutants inhibit Hrd1-mediated retrotranslocation of misfolded proteins by depleting misfolded protein sensor BiP." dans: Human molecular genetics, Vol. 25, Issue 5, pp. 976-88, (2016) (PubMed).

Di, Wang, Han, Fu, Duerfeldt, Blagg, Mu: "Grp94 Protein Delivers γ-Aminobutyric Acid Type A (GABAA) Receptors to Hrd1 Protein-mediated Endoplasmic Reticulum-associated Degradation." dans: The Journal of biological chemistry, Vol. 291, Issue 18, pp. 9526-39, (2016) (PubMed).

Yang, He, Ma, Zhang, Zhu, Wan, Wang, Wang, Liu, Li: "Experimental study of the protective effects of SYVN1 against diabetic retinopathy." dans: Scientific reports, Vol. 5, pp. 14036, (2016) (PubMed).

Jung, Hong, Kim, Mook-Jung: "Acute ER stress regulates amyloid precursor protein processing through ubiquitin-dependent degradation." dans: Scientific reports, Vol. 5, pp. 8805, (2015) (PubMed).

Sun, Shi, Sha, Ji, Han, Shu, Ma, Inoue, Gao, Kim, Bu, Guber, Shen, Lee, Iwawaki, Paton, Paton, Fang, Tsai, Yates, Wu, Kersten, Long, Duhamel, Simpson, Qi: "IRE1α is an endogenous substrate of endoplasmic-reticulum-associated degradation." dans: Nature cell biology, Vol. 17, Issue 12, pp. 1546-55, (2015) (PubMed).

van den Boomen, Timms, Grice, Stagg, Skødt, Dougan, Nathan, Lehner: "TMEM129 is a Derlin-1 associated ERAD E3 ligase essential for virus-induced degradation of MHC-I." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 31, pp. 11425-30, (2014) (PubMed).

Sun, Shi, Han, Francisco, Ji, Mendonça, Liu, Locasale, Simpson, Duhamel, Kersten, Yates, Long, Qi: "Sel1L is indispensable for mammalian endoplasmic reticulum-associated degradation, endoplasmic reticulum homeostasis, and survival." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 5, pp. E582-91, (2014) (PubMed).

Synonymes et noms alternatifs relatifs à SYVN1

synoviolin 1 (SYVN1), synoviolin 1 (syvn1), synovial apoptosis inhibitor 1, synoviolin (Syvn1), synoviolin 1 (Syvn1), synoviolin 1 S homeolog (syvn1.S), synovial apoptosis inhibitor 1, synoviolin (syvn1), 1200010C09Rik, AW211966, C85322, D530017H19Rik, DER3, HRD1, hrd1, Hrd1, RGD1310488, syvn1, syvn1-a, syvn1-b, wu:fk91f10, zgc:55735, zgc:77108

Protein level used designations for SYVN1

  • E3 ubiquitin-protein ligase synoviolin
  • HMG-coA reductase degradation 1 homolog
  • synovial apoptosis inhibitor 1, synoviolin
  • synoviolin 1
  • HRD1 protein
  • LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase synoviolin
  • E3 ubiquitin-protein ligase synoviolin B
  • RING-type E3 ubiquitin transferase synoviolin B
  • Synovial apoptosis inhibitor 1-B
  • synovial apoptosis inhibitor 1-B
  • RING-type E3 ubiquitin transferase synoviolin
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