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TARBP2 Produits

(TAR (HIV-1) RNA Binding Protein 2 (TARBP2))

Catégories

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene. [provided by RefSeq, Jul 2008].

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Catégories TARBP2 en vedette

TARBP2 Anticorps

High quality antibodies with extensive validation data.

TARBP2 Kits ELISA

Reliable ELISA kits for a wide range of species.

TARBP2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

TARBP2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (6)
N° du produit ABIN7270729
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IP
Validations
  • (4)
N° du produit ABIN520702
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IP
Validations
  • (3)
N° du produit ABIN520699
Quantité 100 μL
Fiche technique Fiche technique

TARBP2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6970562
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method
Validations
N° du produit ABIN1156063
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Cow
Analytical Method
Validations
N° du produit ABIN1156060
Quantité 96 tests
Fiche technique Fiche technique

TARBP2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1322155
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1322154
Quantité 25 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN2132068
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits TARBP2

Goodarzi, Zhang, Buss, Fish, Tavazoie, Tavazoie: "Metastasis-suppressor transcript destabilization through TARBP2 binding of mRNA hairpins." dans: Nature, Vol. 513, Issue 7517, pp. 256-60, (2014) (PubMed).

De Vito, Riggi, Cornaz, Suvà, Baumer, Provero, Stamenkovic: "A TARBP2-dependent miRNA expression profile underlies cancer stem cell properties and provides candidate therapeutic reagents in Ewing sarcoma." dans: Cancer cell, Vol. 21, Issue 6, pp. 807-21, (2012) (PubMed).

Rawlings, Krishnan, Walter: "Viral RNAi suppressor reversibly binds siRNA to outcompete Dicer and RISC via multiple turnover." dans: Journal of molecular biology, Vol. 408, Issue 2, pp. 262-76, (2011) (PubMed).

Rybak, Fuchs, Smirnova, Brandt, Pohl, Nitsch, Wulczyn: "A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment." dans: Nature cell biology, Vol. 10, Issue 8, pp. 987-93, (2008) (PubMed).

Christensen, Daher, Soye, Frankel, Alexander, Lainé, Bannwarth, Ong, Chung, Campbell, Purcell, Gatignol: "Small interfering RNAs against the TAR RNA binding protein, TRBP, a Dicer cofactor, inhibit human immunodeficiency virus type 1 long terminal repeat expression and viral production." dans: Journal of virology, Vol. 81, Issue 10, pp. 5121-31, (2007) (PubMed).

Haase, Jaskiewicz, Zhang, Lainé, Sack, Gatignol, Filipowicz: "TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing." dans: EMBO reports, Vol. 6, Issue 10, pp. 961-7, (2005) (PubMed).

Lee, Kim, Ryu, Kim, Choi, Lim, Huh, Kim, Lee, Jun, Rha, Kang, Choi: "Merlin, a tumor suppressor, interacts with transactivation-responsive RNA-binding protein and inhibits its oncogenic activity." dans: The Journal of biological chemistry, Vol. 279, Issue 29, pp. 30265-73, (2004) (PubMed).

Wu-Baer, Lane, Gaynor: "Identification of a group of cellular cofactors that stimulate the binding of RNA polymerase II and TRP-185 to human immunodeficiency virus 1 TAR RNA." dans: The Journal of biological chemistry, Vol. 271, Issue 8, pp. 4201-8, (1996) (PubMed).

Wu-Baer, Lane, Gaynor: "The cellular factor TRP-185 regulates RNA polymerase II binding to HIV-1 TAR RNA." dans: The EMBO journal, Vol. 14, Issue 23, pp. 5995-6009, (1996) (PubMed).

Gatignol, Buckler-White, Berkhout, Jeang: "Characterization of a human TAR RNA-binding protein that activates the HIV-1 LTR." dans: Science (New York, N.Y.), Vol. 251, Issue 5001, pp. 1597-600, (1991) (PubMed).

Synonymes et noms alternatifs relatifs à TARBP2

TAR (HIV-1) RNA binding protein 2 (tarbp2), TARBP2, RISC loading complex RNA binding subunit (TARBP2), TAR (HIV-1) RNA binding protein 2 L homeolog (tarbp2.L), TARBP2, RISC loading complex RNA binding subunit (Tarbp2), TAR (HIV) RNA binding protein 2 (tarbp2), fj51e12, LOQS, MGC97783, Prbp, TARBP2, trbp, TRBP, trbp1, TRBP1, trbp2, TRBP2, wu:fj51e12, zgc:63778

Protein level used designations for TARBP2

  • TAR (HIV-1) RNA binding protein 2
  • RISC-loading complex subunit tarbp2
  • RISC-loading complex subunit TARBP2
  • TAR (HIV) RNA binding protein 2
  • TAR (HIV) RNA-binding protein 2
  • TAR (HIV) RNA-binding protein TRBP1
  • TAR RNA binding protein 2
  • TAR RNA-binding protein 2
  • trans-activation responsive RNA-binding protein
  • trans-activation-responsive RNA-binding protein
  • PRM-1 RNA-binding protein
  • protamine-1 RNA-binding protein
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