TAF4 Produits
(TAF4 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 135kDa (TAF4))
Catégories
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the larger subunits of TFIID that has been shown to potentiate transcriptional activation by retinoic acid, thyroid hormone and vitamin D3 receptors. In addition, this subunit interacts with the transcription factor CREB, which has a glutamine-rich activation domain, and binds to other proteins containing glutamine-rich regions. Aberrant binding to this subunit by proteins with expanded polyglutamine regions has been suggested as one of the pathogenetic mechanisms underlying a group of neurodegenerative disorders referred to as polyglutamine diseases. [provided by RefSeq, Jul 2008].
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Catégories TAF4 en vedette
TAF4 Anticorps
High quality antibodies with extensive validation data.
TAF4 Kits ELISA
Reliable ELISA kits for a wide range of species.
TAF4 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
TAF4 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
N° du produit
ABIN6244013
Quantité
200 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, ELISA, IF, ICC
Validations
- (3)
N° du produit
ABIN6265437
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IF
Validations
- (4)
- (3)
N° du produit
ABIN968728
Quantité
50 μg
Fiche technique
Fiche technique
TAF4 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN5648297
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN511631
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Chicken
Analytical Method
Quantitative
Validations
N° du produit
ABIN1059016
Quantité
96 tests
Fiche technique
Fiche technique
TAF4 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1322093
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3095791
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Candida albicans
Source
Yeast
Validations
N° du produit
ABIN1631845
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits TAF4
: "Redundant role of tissue-selective TAF(II)105 in B lymphocytes." dans: Molecular and cellular biology, Vol. 22, Issue 18, pp. 6564-72, (2002) (PubMed).: "Expanded polyglutamine stretches interact with TAFII130, interfering with CREB-dependent transcription. ..." dans: Nature genetics, Vol. 26, Issue 1, pp. 29-36, (2000) (PubMed).
: "Distinct subdomains of human TAFII130 are required for interactions with glutamine-rich transcriptional activators." dans: Molecular and cellular biology, Vol. 18, Issue 10, pp. 5734-43, (1998) (PubMed).
: "Human TAF(II)135 potentiates transcriptional activation by the AF-2s of the retinoic acid, vitamin D3, and thyroid hormone receptors in mammalian cells." dans: Genes & development, Vol. 11, Issue 11, pp. 1381-95, (1997) (PubMed).
Synonymes et noms alternatifs relatifs à TAF4
TBP-associated factor 4 (Taf4), Taf4p (TAF4), TATA-box binding protein associated factor 4 (TAF4), TATA-box binding protein associated factor 4 L homeolog (taf4.L), CG5444, d110, Dmel\\CG5444, dmTAF4, dTAF4, dTAFII110, dTAF[[II]]110, l(3)72Dj, p110, SR3-3, SY3-2 TAF110, TAF, TAF2C, TAF2C1, TAF4, TAF4A, TAF110, Taf110, taf110, TAFII110, TAFII130, TAFII135, TAF[II]110, TAF[[II]], TAF[[II]]110, Taf[[II]]110, TFIID, TFIID 110Protein level used designations for TAF4
- CG5444-PA
- CG5444-PB
- CG5444-PC
- CG5444-PD
- CG5444-PE
- CG5444-PF
- CG5444-PG
- CG5444-PH
- TATA-associated factor 110
- TBP associated factor 110
- TBP-associated factor
- TBP-associated factor 110
- TBP-associated factor 110kD
- Taf4-PA
- Taf4-PB
- Taf4-PC
- Taf4-PD
- Taf4-PE
- Taf4-PF
- Taf4-PG
- Taf4-PH
- lethal(3)72Dj
- hypothetical protein
- RNA polymerase II TBP-associated factor subunit C
- TAF(II)130
- TAF(II)135
- TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135 kD
- TAFII-130
- TAFII-135
- TATA box binding protein (TBP)-associated factor, RNA polymerase II, C1, 130kD
- TBP-associated factor 4
- transcription initiation factor TFIID 130 kDa subunit
- transcription initiation factor TFIID 135 kD subunit
- transcription initiation factor TFIID 135 kDa subunit
- transcription initiation factor TFIID subunit 4
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